• ENSG00000091140
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000091140

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000205402 ENSG00000091140 HEK293_OSMI2_2hA HEK293_TMG_2hB DLD protein_coding protein_coding 51.37081 20.43653 78.26503 0.5571485 3.24542 1.936696 16.79264 12.15643 21.82070 1.820553 1.326547 0.8434528 0.4007833 0.5988000 0.2788333 -0.3199667 0.03986746 0.03365746 FALSE TRUE
ENST00000417551 ENSG00000091140 HEK293_OSMI2_2hA HEK293_TMG_2hB DLD protein_coding nonsense_mediated_decay 51.37081 20.43653 78.26503 0.5571485 3.24542 1.936696 29.57844 6.74685 49.45211 1.803034 1.167611 2.8719010 0.5061500 0.3272333 0.6330667 0.3058333 0.03365746 0.03365746 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000091140 E001 3.1776035 0.0051403809 1.140124e-02 3.212016e-02 7 107891143 107891161 19 + 0.673 0.196 -2.696
ENSG00000091140 E002 3.5442214 0.0102014074 4.343171e-02 9.735200e-02 7 107891162 107891163 2 + 0.689 0.331 -1.765
ENSG00000091140 E003 6.7572238 0.0031604642 2.009716e-02 5.169374e-02 7 107891164 107891172 9 + 0.915 0.587 -1.337
ENSG00000091140 E004 6.9087392 0.0036416382 1.682738e-02 4.454796e-02 7 107891173 107891173 1 + 0.925 0.587 -1.374
ENSG00000091140 E005 36.7627200 0.0005885941 2.672152e-06 2.022740e-05 7 107891174 107891182 9 + 1.601 1.285 -1.089
ENSG00000091140 E006 52.2868753 0.0006947073 1.428689e-05 9.155704e-05 7 107891183 107891185 3 + 1.737 1.503 -0.795
ENSG00000091140 E007 116.1195368 0.0083624647 7.263565e-03 2.191040e-02 7 107891186 107891216 31 + 2.057 1.924 -0.448
ENSG00000091140 E008 199.3442359 0.0054743599 1.682561e-02 4.454459e-02 7 107891217 107891289 73 + 2.278 2.194 -0.283
ENSG00000091140 E009 0.1515154 0.0434115047 1.000000e+00   7 107891430 107891613 184 + 0.074 0.000 -7.906
ENSG00000091140 E010 268.2922695 0.0023647667 1.250087e-05 8.123248e-05 7 107893200 107893278 79 + 2.416 2.294 -0.409
ENSG00000091140 E011 0.0000000       7 107893279 107893554 276 +      
ENSG00000091140 E012 296.6832383 0.0001935738 4.647359e-09 6.097994e-08 7 107901738 107901817 80 + 2.457 2.342 -0.384
ENSG00000091140 E013 321.6883280 0.0001543931 1.046374e-10 1.840769e-09 7 107902325 107902393 69 + 2.495 2.373 -0.409
ENSG00000091140 E014 221.3821317 0.0001866237 1.857929e-06 1.455963e-05 7 107903478 107903502 25 + 2.328 2.222 -0.353
ENSG00000091140 E015 295.4971952 0.0001635516 8.934616e-09 1.111456e-07 7 107903503 107903547 45 + 2.454 2.342 -0.374
ENSG00000091140 E016 7.7581021 0.1929680746 3.830082e-01 5.271629e-01 7 107903548 107903776 229 + 0.934 0.768 -0.645
ENSG00000091140 E017 2.7764390 0.0056203489 7.353115e-01 8.260988e-01 7 107904663 107904667 5 + 0.556 0.517 -0.183
ENSG00000091140 E018 4.0028437 0.0167034808 7.726686e-01 8.532724e-01 7 107904668 107904746 79 + 0.673 0.646 -0.114
ENSG00000091140 E019 3.1860477 0.0568882408 2.743325e-01 4.134663e-01 7 107904747 107904862 116 + 0.637 0.433 -0.964
ENSG00000091140 E020 4.4102622 0.0408190392 3.468346e-01 4.909792e-01 7 107904863 107904957 95 + 0.737 0.585 -0.644
ENSG00000091140 E021 362.1741657 0.0032814724 9.011667e-03 2.630803e-02 7 107904958 107905058 101 + 2.530 2.466 -0.213
ENSG00000091140 E022 426.6671006 0.0033339966 4.923329e-02 1.077978e-01 7 107905361 107905504 144 + 2.595 2.555 -0.131
ENSG00000091140 E023 0.4449813 0.0213115652 7.589449e-01 8.434170e-01 7 107905505 107905763 259 + 0.137 0.196 0.623
ENSG00000091140 E024 139.1248992 0.0004753339 7.910409e-01 8.663548e-01 7 107906267 107906270 4 + 2.095 2.113 0.060
ENSG00000091140 E025 350.7018070 0.0002367159 3.437571e-02 8.047663e-02 7 107906271 107906368 98 + 2.504 2.485 -0.064
ENSG00000091140 E026 0.4804688 0.0217307735 7.569575e-01 8.419197e-01 7 107906369 107906369 1 + 0.137 0.196 0.625
ENSG00000091140 E027 532.1718979 0.0002320535 2.653499e-03 9.233633e-03 7 107915506 107915696 191 + 2.687 2.660 -0.090
ENSG00000091140 E028 459.5552435 0.0002653334 3.884104e-01 5.324846e-01 7 107916794 107916964 171 + 2.613 2.624 0.036
ENSG00000091140 E029 581.7642642 0.0001346847 2.082397e-01 3.363749e-01 7 107917273 107917462 190 + 2.718 2.725 0.024
ENSG00000091140 E030 491.4363697 0.0001817409 3.244962e-03 1.098707e-02 7 107917924 107918061 138 + 2.623 2.704 0.268
ENSG00000091140 E031 326.7264345 0.0001620103 8.921986e-09 1.109958e-07 7 107919010 107919099 90 + 2.423 2.572 0.499
ENSG00000091140 E032 360.6992272 0.0001571518 3.706669e-33 7.881227e-31 7 107919194 107919383 190 + 2.423 2.686 0.878
ENSG00000091140 E033 782.0755007 0.0126131622 1.933365e-06 1.508713e-05 7 107919384 107921198 1815 + 2.751 3.028 0.919
ENSG00000091140 E034 0.3030308 0.3849895869 8.311057e-01   7 107931431 107931730 300 + 0.137 0.000 -8.913