ENSG00000089159

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000228307	ENSG00000089159	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PXN	protein_coding	protein_coding	19.73113	29.47952	14.13978	2.570665	0.2725253	-1.059423	1.501528	3.046028	1.8017682	0.3820917	0.3271256	-0.7542596	0.07250000	0.10276667	0.12666667	0.023900000	0.7023443953	0.0001167848	FALSE	TRUE
ENST00000267257	ENSG00000089159	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PXN	protein_coding	protein_coding	19.73113	29.47952	14.13978	2.570665	0.2725253	-1.059423	1.322558	1.431313	1.0142707	0.4684444	0.2288965	-0.4927868	0.07190000	0.04883333	0.07216667	0.023333333	0.6464228576	0.0001167848	FALSE	TRUE
ENST00000424649	ENSG00000089159	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PXN	protein_coding	protein_coding	19.73113	29.47952	14.13978	2.570665	0.2725253	-1.059423	10.774999	18.120864	6.5282898	1.4940407	0.0627506	-1.4714624	0.52600417	0.61566667	0.46206667	-0.153600000	0.0001167848	0.0001167848	FALSE	TRUE
ENST00000536957	ENSG00000089159	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PXN	protein_coding	protein_coding	19.73113	29.47952	14.13978	2.570665	0.2725253	-1.059423	1.459182	2.070928	0.8686035	0.1439918	0.1384718	-1.2439432	0.07662917	0.07046667	0.06170000	-0.008766667	0.7849902427	0.0001167848	FALSE	TRUE
ENST00000637386	ENSG00000089159	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PXN	protein_coding	protein_coding	19.73113	29.47952	14.13978	2.570665	0.2725253	-1.059423	1.861649	2.095198	1.1264799	0.1032825	0.6062516	-0.8893839	0.09595417	0.07160000	0.07813333	0.006533333	0.8972105389	0.0001167848	FALSE	FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
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width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000089159	E001	0.4751703	0.0207404962	9.182440e-01	9.523419e-01	12	120210439	120210446	8	-	0.166	0.163	-0.031
ENSG00000089159	E002	2.6142338	0.0057803867	3.598194e-01	5.041304e-01	12	120210447	120210447	1	-	0.379	0.572	0.971
ENSG00000089159	E003	2.8356790	0.0053155092	2.869324e-01	4.273802e-01	12	120210448	120210450	3	-	0.379	0.598	1.087
ENSG00000089159	E004	1225.3648224	0.0039552437	4.123477e-10	6.561187e-09	12	120210451	120212313	1863	-	2.894	3.094	0.664
ENSG00000089159	E005	72.5282441	0.0003931815	7.523947e-01	8.385966e-01	12	120212314	120212350	37	-	1.779	1.838	0.201
ENSG00000089159	E006	173.7743265	0.0002461839	6.755227e-01	7.807780e-01	12	120212351	120212580	230	-	2.169	2.202	0.112
ENSG00000089159	E007	162.2169357	0.0017369105	1.873840e-02	4.876014e-02	12	120213842	120213990	149	-	2.187	2.153	-0.115
ENSG00000089159	E008	128.9287157	0.0023788025	9.578399e-02	1.840648e-01	12	120214136	120214217	82	-	2.078	2.059	-0.063
ENSG00000089159	E009	81.9007277	0.0003652797	1.039866e-01	1.965701e-01	12	120214825	120214835	11	-	1.888	1.865	-0.078
ENSG00000089159	E010	162.3528905	0.0018962420	4.202087e-01	5.634332e-01	12	120214836	120214998	163	-	2.152	2.171	0.063
ENSG00000089159	E011	125.5019195	0.0007744176	4.713753e-01	6.104941e-01	12	120215103	120215240	138	-	2.037	2.057	0.068
ENSG00000089159	E012	69.6102593	0.0003994830	9.715097e-01	9.861874e-01	12	120215241	120215273	33	-	1.765	1.812	0.159
ENSG00000089159	E013	18.3496576	0.0013445356	1.051313e-02	3.000921e-02	12	120215274	120215417	144	-	1.359	1.192	-0.584
ENSG00000089159	E014	41.8233027	0.0005392515	1.035275e-01	1.958730e-01	12	120215560	120215661	102	-	1.622	1.573	-0.167
ENSG00000089159	E015	15.0132198	0.0012132067	7.181895e-08	7.497181e-07	12	120215930	120216090	161	-	1.417	0.995	-1.499
ENSG00000089159	E016	35.6490136	0.0028796483	1.874094e-02	4.876610e-02	12	120216273	120216581	309	-	1.598	1.489	-0.371
ENSG00000089159	E017	3.1826074	0.0053811519	2.607062e-02	6.408711e-02	12	120216582	120216840	259	-	0.786	0.484	-1.320
ENSG00000089159	E018	4.2447184	0.0051937783	8.796942e-01	9.267839e-01	12	120216841	120217116	276	-	0.674	0.688	0.058
ENSG00000089159	E019	11.1993377	0.0052430940	1.334394e-07	1.323406e-06	12	120219207	120220091	885	-	1.332	0.840	-1.789
ENSG00000089159	E020	63.5990525	0.0003862809	6.745844e-01	7.800647e-01	12	120221623	120221642	20	-	1.744	1.768	0.084
ENSG00000089159	E021	118.9054490	0.0003341140	4.269141e-01	5.697491e-01	12	120221643	120221758	116	-	2.016	2.033	0.058
ENSG00000089159	E022	128.4146237	0.0012492311	1.768315e-02	4.645256e-02	12	120222549	120222675	127	-	2.091	2.050	-0.136
ENSG00000089159	E023	76.6425955	0.0003320716	9.597155e-02	1.843388e-01	12	120222676	120222716	41	-	1.861	1.834	-0.091
ENSG00000089159	E024	62.1036138	0.0004160051	3.199232e-01	4.630061e-01	12	120222717	120222733	17	-	1.754	1.751	-0.011
ENSG00000089159	E025	54.1090929	0.0004783821	9.330792e-01	9.618254e-01	12	120222734	120222736	3	-	1.668	1.709	0.137
ENSG00000089159	E026	63.6530259	0.0005429520	8.119324e-01	8.806921e-01	12	120222737	120222750	14	-	1.740	1.773	0.114
ENSG00000089159	E027	140.2053102	0.0007572916	1.943188e-03	7.050564e-03	12	120222863	120222999	137	-	2.143	2.085	-0.194
ENSG00000089159	E028	59.5293368	0.0034336243	1.330912e-02	3.663987e-02	12	120223718	120223719	2	-	1.798	1.710	-0.299
ENSG00000089159	E029	111.6571947	0.0003335029	9.286887e-04	3.714892e-03	12	120223720	120223833	114	-	2.057	1.984	-0.243
ENSG00000089159	E030	48.9255238	0.0005534142	1.008157e-02	2.896147e-02	12	120224151	120224153	3	-	1.717	1.626	-0.311
ENSG00000089159	E031	55.5458399	0.0034209112	2.690749e-02	6.579683e-02	12	120224154	120224174	21	-	1.765	1.685	-0.271
ENSG00000089159	E032	104.7626158	0.0012486939	4.747232e-03	1.522523e-02	12	120224175	120224377	203	-	2.026	1.960	-0.219
ENSG00000089159	E033	1.1802048	0.0111861284	9.081176e-01	9.456601e-01	12	120224643	120224727	85	-	0.286	0.330	0.292
ENSG00000089159	E034	0.3634088	0.3368355795	6.317012e-01		12	120224728	120224750	23	-	0.000	0.164	11.031
ENSG00000089159	E035	0.1472490	0.0424190549	2.150246e-01		12	120225909	120226069	161	-	0.166	0.000	-12.799
ENSG00000089159	E036	1.5029146	0.0101542558	2.329140e-01	3.658839e-01	12	120226153	120226352	200	-	0.166	0.415	1.781
ENSG00000089159	E037	2.5474114	0.0068765141	3.612570e-01	5.056562e-01	12	120226353	120226361	9	-	0.379	0.572	0.969
ENSG00000089159	E038	22.7532666	0.0014578172	5.279819e-01	6.609001e-01	12	120226362	120226605	244	-	1.260	1.355	0.332
ENSG00000089159	E039	13.6458350	0.0013126706	5.490798e-01	6.788499e-01	12	120226606	120226654	49	-	1.132	1.116	-0.056
ENSG00000089159	E040	25.0533753	0.0043228477	5.989987e-01	7.204984e-01	12	120226655	120226838	184	-	1.312	1.400	0.305
ENSG00000089159	E041	22.3733279	0.0386133511	8.435730e-01	9.025939e-01	12	120226839	120227117	279	-	1.312	1.336	0.084
ENSG00000089159	E042	0.0000000				12	120248716	120248750	35	-
ENSG00000089159	E043	0.0000000				12	120249883	120250161	279	-
ENSG00000089159	E044	0.1472490	0.0424190549	2.150246e-01		12	120264232	120264316	85	-	0.166	0.000	-12.799
ENSG00000089159	E045	46.9583746	0.0231315040	1.491320e-01	2.604935e-01	12	120265617	120265771	155	-	1.685	1.614	-0.244

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000089159

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3