ENSG00000083807

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000594786 ENSG00000083807 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC27A5 protein_coding protein_coding 35.30525 72.25949 14.8305 2.164163 0.1763824 -2.283847 23.917761 51.179030 8.9402767 1.2521442 0.47080365 -2.515830 0.65919167 0.70853333 0.60273333 -0.105800000 0.03200623 0.0009090817 FALSE FALSE
ENST00000599700 ENSG00000083807 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC27A5 protein_coding processed_transcript 35.30525 72.25949 14.8305 2.164163 0.1763824 -2.283847 6.876127 14.191392 3.0914608 0.3721177 0.41529995 -2.195013 0.19571667 0.19653333 0.20826667 0.011733333 0.92826662 0.0009090817 FALSE FALSE
ENST00000601997 ENSG00000083807 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC27A5 protein_coding retained_intron 35.30525 72.25949 14.8305 2.164163 0.1763824 -2.283847 1.665118 2.952252 0.6224094 0.3847989 0.03156499 -2.227764 0.05276250 0.04096667 0.04200000 0.001033333 0.95707481 0.0009090817   FALSE
MSTRG.17861.6 ENSG00000083807 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC27A5 protein_coding   35.30525 72.25949 14.8305 2.164163 0.1763824 -2.283847 1.759947 2.830413 1.3350221 0.8965331 0.37820144 -1.078471 0.05227083 0.03850000 0.09046667 0.051966667 0.26297786 0.0009090817   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000083807 E001 16.3494011 0.0136323584 1.848253e-02 0.0481916277 19 58479512 58480720 1209 - 1.299 1.024 -0.985
ENSG00000083807 E002 4.3528931 0.1727641171 3.991281e-02 0.0908730153 19 58480721 58480780 60 - 0.947 0.501 -1.858
ENSG00000083807 E003 3.1498732 0.0591589131 1.200223e-02 0.0335361916 19 58480781 58480805 25 - 0.863 0.395 -2.087
ENSG00000083807 E004 0.1451727 0.0433756421 6.587587e-02   19 58481064 58481187 124 - 0.252 0.000 -12.668
ENSG00000083807 E005 1.6188288 0.0100676504 5.610862e-01 0.6889769087 19 58481545 58481581 37 - 0.411 0.288 -0.742
ENSG00000083807 E006 3.5508447 0.1188352206 2.343486e-01 0.3675827472 19 58483532 58483646 115 - 0.757 0.480 -1.225
ENSG00000083807 E007 11.7227731 0.0066839696 6.073277e-02 0.1278666366 19 58492454 58492576 123 - 1.134 0.896 -0.876
ENSG00000083807 E008 10.4959226 0.0315570730 6.012037e-03 0.0186424824 19 58492577 58492640 64 - 1.204 0.824 -1.402
ENSG00000083807 E009 4.6339323 0.0035923587 6.813001e-02 0.1402647976 19 58498333 58498336 4 - 0.252 0.639 2.092
ENSG00000083807 E010 65.5226125 0.0010110475 3.109115e-01 0.4533515694 19 58498337 58498385 49 - 1.598 1.655 0.194
ENSG00000083807 E011 149.5414333 0.0003683015 2.533882e-01 0.3898994545 19 58498386 58498474 89 - 1.966 2.004 0.129
ENSG00000083807 E012 127.5119850 0.0002849910 1.420653e-01 0.2508537979 19 58498475 58498493 19 - 1.880 1.937 0.193
ENSG00000083807 E013 392.4206058 0.0004557096 6.804571e-03 0.0207151788 19 58498494 58498691 198 - 2.365 2.422 0.188
ENSG00000083807 E014 272.9364657 0.0001871821 8.761746e-02 0.1715184089 19 58498785 58498915 131 - 2.219 2.260 0.137
ENSG00000083807 E015 20.0915685 0.0039050619 5.826751e-01 0.7069792548 19 58498916 58499122 207 - 1.203 1.136 -0.241
ENSG00000083807 E016 229.9517103 0.0055604265 9.099014e-01 0.9467240991 19 58499123 58499220 98 - 2.192 2.180 -0.040
ENSG00000083807 E017 39.0792361 0.0010950355 4.833871e-01 0.6213909005 19 58499221 58499275 55 - 1.479 1.417 -0.214
ENSG00000083807 E018 2.3478258 0.0070286591 1.271242e-02 0.0352361920 19 58499395 58499491 97 - 0.758 0.317 -2.136
ENSG00000083807 E019 3.7859072 0.0044745629 5.989839e-02 0.1264352219 19 58499492 58499690 199 - 0.814 0.498 -1.360
ENSG00000083807 E020 2.2800610 0.0063545778 3.129728e-05 0.0001853968 19 58499691 58500123 433 - 0.908 0.223 -3.399
ENSG00000083807 E021 0.8470867 0.0145379643 2.166789e-02 0.0549873534 19 58500339 58500429 91 - 0.527 0.104 -3.135
ENSG00000083807 E022 0.4783925 0.0223806938 4.156385e-02 0.0939321874 19 58500512 58500593 82 - 0.411 0.055 -3.551
ENSG00000083807 E023 0.4460135 0.0253681140 1.404527e-03 0.0053211357 19 58500594 58500706 113 - 0.527 0.000 -14.385
ENSG00000083807 E024 0.8126314 0.0153787590 1.280017e-03 0.0049102063 19 58501286 58501410 125 - 0.618 0.055 -4.550
ENSG00000083807 E025 1.8445430 0.0077881889 2.477637e-03 0.0086970702 19 58507382 58509846 2465 - 0.758 0.223 -2.814
ENSG00000083807 E026 1.0382438 0.0116796502 3.484288e-05 0.0002037874 19 58509847 58510005 159 - 0.758 0.055 -5.138
ENSG00000083807 E027 2.1390530 0.0067371140 7.790584e-03 0.0232520852 19 58510006 58510720 715 - 0.758 0.288 -2.329
ENSG00000083807 E028 0.9631001 0.3319430931 2.209203e-01 0.3515378356 19 58510721 58510930 210 - 0.411 0.154 -1.888
ENSG00000083807 E029 0.7761102 0.0583918253 5.882383e-01 0.7114537115 19 58510931 58511267 337 - 0.252 0.148 -0.955
ENSG00000083807 E030 0.9180607 0.0135808317 7.479985e-01 0.8353777359 19 58511268 58511519 252 - 0.252 0.187 -0.550
ENSG00000083807 E031 2.7720563 0.0056591622 3.693183e-05 0.0002146336 19 58511520 58512413 894 - 0.948 0.288 -3.066