ENSG00000082805

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360905 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding protein_coding 8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 0.5685801 0.7013559 0.000000 0.3816576 0.0000000 -6.1524996 0.07398333 0.07593333 0.00000000 -0.07593333 1.205399e-01 2.271283e-10 FALSE TRUE
ENST00000397203 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding protein_coding 8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 1.3098546 0.5148590 2.129051 0.5148590 0.5135134 2.0269691 0.14779583 0.04936667 0.21986667 0.17050000 1.393059e-01 2.271283e-10 FALSE TRUE
ENST00000543086 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding protein_coding 8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 0.9008876 0.1645470 2.521943 0.1645470 0.4919384 3.8585573 0.09890833 0.01913333 0.25370000 0.23456667 2.368032e-02 2.271283e-10 FALSE TRUE
ENST00000611180 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding protein_coding 8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 0.4661154 0.0000000 1.905832 0.0000000 0.5950600 7.5818275 0.04889583 0.00000000 0.18316667 0.18316667 2.271283e-10 2.271283e-10 FALSE TRUE
ENST00000691140 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding processed_transcript 8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 0.5708725 1.8871704 0.000000 0.9546702 0.0000000 -7.5677054 0.06525833 0.23236667 0.00000000 -0.23236667 1.584090e-01 2.271283e-10   FALSE
MSTRG.6623.22 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding   8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 1.2371749 0.7306673 0.406089 0.3712393 0.2690846 -0.8319335 0.15383750 0.08083333 0.04203333 -0.03880000 8.827764e-01 2.271283e-10 FALSE TRUE
MSTRG.6623.32 ENSG00000082805 HEK293_OSMI2_2hA HEK293_TMG_2hB ERC1 protein_coding   8.606 8.929851 10.05512 0.7873935 0.6992865 0.1710416 2.0995841 2.8424680 1.933897 0.3690913 0.7756869 -0.5532587 0.23891667 0.31613333 0.18383333 -0.13230000 4.120058e-01 2.271283e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000082805 E001 0.0000000       12 990282 990340 59 +      
ENSG00000082805 E002 0.1515154 0.0424082633 5.494566e-01   12 990341 990508 168 +      
ENSG00000082805 E003 2.1047140 0.0071381202 5.089816e-02 1.107671e-01 12 990509 990629 121 +      
ENSG00000082805 E004 0.2924217 0.0290785164 2.378579e-01   12 991208 991222 15 +      
ENSG00000082805 E005 0.2924217 0.0290785164 2.378579e-01   12 991223 991224 2 +      
ENSG00000082805 E006 0.2924217 0.0290785164 2.378579e-01   12 991225 991228 4 +      
ENSG00000082805 E007 0.5954526 0.0184419406 4.937136e-02 1.080390e-01 12 991229 991232 4 +      
ENSG00000082805 E008 0.7406253 0.0154685896 2.391672e-02 5.963424e-02 12 991233 991237 5 +      
ENSG00000082805 E009 0.8878743 0.0131261190 1.177546e-02 3.299523e-02 12 991238 991247 10 +      
ENSG00000082805 E010 1.3318114 0.0096139712 1.516594e-03 5.689728e-03 12 991248 991252 5 +      
ENSG00000082805 E011 1.6305759 0.0084153883 4.009416e-04 1.778065e-03 12 991253 991262 10 +      
ENSG00000082805 E012 1.6305759 0.0084153883 4.009416e-04 1.778065e-03 12 991263 991266 4 +      
ENSG00000082805 E013 1.8122802 0.0077989064 3.853991e-03 1.273218e-02 12 991267 991269 3 +      
ENSG00000082805 E014 2.5099279 0.0065954013 2.011971e-02 5.173835e-02 12 991270 991272 3 +      
ENSG00000082805 E015 8.5637308 0.1111975849 8.449721e-02 1.665929e-01 12 991273 991322 50 +      
ENSG00000082805 E016 10.1494046 0.0274529567 1.661106e-02 4.408247e-02 12 991323 991487 165 +      
ENSG00000082805 E017 0.3268771 0.0280056042 9.299903e-01   12 991560 991567 8 +      
ENSG00000082805 E018 0.3268771 0.0280056042 9.299903e-01   12 991568 991596 29 +      
ENSG00000082805 E019 0.4783925 0.0207021016 6.416615e-01 7.546426e-01 12 991597 991619 23 +      
ENSG00000082805 E020 0.1472490 0.0427770688 5.495824e-01   12 991622 991795 174 +      
ENSG00000082805 E021 1.6230978 0.0082900123 6.629720e-01 7.711411e-01 12 998324 998482 159 +      
ENSG00000082805 E022 0.1817044 0.0382619011 4.337212e-01   12 1020675 1020776 102 +      
ENSG00000082805 E023 0.1472490 0.0427770688 5.495824e-01   12 1027423 1027539 117 +      
ENSG00000082805 E024 15.0278140 0.0077703965 2.848481e-04 1.318276e-03 12 1027748 1027771 24 +      
ENSG00000082805 E025 26.0143582 0.0038999633 1.052834e-06 8.696210e-06 12 1027772 1027841 70 +      
ENSG00000082805 E026 83.7703445 0.0077125595 2.972618e-09 4.036364e-08 12 1027842 1028338 497 +      
ENSG00000082805 E027 64.5500167 0.0122351618 1.557197e-03 5.820388e-03 12 1028339 1028572 234 +      
ENSG00000082805 E028 0.0000000       12 1083141 1083163 23 +      
ENSG00000082805 E029 20.6653752 0.0239749294 2.482220e-02 6.151067e-02 12 1083164 1083172 9 +      
ENSG00000082805 E030 77.2924401 0.0036788253 1.717271e-05 1.081232e-04 12 1083173 1083483 311 +      
ENSG00000082805 E031 45.1968664 0.0031203671 3.033858e-03 1.036585e-02 12 1083484 1083580 97 +      
ENSG00000082805 E032 37.5477909 0.0116442203 1.127206e-02 3.181221e-02 12 1104750 1104824 75 +      
ENSG00000082805 E033 47.5077044 0.0188081030 1.326642e-01 2.378066e-01 12 1110192 1110347 156 +      
ENSG00000082805 E034 10.2565207 0.0843799750 3.518541e-01 4.960573e-01 12 1112215 1112232 18 +      
ENSG00000082805 E035 18.9191243 0.0736331012 2.042208e-01 3.314516e-01 12 1112233 1112298 66 +      
ENSG00000082805 E036 0.9901831 0.0151033080 5.079494e-01 6.433829e-01 12 1112299 1112307 9 +      
ENSG00000082805 E037 0.1515154 0.0424082633 5.494566e-01   12 1115624 1115865 242 +      
ENSG00000082805 E038 31.7379270 0.0192886830 2.936979e-01 4.347450e-01 12 1115866 1115911 46 +      
ENSG00000082805 E039 46.5185042 0.0004938996 2.129787e-02 5.421612e-02 12 1115912 1116033 122 +      
ENSG00000082805 E040 0.1817044 0.0382619011 4.337212e-01   12 1116034 1116201 168 +      
ENSG00000082805 E041 0.1515154 0.0424082633 5.494566e-01   12 1141292 1141454 163 +      
ENSG00000082805 E042 58.3985622 0.0004537752 6.984670e-06 4.812077e-05 12 1141620 1141787 168 +      
ENSG00000082805 E043 0.1482932 0.0421300496 4.330983e-01   12 1141788 1142195 408 +      
ENSG00000082805 E044 0.2987644 0.0293856414 2.374401e-01   12 1168013 1168046 34 +      
ENSG00000082805 E045 58.4298822 0.0003894467 8.046022e-09 1.009122e-07 12 1180540 1180677 138 +      
ENSG00000082805 E046 55.4855410 0.0013212600 1.816302e-10 3.065417e-09 12 1181925 1182065 141 +      
ENSG00000082805 E047 57.9825726 0.0004344926 9.750566e-09 1.204889e-07 12 1183281 1183421 141 +      
ENSG00000082805 E048 0.0000000       12 1183422 1184122 701 +      
ENSG00000082805 E049 0.0000000       12 1188373 1188497 125 +      
ENSG00000082805 E050 38.1692036 0.0006748508 1.903836e-02 4.941919e-02 12 1189859 1189895 37 +      
ENSG00000082805 E051 73.7136918 0.0003799786 5.646576e-06 3.971217e-05 12 1189896 1190052 157 +      
ENSG00000082805 E052 0.0000000       12 1190053 1190375 323 +      
ENSG00000082805 E053 0.0000000       12 1203966 1204096 131 +      
ENSG00000082805 E054 4.8244286 0.0053640137 5.651679e-01 6.923200e-01 12 1204501 1204512 12 +      
ENSG00000082805 E055 67.8385046 0.0009526252 1.473720e-04 7.358387e-04 12 1236769 1236904 136 +      
ENSG00000082805 E056 1.4727006 0.6999668009 9.164442e-01 9.511834e-01 12 1244543 1245024 482 +      
ENSG00000082805 E057 0.0000000       12 1257138 1257237 100 +      
ENSG00000082805 E058 54.6051429 0.0011612379 6.569000e-04 2.740898e-03 12 1263034 1263165 132 +      
ENSG00000082805 E059 42.6657762 0.0075360318 2.639832e-02 6.474229e-02 12 1289852 1289881 30 +      
ENSG00000082805 E060 54.2659785 0.0014090345 7.472714e-02 1.510949e-01 12 1289882 1289975 94 +      
ENSG00000082805 E061 40.5115333 0.0005653688 2.256541e-02 5.685454e-02 12 1289976 1290012 37 +      
ENSG00000082805 E062 57.0682778 0.0004531945 6.183426e-03 1.909771e-02 12 1371833 1371977 145 +      
ENSG00000082805 E063 0.3289534 0.0278799450 9.309986e-01   12 1399660 1399822 163 +      
ENSG00000082805 E064 35.0036480 0.0011997135 1.142149e-02 3.216590e-02 12 1408149 1408191 43 +      
ENSG00000082805 E065 32.0214400 0.0006474206 6.824597e-04 2.834995e-03 12 1408192 1408247 56 +      
ENSG00000082805 E066 0.4720498 0.1620433981 6.788255e-01 7.831953e-01 12 1410389 1410453 65 +      
ENSG00000082805 E067 0.1472490 0.0427770688 5.495824e-01   12 1417974 1418344 371 +      
ENSG00000082805 E068 0.0000000       12 1430277 1430798 522 +      
ENSG00000082805 E069 0.1515154 0.0424082633 5.494566e-01   12 1443291 1444561 1271 +      
ENSG00000082805 E070 59.7135802 0.0004282727 2.785254e-07 2.594317e-06 12 1444562 1444750 189 +      
ENSG00000082805 E071 0.0000000       12 1444751 1445055 305 +      
ENSG00000082805 E072 0.3729606 0.0262099068 9.262991e-01 9.575978e-01 12 1480843 1480898 56 +      
ENSG00000082805 E073 1381.1332734 0.0128963697 4.353922e-13 1.132552e-11 12 1490093 1495933 5841 +