ENSG00000082014

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262188 ENSG00000082014 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCD3 protein_coding protein_coding 28.50053 50.22165 18.57559 2.419267 0.2754191 -1.434412 2.098332 5.092138 0.5980668 0.6466758 0.3051528 -3.0688002 0.06137083 0.1006333 0.03260000 -0.06803333 3.931769e-01 1.692343e-08 FALSE TRUE
ENST00000356800 ENSG00000082014 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCD3 protein_coding protein_coding 28.50053 50.22165 18.57559 2.419267 0.2754191 -1.434412 16.097591 32.176215 9.0920941 1.0193961 0.3735772 -1.8221725 0.53968333 0.6419667 0.48910000 -0.15286667 1.380258e-04 1.692343e-08 FALSE TRUE
ENST00000392811 ENSG00000082014 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCD3 protein_coding protein_coding 28.50053 50.22165 18.57559 2.419267 0.2754191 -1.434412 2.608200 5.057658 1.6764830 0.6042143 0.1269074 -1.5873013 0.07930417 0.1000667 0.09026667 -0.00980000 8.094601e-01 1.692343e-08 FALSE TRUE
ENST00000470588 ENSG00000082014 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCD3 protein_coding retained_intron 28.50053 50.22165 18.57559 2.419267 0.2754191 -1.434412 1.996584 1.678724 1.8950656 0.2133647 0.1132939 0.1739074 0.08672083 0.0333000 0.10200000 0.06870000 1.692343e-08 1.692343e-08 FALSE TRUE
ENST00000485610 ENSG00000082014 HEK293_OSMI2_2hA HEK293_TMG_2hB SMARCD3 protein_coding retained_intron 28.50053 50.22165 18.57559 2.419267 0.2754191 -1.434412 1.562885 1.049517 1.8955579 0.2145663 0.2714019 0.8468073 0.06963333 0.0206000 0.10220000 0.08160000 5.293382e-07 1.692343e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000082014 E001 0.0000000       7 151238764 151238779 16 -      
ENSG00000082014 E002 0.3299976 0.0274424043 8.780671e-01   7 151238780 151238972 193 - 0.000 0.129 8.585
ENSG00000082014 E003 0.6663248 0.0789162138 3.670009e-01 5.113649e-01 7 151238973 151238973 1 - 0.000 0.227 11.307
ENSG00000082014 E004 1.6209171 0.0089841798 6.553141e-02 1.359237e-01 7 151238974 151238975 2 - 0.000 0.408 13.120
ENSG00000082014 E005 2.9409960 0.0054310434 2.664011e-01 4.045765e-01 7 151238976 151238980 5 - 0.347 0.555 1.082
ENSG00000082014 E006 19.5438754 0.0009428097 6.035491e-02 1.272133e-01 7 151238981 151239005 25 - 1.057 1.241 0.658
ENSG00000082014 E007 21.3968363 0.0009175003 1.542786e-01 2.674734e-01 7 151239006 151239007 2 - 1.142 1.270 0.456
ENSG00000082014 E008 31.8782203 0.0030377536 8.237960e-02 1.632657e-01 7 151239008 151239017 10 - 1.301 1.438 0.478
ENSG00000082014 E009 66.1364629 0.0005308582 8.833378e-04 3.555932e-03 7 151239018 151239050 33 - 1.563 1.750 0.635
ENSG00000082014 E010 74.1827534 0.0020540171 5.788616e-03 1.805727e-02 7 151239051 151239062 12 - 1.642 1.795 0.519
ENSG00000082014 E011 218.1638660 0.0036375978 3.287116e-05 1.936483e-04 7 151239063 151239156 94 - 2.089 2.262 0.579
ENSG00000082014 E012 3.9781084 0.0311460471 1.463018e-01 2.566555e-01 7 151239157 151239395 239 - 0.814 0.573 -1.009
ENSG00000082014 E013 295.2735694 0.0003108078 2.052410e-10 3.431193e-09 7 151239396 151239497 102 - 2.221 2.392 0.569
ENSG00000082014 E014 8.2133334 0.0020401559 6.618138e-01 7.702101e-01 7 151239498 151239623 126 - 0.922 0.859 -0.240
ENSG00000082014 E015 399.3575949 0.0001491852 1.127964e-05 7.404342e-05 7 151239624 151239746 123 - 2.417 2.509 0.305
ENSG00000082014 E016 447.4917891 0.0001863593 6.561388e-03 2.008589e-02 7 151240112 151240247 136 - 2.500 2.550 0.167
ENSG00000082014 E017 27.0930564 0.0007574243 1.711909e-07 1.662402e-06 7 151240248 151240421 174 - 1.617 1.241 -1.298
ENSG00000082014 E018 8.1457482 0.0055444274 1.751730e-04 8.576304e-04 7 151240422 151240424 3 - 1.179 0.727 -1.700
ENSG00000082014 E019 318.6335447 0.0002237339 3.742583e-01 5.186809e-01 7 151240425 151240522 98 - 2.385 2.400 0.049
ENSG00000082014 E020 37.6376257 0.0137213987 1.160024e-09 1.698323e-08 7 151240523 151240899 377 - 1.831 1.342 -1.673
ENSG00000082014 E021 24.9668538 0.0135280389 4.262182e-11 8.000966e-10 7 151240900 151241163 264 - 1.704 1.120 -2.025
ENSG00000082014 E022 17.1772464 0.0335160967 1.240394e-03 4.777847e-03 7 151241164 151241257 94 - 1.447 1.055 -1.382
ENSG00000082014 E023 23.2849828 0.0009253631 2.793899e-10 4.569591e-09 7 151241258 151241394 137 - 1.617 1.145 -1.640
ENSG00000082014 E024 16.3967877 0.0092315695 7.669443e-12 1.627594e-10 7 151241395 151241491 97 - 1.570 0.926 -2.281
ENSG00000082014 E025 324.4814822 0.0001887247 3.657320e-02 8.466237e-02 7 151241492 151241653 162 - 2.369 2.413 0.147
ENSG00000082014 E026 15.8253805 0.0182234692 4.410541e-07 3.943943e-06 7 151241654 151241798 145 - 1.492 0.955 -1.906
ENSG00000082014 E027 8.4314169 0.0159633378 5.997670e-06 4.195968e-05 7 151241799 151241876 78 - 1.259 0.698 -2.104
ENSG00000082014 E028 137.6903852 0.0002367497 6.504675e-03 1.993418e-02 7 151241877 151241907 31 - 1.953 2.051 0.329
ENSG00000082014 E029 131.1441589 0.0002880491 3.075367e-02 7.342951e-02 7 151241908 151241936 29 - 1.950 2.028 0.261
ENSG00000082014 E030 160.4966393 0.0013173449 9.627920e-01 9.804871e-01 7 151241937 151241957 21 - 2.102 2.097 -0.016
ENSG00000082014 E031 175.9589852 0.0004160420 3.447761e-01 4.888725e-01 7 151241958 151241978 21 - 2.117 2.142 0.083
ENSG00000082014 E032 279.3144651 0.0007935786 3.825465e-01 5.267493e-01 7 151242137 151242232 96 - 2.322 2.341 0.062
ENSG00000082014 E033 2.3563336 0.0061851806 5.502794e-03 1.729522e-02 7 151242233 151242464 232 - 0.771 0.309 -2.238
ENSG00000082014 E034 2.5817294 0.2706351825 3.357056e-01 4.795056e-01 7 151242465 151242480 16 - 0.669 0.429 -1.120
ENSG00000082014 E035 334.4272483 0.0001545460 8.142381e-02 1.617861e-01 7 151242481 151242603 123 - 2.454 2.407 -0.158
ENSG00000082014 E036 0.1472490 0.0428165103 1.290821e-01   7 151242705 151242720 16 - 0.207 0.000 -12.577
ENSG00000082014 E037 236.2955382 0.0001810563 1.089960e-05 7.179505e-05 7 151242721 151242843 123 - 2.365 2.241 -0.415
ENSG00000082014 E038 98.3381375 0.0048263569 3.332041e-04 1.513088e-03 7 151243659 151243701 43 - 2.041 1.850 -0.641
ENSG00000082014 E039 153.8870978 0.0044310032 1.037853e-02 2.969123e-02 7 151245460 151245671 212 - 2.177 2.056 -0.406
ENSG00000082014 E040 6.2104650 0.0031693795 5.952593e-06 4.166793e-05 7 151245978 151246149 172 - 1.161 0.595 -2.197
ENSG00000082014 E041 49.6077836 0.0048775613 3.742281e-04 1.674415e-03 7 151248485 151248694 210 - 1.772 1.539 -0.791
ENSG00000082014 E042 0.0000000       7 151254295 151254478 184 -      
ENSG00000082014 E043 76.6764279 0.0089998466 5.365059e-01 6.682585e-01 7 151275114 151275251 138 - 1.815 1.772 -0.146
ENSG00000082014 E044 0.3268771 0.0294739321 3.642730e-01   7 151275252 151275252 1 - 0.207 0.069 -1.824
ENSG00000082014 E045 0.0000000       7 151276705 151276734 30 -      
ENSG00000082014 E046 40.7797633 0.0022652320 8.405344e-01 9.004717e-01 7 151277077 151277452 376 - 1.524 1.504 -0.071
ENSG00000082014 E047 0.0000000       7 151277800 151277896 97 -