ENSG00000079950

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367937 ENSG00000079950 HEK293_OSMI2_2hA HEK293_TMG_2hB STX7 protein_coding protein_coding 9.167718 4.320424 14.77486 0.4690585 0.6265562 1.771541 1.077744 0.3127279 0.7699284 0.1351967 0.38565066 1.273023 0.1369542 0.06786667 0.0524000 -0.01546667 0.79597667 0.01620218 FALSE TRUE
MSTRG.28968.2 ENSG00000079950 HEK293_OSMI2_2hA HEK293_TMG_2hB STX7 protein_coding   9.167718 4.320424 14.77486 0.4690585 0.6265562 1.771541 1.999626 1.3363194 3.0203273 0.1190165 0.43072272 1.170453 0.2469875 0.31070000 0.2045000 -0.10620000 0.14984504 0.01620218 TRUE TRUE
MSTRG.28968.3 ENSG00000079950 HEK293_OSMI2_2hA HEK293_TMG_2hB STX7 protein_coding   9.167718 4.320424 14.77486 0.4690585 0.6265562 1.771541 2.872059 1.5035467 4.5015889 0.2193493 0.09598195 1.575702 0.3164917 0.34716667 0.3052667 -0.04190000 0.58999111 0.01620218 TRUE TRUE
MSTRG.28968.4 ENSG00000079950 HEK293_OSMI2_2hA HEK293_TMG_2hB STX7 protein_coding   9.167718 4.320424 14.77486 0.4690585 0.6265562 1.771541 2.864553 0.9224147 6.0763347 0.1094423 0.47362938 2.706530 0.2660792 0.22143333 0.4102333 0.18880000 0.01620218 0.01620218 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000079950 E001 28.3481648 0.0007646763 0.90810494 0.94566009 6 132445867 132455974 10108 - 1.439 1.429 -0.037
ENSG00000079950 E002 1.1134841 0.0118752825 0.39078943 0.53473760 6 132455975 132455978 4 - 0.256 0.412 0.977
ENSG00000079950 E003 3.2652121 0.0101992551 0.57843709 0.70352504 6 132455979 132456221 243 - 0.581 0.671 0.390
ENSG00000079950 E004 4.7883946 0.0152366556 0.15753003 0.27182926 6 132456222 132457276 1055 - 0.794 0.561 -0.986
ENSG00000079950 E005 175.4293350 0.0002694276 0.40563003 0.54929656 6 132457277 132459527 2251 - 2.212 2.232 0.068
ENSG00000079950 E006 23.7013010 0.0009920326 0.46584703 0.60545764 6 132459528 132459569 42 - 1.382 1.323 -0.205
ENSG00000079950 E007 33.6370373 0.0074361649 0.85804696 0.91240533 6 132459570 132459632 63 - 1.507 1.519 0.041
ENSG00000079950 E008 185.6724114 0.0010090840 0.01252734 0.03480067 6 132459633 132460714 1082 - 2.220 2.289 0.229
ENSG00000079950 E009 59.7555452 0.0004959516 0.01274166 0.03530339 6 132460715 132460850 136 - 1.714 1.829 0.387
ENSG00000079950 E010 2.4721460 0.0591854481 0.06152064 0.12919067 6 132461714 132461860 147 - 0.381 0.717 1.585
ENSG00000079950 E011 56.4328436 0.0004105854 0.23287983 0.36584835 6 132463993 132464075 83 - 1.711 1.767 0.189
ENSG00000079950 E012 56.3938761 0.0008045614 0.61658005 0.73461697 6 132468403 132468475 73 - 1.721 1.743 0.074
ENSG00000079950 E013 48.7446462 0.0005285505 0.69583230 0.79631839 6 132469951 132469993 43 - 1.663 1.681 0.061
ENSG00000079950 E014 61.3754136 0.0004082217 0.80382382 0.87518703 6 132469994 132470047 54 - 1.765 1.775 0.032
ENSG00000079950 E015 60.1072559 0.0004678611 0.73055062 0.82246495 6 132470574 132470626 53 - 1.756 1.771 0.049
ENSG00000079950 E016 104.6924996 0.0003426975 0.13036328 0.23466580 6 132471463 132471600 138 - 2.015 1.957 -0.196
ENSG00000079950 E017 84.3092702 0.0003774492 0.05200302 0.11272617 6 132472282 132472375 94 - 1.929 1.845 -0.282
ENSG00000079950 E018 0.2955422 0.0282556766 0.47701666   6 132475280 132475592 313 - 0.080 0.184 1.385
ENSG00000079950 E019 64.0542554 0.0084298876 0.13177333 0.23659254 6 132475593 132475662 70 - 1.815 1.714 -0.343
ENSG00000079950 E020 59.1632742 0.0078327752 0.18439406 0.30674647 6 132503446 132503514 69 - 1.778 1.680 -0.331
ENSG00000079950 E021 51.9290554 0.0005119203 0.36481563 0.50915139 6 132503515 132503588 74 - 1.708 1.656 -0.175
ENSG00000079950 E022 39.0011471 0.0143550665 0.55049517 0.68012038 6 132513007 132513057 51 - 1.586 1.524 -0.212
ENSG00000079950 E023 21.4938540 0.0271696796 0.08088220 0.16091924 6 132513058 132513198 141 - 1.375 1.156 -0.769