ENSG00000079805

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-6 / 6
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000359692	ENSG00000079805	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DNM2	protein_coding	protein_coding	101.0475	157.9901	68.48812	8.824976	0.5870472	-1.205789	46.171340	76.073240	29.083984	7.9784144	1.060841	-1.3868578	0.43927083	0.4787667	0.42460000	-0.05416667	4.404364e-01	1.286974e-23	FALSE	TRUE
ENST00000408974	ENSG00000079805	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DNM2	protein_coding	protein_coding	101.0475	157.9901	68.48812	8.824976	0.5870472	-1.205789	13.817182	22.371958	11.137339	1.7228189	1.771310	-1.0056369	0.14792917	0.1433667	0.16293333	0.01956667	8.608082e-01	1.286974e-23	FALSE	TRUE
ENST00000585892	ENSG00000079805	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DNM2	protein_coding	protein_coding	101.0475	157.9901	68.48812	8.824976	0.5870472	-1.205789	12.164715	23.294125	5.490878	1.0484200	1.003533	-2.0828515	0.10765833	0.1476333	0.08046667	-0.06716667	2.382216e-02	1.286974e-23	FALSE	TRUE
ENST00000591818	ENSG00000079805	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DNM2	protein_coding	protein_coding	101.0475	157.9901	68.48812	8.824976	0.5870472	-1.205789	2.364432	7.882638	0.000000	0.8684195	0.000000	-9.6243638	0.01566250	0.0509000	0.00000000	-0.05090000	1.286974e-23	1.286974e-23	FALSE	FALSE
MSTRG.16425.10	ENSG00000079805	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DNM2	protein_coding		101.0475	157.9901	68.48812	8.824976	0.5870472	-1.205789	1.541289	0.000000	3.574161	0.0000000	1.895968	8.4854918	0.02195417	0.0000000	0.05173333	0.05173333	1.202372e-01	1.286974e-23	FALSE	TRUE
MSTRG.16425.3	ENSG00000079805	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DNM2	protein_coding		101.0475	157.9901	68.48812	8.824976	0.5870472	-1.205789	14.099839	18.150120	11.617052	1.3065285	0.323863	-0.6432883	0.14961667	0.1147000	0.16956667	0.05486667	5.440926e-07	1.286974e-23	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000079805	E001	1.0621005	0.0140079857	4.866372e-01	6.243529e-01	19	10717958	10717991	34	+	0.176	0.314	1.091
ENSG00000079805	E002	1.8725669	0.0474831363	9.095880e-01	9.465474e-01	19	10717992	10718000	9	+	0.397	0.431	0.184
ENSG00000079805	E003	5.7425169	0.0028945994	6.789623e-04	2.822137e-03	19	10718001	10718054	54	+	1.040	0.622	-1.646
ENSG00000079805	E004	11.4537902	0.0017736416	1.054253e-09	1.556704e-08	19	10718055	10718078	24	+	1.379	0.800	-2.111
ENSG00000079805	E005	15.8645645	0.0091078000	2.400003e-13	6.467615e-12	19	10718079	10718091	13	+	1.549	0.869	-2.426
ENSG00000079805	E006	17.4897280	0.0035539404	2.758103e-18	1.437453e-16	19	10718092	10718092	1	+	1.606	0.880	-2.579
ENSG00000079805	E007	170.7027294	0.0370908312	1.352288e-03	5.150520e-03	19	10718093	10718207	115	+	2.362	2.087	-0.918
ENSG00000079805	E008	477.2923836	0.0125633361	1.044208e-02	2.984328e-02	19	10718208	10718403	196	+	2.706	2.589	-0.390
ENSG00000079805	E009	0.3299976	0.0274424043	5.719565e-01		19	10718561	10718646	86	+	0.000	0.154	9.497
ENSG00000079805	E010	0.0000000				19	10755121	10755488	368	+
ENSG00000079805	E011	1.0391862	0.4193752464	4.490832e-01	5.902910e-01	19	10759634	10759737	104	+	0.398	0.255	-0.910
ENSG00000079805	E012	424.4862683	0.0042423467	2.258279e-02	5.688470e-02	19	10759738	10759811	74	+	2.615	2.554	-0.204
ENSG00000079805	E013	0.0000000				19	10763099	10763616	518	+
ENSG00000079805	E014	0.0000000				19	10768553	10768862	310	+
ENSG00000079805	E015	0.0000000				19	10769289	10769446	158	+
ENSG00000079805	E016	790.1608200	0.0018553120	5.908325e-10	9.143979e-09	19	10772479	10772628	150	+	2.934	2.802	-0.437
ENSG00000079805	E017	1080.8894122	0.0004438521	7.374961e-28	1.032642e-25	19	10775703	10775906	204	+	3.077	2.933	-0.481
ENSG00000079805	E018	564.1325600	0.0004232846	6.275097e-15	2.131227e-13	19	10777118	10777168	51	+	2.783	2.656	-0.422
ENSG00000079805	E019	611.4462273	0.0008901187	1.519794e-07	1.490580e-06	19	10777169	10777216	48	+	2.793	2.702	-0.303
ENSG00000079805	E020	0.4031496	0.0245318877	5.695232e-01	6.960753e-01	19	10781374	10781567	194	+	0.000	0.154	9.502
ENSG00000079805	E021	0.0000000				19	10781568	10781795	228	+
ENSG00000079805	E022	629.3447221	0.0004965419	2.552962e-09	3.509804e-08	19	10782960	10783015	56	+	2.806	2.714	-0.305
ENSG00000079805	E023	746.4930288	0.0011032667	9.534167e-07	7.942917e-06	19	10783016	10783120	105	+	2.875	2.791	-0.278
ENSG00000079805	E024	0.8783198	0.0133878929	6.497424e-01	7.608946e-01	19	10786430	10786563	134	+	0.176	0.267	0.769
ENSG00000079805	E025	879.4390813	0.0010164576	3.372625e-04	1.529391e-03	19	10786564	10786706	143	+	2.923	2.872	-0.171
ENSG00000079805	E026	1.0394002	0.3704886690	5.107267e-01	6.459075e-01	19	10786707	10786741	35	+	0.399	0.219	-1.203
ENSG00000079805	E027	850.2849407	0.0013160036	1.097988e-02	3.111369e-02	19	10793720	10793855	136	+	2.898	2.862	-0.117
ENSG00000079805	E028	1.6134561	0.1395694087	2.249236e-01	3.563337e-01	19	10793856	10794734	879	+	0.176	0.457	1.904
ENSG00000079805	E029	704.0234025	0.0001201944	3.031823e-07	2.802898e-06	19	10795372	10795439	68	+	2.831	2.770	-0.204
ENSG00000079805	E030	31.7885121	0.0385948992	4.264640e-02	9.590024e-02	19	10795440	10795715	276	+	1.607	1.390	-0.744
ENSG00000079805	E031	40.1625828	0.0006329001	1.406191e-04	7.061406e-04	19	10795716	10796060	345	+	1.694	1.488	-0.702
ENSG00000079805	E032	610.6882176	0.0007959944	7.929380e-01	8.675950e-01	19	10796061	10796199	139	+	2.707	2.732	0.082
ENSG00000079805	E033	242.8128400	0.0008094509	1.441676e-43	6.151377e-41	19	10797380	10797518	139	+	2.559	2.208	-1.172
ENSG00000079805	E034	4.8746027	0.0034228754	1.786289e-02	4.684290e-02	19	10798387	10798485	99	+	0.929	0.622	-1.233
ENSG00000079805	E035	793.1952256	0.0009027033	2.303243e-05	1.407738e-04	19	10798486	10798572	87	+	2.888	2.823	-0.214
ENSG00000079805	E036	834.8722395	0.0001100309	1.369854e-03	5.208390e-03	19	10802288	10802358	71	+	2.883	2.854	-0.094
ENSG00000079805	E037	30.5539739	0.0045773705	1.176029e-08	1.431362e-07	19	10802359	10803638	1280	+	1.689	1.304	-1.322
ENSG00000079805	E038	4.5620821	0.0292269493	2.856593e-02	6.914181e-02	19	10803639	10803668	30	+	0.902	0.578	-1.327
ENSG00000079805	E039	27.1962600	0.0008309894	7.414211e-10	1.127197e-08	19	10803669	10804912	1244	+	1.647	1.250	-1.371
ENSG00000079805	E040	34.6666321	0.0008757045	1.778308e-06	1.398660e-05	19	10804980	10805915	936	+	1.685	1.409	-0.945
ENSG00000079805	E041	770.8219037	0.0004516231	2.482445e-01	3.838583e-01	19	10805916	10805967	52	+	2.831	2.829	-0.006
ENSG00000079805	E042	11.1726187	0.0015319155	5.753979e-01	7.010077e-01	19	10808519	10808568	50	+	1.060	1.015	-0.165
ENSG00000079805	E043	149.0912518	0.0002288569	1.784763e-02	4.680676e-02	19	10808569	10808580	12	+	2.042	2.139	0.325
ENSG00000079805	E044	22.4374910	0.0009610636	3.308281e-01	4.743928e-01	19	10808581	10809207	627	+	1.351	1.290	-0.214
ENSG00000079805	E045	143.4854882	0.0034428291	9.817455e-01	9.926335e-01	19	10809208	10812263	3056	+	2.082	2.103	0.070
ENSG00000079805	E046	1002.1197282	0.0005480091	5.150429e-01	6.497583e-01	19	10812264	10812377	114	+	2.938	2.946	0.026
ENSG00000079805	E047	1111.6500949	0.0003707729	6.179870e-02	1.296535e-01	19	10819980	10820089	110	+	2.953	2.999	0.153
ENSG00000079805	E048	3.1497700	0.0675217110	5.731826e-01	6.991676e-01	19	10823224	10823787	564	+	0.476	0.601	0.586
ENSG00000079805	E049	1205.2976840	0.0002303588	2.034062e-02	5.219807e-02	19	10823788	10823899	112	+	2.986	3.035	0.162
ENSG00000079805	E050	4.7469138	0.0094920802	3.619258e-02	8.395260e-02	19	10823900	10824806	907	+	0.397	0.771	1.711
ENSG00000079805	E051	1443.6931096	0.0014448089	8.305126e-02	1.643289e-01	19	10825057	10825221	165	+	3.060	3.116	0.186
ENSG00000079805	E052	910.0575255	0.0018609275	3.843743e-02	8.817005e-02	19	10829036	10829111	76	+	2.848	2.919	0.238
ENSG00000079805	E053	1126.7082488	0.0026744532	6.649555e-06	4.603297e-05	19	10829112	10829268	157	+	2.883	3.028	0.482
ENSG00000079805	E054	1159.0740789	0.0023066090	1.047531e-13	2.967722e-12	19	10830127	10830337	211	+	2.837	3.053	0.720
ENSG00000079805	E055	582.5286994	0.0003750625	2.060885e-18	1.092108e-16	19	10830338	10830378	41	+	2.555	2.747	0.641
ENSG00000079805	E056	6.8600494	0.0024433498	4.743888e-02	1.046150e-01	19	10830379	10830534	156	+	0.999	0.770	-0.878
ENSG00000079805	E057	299.8196759	0.0005478998	9.863287e-16	3.725220e-14	19	10830978	10830980	3	+	2.227	2.466	0.800
ENSG00000079805	E058	2587.0570467	0.0012269346	1.058096e-50	6.726615e-48	19	10830981	10831903	923	+	3.122	3.415	0.975
ENSG00000079805	E059	452.9464755	0.0003582397	2.815985e-03	9.721375e-03	19	10832304	10832991	688	+	2.537	2.617	0.267
ENSG00000079805	E060	303.2964175	0.0014573871	3.286526e-08	3.671989e-07	19	10832992	10833488	497	+	2.279	2.468	0.630

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000079805

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3