ENSG00000079482

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-4 / 4
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC

ENST00000355520	ENSG00000079482	HEK293_OSMI2_2hA	HEK293_TMG_2hB	OPHN1	protein_coding	protein_coding	2.354072	1.758728	2.892511	0.1695193	0.1228261	0.7145898	1.32740501	0.9563936	1.4111043	0.06826734	0.11272312	0.5563297	0.58904167	0.5482000	0.49030000	-0.05790000	0.746836627	0.002139102	FALSE
ENST00000491714	ENSG00000079482	HEK293_OSMI2_2hA	HEK293_TMG_2hB	OPHN1	protein_coding	protein_coding	2.354072	1.758728	2.892511	0.1695193	0.1228261	0.7145898	0.21073438	0.3260563	0.2777830	0.07266638	0.06376956	-0.2237218	0.09038333	0.1817333	0.09763333	-0.08410000	0.302847679	0.002139102
ENST00000680262	ENSG00000079482	HEK293_OSMI2_2hA	HEK293_TMG_2hB	OPHN1	protein_coding	processed_transcript	2.354072	1.758728	2.892511	0.1695193	0.1228261	0.7145898	0.24623166	0.2635284	0.5238613	0.06131205	0.08717648	0.9647744	0.10638750	0.1535667	0.17923333	0.02566667	0.812064014	0.002139102
ENST00000681408	ENSG00000079482	HEK293_OSMI2_2hA	HEK293_TMG_2hB	OPHN1	protein_coding	protein_coding	2.354072	1.758728	2.892511	0.1695193	0.1228261	0.7145898	0.05754549	0.0000000	0.1887958	0.00000000	0.01082388	4.3132155	0.01974583	0.0000000	0.06520000	0.06520000	0.002139102	0.002139102	FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 50
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000079482	E001	0.0000000				X	67949349	67949585	237	-
ENSG00000079482	E002	16.6621031	0.0761447897	5.182014e-03	1.642409e-02	X	68042344	68043463	1120	-	0.994	1.463	1.661
ENSG00000079482	E003	77.7569007	0.0043320641	6.560168e-10	1.006971e-08	X	68043464	68045130	1667	-	1.747	2.044	1.000
ENSG00000079482	E004	41.5265544	0.0006708999	4.399191e-01	5.816467e-01	X	68045131	68046274	1144	-	1.592	1.660	0.231
ENSG00000079482	E005	8.5511101	0.0020788416	4.320187e-01	5.744839e-01	X	68046275	68046397	123	-	0.994	0.930	-0.236
ENSG00000079482	E006	24.6769934	0.0007670343	9.369349e-02	1.808931e-01	X	68046398	68046906	509	-	1.437	1.347	-0.311
ENSG00000079482	E007	14.8868180	0.0013895215	3.013599e-01	4.431486e-01	X	68046907	68047163	257	-	1.219	1.154	-0.230
ENSG00000079482	E008	4.8418711	0.0099637739	2.799803e-01	4.197843e-01	X	68048416	68048457	42	-	0.684	0.857	0.693
ENSG00000079482	E009	0.0000000				X	68048458	68048582	125	-
ENSG00000079482	E010	6.0703521	0.0031885788	4.929681e-01	6.300544e-01	X	68052540	68052590	51	-	0.797	0.907	0.426
ENSG00000079482	E011	6.9403441	0.0353008091	7.726205e-01	8.532376e-01	X	68053645	68053810	166	-	0.900	0.883	-0.063
ENSG00000079482	E012	9.4529284	0.0031012246	2.891332e-01	4.298100e-01	X	68063854	68064177	324	-	1.044	0.952	-0.337
ENSG00000079482	E013	7.8614010	0.0042944956	7.080401e-01	8.057652e-01	X	68073152	68073299	148	-	0.949	0.930	-0.071
ENSG00000079482	E014	8.8875325	0.0020130764	9.252727e-04	3.703495e-03	X	68096870	68097029	160	-	1.105	0.734	-1.408
ENSG00000079482	E015	8.4637815	0.0022521756	5.934095e-03	1.843513e-02	X	68111854	68111959	106	-	1.071	0.768	-1.148
ENSG00000079482	E016	0.0000000				X	68112387	68112422	36	-
ENSG00000079482	E017	5.7540500	0.0029507863	8.947852e-02	1.743346e-01	X	68113181	68113239	59	-	0.900	0.697	-0.804
ENSG00000079482	E018	7.0428071	0.0025090002	5.684106e-01	6.951011e-01	X	68119248	68119332	85	-	0.925	0.882	-0.163
ENSG00000079482	E019	0.3634088	0.2724650368	1.337325e-01		X	68192742	68192918	177	-	0.000	0.276	12.301
ENSG00000079482	E020	7.8137216	0.0022564573	3.266656e-01	4.701069e-01	X	68192919	68192993	75	-	0.972	0.883	-0.337
ENSG00000079482	E021	7.8544695	0.0035952663	6.064925e-02	1.277228e-01	X	68193890	68193952	63	-	1.004	0.800	-0.777
ENSG00000079482	E022	6.5958247	0.0025832539	1.542048e-01	2.673884e-01	X	68194465	68194498	34	-	0.925	0.768	-0.609
ENSG00000079482	E023	8.4038254	0.0023834911	2.390634e-02	5.961229e-02	X	68197186	68197264	79	-	1.044	0.800	-0.921
ENSG00000079482	E024	8.2327553	0.0020061376	6.100167e-02	1.283195e-01	X	68201619	68201710	92	-	1.024	0.829	-0.736
ENSG00000079482	E025	8.7907563	0.0020924882	6.514216e-02	1.352748e-01	X	68206573	68206673	101	-	1.044	0.857	-0.699
ENSG00000079482	E026	1.1135859	0.0122653409	1.940801e-01	3.189084e-01	X	68206674	68207011	338	-	0.387	0.159	-1.698
ENSG00000079482	E027	0.0000000				X	68208048	68208114	67	-
ENSG00000079482	E028	3.0580586	0.0053239220	6.368299e-02	1.328329e-01	X	68208115	68210152	2038	-	0.465	0.768	1.344
ENSG00000079482	E029	10.2948208	0.0054874884	3.857633e-02	8.840969e-02	X	68210153	68210282	130	-	1.113	0.907	-0.758
ENSG00000079482	E030	0.0000000				X	68210283	68212107	1825	-
ENSG00000079482	E031	6.4249449	0.0027572867	1.809578e-02	4.733698e-02	X	68212108	68212212	105	-	0.949	0.657	-1.158
ENSG00000079482	E032	6.9815871	0.0023914695	1.603636e-02	4.281524e-02	X	68213862	68213972	111	-	0.983	0.697	-1.114
ENSG00000079482	E033	0.0000000				X	68233480	68234486	1007	-
ENSG00000079482	E034	6.6688881	0.0043923948	4.504749e-01	5.915662e-01	X	68234487	68234588	102	-	0.900	0.830	-0.271
ENSG00000079482	E035	5.8260677	0.0031438547	3.816965e-01	5.260072e-01	X	68274738	68274809	72	-	0.859	0.768	-0.355
ENSG00000079482	E036	4.5060749	0.0278722536	1.227144e-01	2.238299e-01	X	68283056	68283117	62	-	0.797	0.565	-0.977
ENSG00000079482	E037	5.6059563	0.0062166455	8.951814e-02	1.743958e-01	X	68299001	68299096	96	-	0.873	0.658	-0.866
ENSG00000079482	E038	0.1515154	0.0436194940	8.282395e-01		X	68336429	68336452	24	-	0.093	0.000	-11.457
ENSG00000079482	E039	0.0000000				X	68380493	68380509	17	-
ENSG00000079482	E040	0.0000000				X	68380510	68380911	402	-
ENSG00000079482	E041	0.1472490	0.0431487049	8.285403e-01		X	68380912	68382353	1442	-	0.093	0.000	-11.458
ENSG00000079482	E042	0.1515154	0.0436194940	8.282395e-01		X	68382354	68383154	801	-	0.093	0.000	-11.457
ENSG00000079482	E043	0.1515154	0.0436194940	8.282395e-01		X	68383155	68383984	830	-	0.093	0.000	-11.457
ENSG00000079482	E044	1.1028881	0.0121989077	7.394859e-01	8.291611e-01	X	68411119	68412858	1740	-	0.292	0.367	0.470
ENSG00000079482	E045	1.9122086	0.1698354158	2.536747e-01	3.902388e-01	X	68412859	68413015	157	-	0.342	0.607	1.347
ENSG00000079482	E046	7.4397727	0.0411560056	6.429416e-01	7.556039e-01	X	68430585	68431077	493	-	0.873	0.958	0.322
ENSG00000079482	E047	0.0000000				X	68431906	68432866	961	-
ENSG00000079482	E048	14.0469887	0.0013254879	8.954227e-01	9.372095e-01	X	68432867	68433024	158	-	1.166	1.180	0.052
ENSG00000079482	E049	16.5201777	0.0011816294	3.193012e-01	4.623749e-01	X	68433168	68433630	463	-	1.193	1.301	0.380
ENSG00000079482	E050	3.8919849	0.0286192143	7.776501e-01	8.569155e-01	X	68433631	68433913	283	-	0.684	0.658	-0.111

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000079482

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3