• ENSG00000071051
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000071051

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000233154 ENSG00000071051 HEK293_OSMI2_2hA HEK293_TMG_2hB NCK2 protein_coding protein_coding 19.33412 22.35733 19.82744 0.239752 0.9528393 -0.1731673 10.0382056 10.1237057 12.3505034 0.87182268 0.3593542 0.2865757 0.51982083 0.453233333 0.62733333 0.17410000 9.486384e-02 1.355902e-13 FALSE TRUE
ENST00000393348 ENSG00000071051 HEK293_OSMI2_2hA HEK293_TMG_2hB NCK2 protein_coding protein_coding 19.33412 22.35733 19.82744 0.239752 0.9528393 -0.1731673 1.2079603 0.0000000 0.7574442 0.00000000 0.7574442 6.2619899 0.06465417 0.000000000 0.03493333 0.03493333 8.219602e-01 1.355902e-13 FALSE TRUE
ENST00000393349 ENSG00000071051 HEK293_OSMI2_2hA HEK293_TMG_2hB NCK2 protein_coding protein_coding 19.33412 22.35733 19.82744 0.239752 0.9528393 -0.1731673 1.0934869 3.8956991 0.0000000 0.96082061 0.0000000 -8.6094370 0.05157500 0.173533333 0.00000000 -0.17353333 1.355902e-13 1.355902e-13 FALSE TRUE
ENST00000451463 ENSG00000071051 HEK293_OSMI2_2hA HEK293_TMG_2hB NCK2 protein_coding protein_coding 19.33412 22.35733 19.82744 0.239752 0.9528393 -0.1731673 5.9037410 7.2929705 5.4435229 0.65062126 0.2352866 -0.4212949 0.30866250 0.326200000 0.27466667 -0.05153333 4.481520e-01 1.355902e-13 FALSE TRUE
MSTRG.18979.1 ENSG00000071051 HEK293_OSMI2_2hA HEK293_TMG_2hB NCK2 protein_coding   19.33412 22.35733 19.82744 0.239752 0.9528393 -0.1731673 0.6882816 0.2136806 1.2759701 0.04639823 0.3552989 2.5233449 0.03575833 0.009533333 0.06306667 0.05353333 4.429338e-04 1.355902e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000071051 E001 0.9598804 0.0161318290 6.500304e-02 1.350451e-01 2 105744841 105744895 55 + 0.440 0.115 -2.534
ENSG00000071051 E002 2.2705873 0.1003398566 1.357870e-03 5.169392e-03 2 105744896 105744911 16 + 0.770 0.115 -4.007
ENSG00000071051 E003 14.7711273 0.0143848075 1.224530e-13 3.437812e-12 2 105744912 105745062 151 + 1.493 0.637 -3.175
ENSG00000071051 E004 28.8951084 0.0242324425 9.055535e-06 6.079609e-05 2 105745063 105745138 76 + 1.671 1.221 -1.551
ENSG00000071051 E005 0.3030308 0.3885308748 2.511370e-01   2 105745731 105745887 157 + 0.232 0.000 -9.351
ENSG00000071051 E006 110.1826303 0.0002665116 4.955810e-05 2.795401e-04 2 105816430 105816557 128 + 2.114 1.979 -0.452
ENSG00000071051 E007 128.9288902 0.0002689169 1.737673e-02 4.577012e-02 2 105816558 105816613 56 + 2.150 2.076 -0.247
ENSG00000071051 E008 0.0000000       2 105851748 105851781 34 +      
ENSG00000071051 E009 0.3289534 0.0290521761 9.168622e-01   2 105851782 105851897 116 + 0.130 0.115 -0.214
ENSG00000071051 E010 90.8589804 0.0003178936 1.048855e-02 2.995079e-02 2 105855048 105855050 3 + 2.010 1.915 -0.318
ENSG00000071051 E011 274.0445443 0.0002474056 3.852316e-02 8.831513e-02 2 105855051 105855289 239 + 2.459 2.415 -0.147
ENSG00000071051 E012 406.5408671 0.0002148825 7.592552e-01 8.436481e-01 2 105881328 105882049 722 + 2.602 2.606 0.012
ENSG00000071051 E013 726.8170893 0.0002084192 3.661005e-19 2.122946e-17 2 105892982 105894274 1293 + 2.797 2.895 0.327