ENSG00000068438

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-5 / 5
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000348411	ENSG00000068438	HEK293_OSMI2_2hA	HEK293_TMG_2hB	FTSJ1	protein_coding	protein_coding	54.50053	79.82834	47.26968	1.704701	0.8968907	-0.7558615	27.995539	39.382967	26.212424	1.2183814	0.6307079	-0.5871370	0.51854583	0.49443333	0.55463333	0.06020000	0.3514118103	0.0003944716	FALSE	TRUE
ENST00000466371	ENSG00000068438	HEK293_OSMI2_2hA	HEK293_TMG_2hB	FTSJ1	protein_coding	processed_transcript	54.50053	79.82834	47.26968	1.704701	0.8968907	-0.7558615	8.328371	16.272788	5.138377	1.3688084	0.2164018	-1.6611582	0.13810417	0.20443333	0.10863333	-0.09580000	0.0003944716	0.0003944716	FALSE	TRUE
ENST00000467954	ENSG00000068438	HEK293_OSMI2_2hA	HEK293_TMG_2hB	FTSJ1	protein_coding	processed_transcript	54.50053	79.82834	47.26968	1.704701	0.8968907	-0.7558615	5.182677	6.911308	4.754563	0.5386829	0.4112311	-0.5387008	0.09967083	0.08640000	0.10076667	0.01436667	0.6318311526	0.0003944716	TRUE	FALSE
MSTRG.34199.1	ENSG00000068438	HEK293_OSMI2_2hA	HEK293_TMG_2hB	FTSJ1	protein_coding		54.50053	79.82834	47.26968	1.704701	0.8968907	-0.7558615	2.441279	2.981712	2.401445	0.1263537	0.4683868	-0.3110735	0.05010417	0.03743333	0.05116667	0.01373333	0.6553443248	0.0003944716	FALSE	TRUE
MSTRG.34199.4	ENSG00000068438	HEK293_OSMI2_2hA	HEK293_TMG_2hB	FTSJ1	protein_coding		54.50053	79.82834	47.26968	1.704701	0.8968907	-0.7558615	3.400525	6.087629	2.502052	1.7087056	1.2591518	-1.2793821	0.05593750	0.07603333	0.05210000	-0.02393333	0.8076491021	0.0003944716	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000068438	E001	0.147249	0.0434239866	2.695576e-01		X	48475967	48476020	54	+	0.160	0.000	-9.042
ENSG00000068438	E002	3.578266	0.0045579491	5.310592e-01	6.635640e-01	X	48476021	48476152	132	+	0.566	0.659	0.411
ENSG00000068438	E003	6.244085	0.0318015059	7.139917e-01	8.103352e-01	X	48476153	48476160	8	+	0.861	0.798	-0.245
ENSG00000068438	E004	30.961817	0.0153940132	2.925979e-01	4.335690e-01	X	48476161	48476198	38	+	1.531	1.431	-0.346
ENSG00000068438	E005	32.804281	0.0190913767	4.286714e-01	5.713980e-01	X	48476199	48476202	4	+	1.543	1.462	-0.276
ENSG00000068438	E006	77.417249	0.0117037275	1.219878e-04	6.229170e-04	X	48476203	48476217	15	+	2.019	1.758	-0.879
ENSG00000068438	E007	234.620377	0.0105178043	3.696351e-01	5.140367e-01	X	48476218	48476259	42	+	2.373	2.317	-0.185
ENSG00000068438	E008	424.883029	0.0028487096	1.040944e-01	1.967452e-01	X	48476260	48476396	137	+	2.630	2.574	-0.188
ENSG00000068438	E009	6.814854	0.1092617167	1.285601e-02	3.557910e-02	X	48476563	48476668	106	+	1.131	0.642	-1.888
ENSG00000068438	E010	309.310161	0.0002264247	8.871283e-03	2.595941e-02	X	48477961	48478009	49	+	2.498	2.434	-0.212
ENSG00000068438	E011	477.531364	0.0007272411	3.954782e-01	5.392876e-01	X	48478010	48478168	159	+	2.660	2.635	-0.083
ENSG00000068438	E012	17.201892	0.0015294894	1.756888e-05	1.103571e-04	X	48478169	48478448	280	+	1.437	1.076	-1.269
ENSG00000068438	E013	302.881618	0.0015425017	6.444678e-01	7.567544e-01	X	48478449	48478518	70	+	2.443	2.448	0.017
ENSG00000068438	E014	272.998109	0.0004187196	5.514600e-01	6.809172e-01	X	48478617	48478680	64	+	2.416	2.394	-0.072
ENSG00000068438	E015	215.687737	0.0007758273	2.874349e-01	4.279267e-01	X	48478681	48478707	27	+	2.283	2.306	0.077
ENSG00000068438	E016	293.452271	0.0012586450	4.986643e-02	1.089310e-01	X	48479038	48479116	79	+	2.402	2.449	0.157
ENSG00000068438	E017	190.892908	0.0032907750	2.522371e-01	3.885685e-01	X	48481151	48481164	14	+	2.223	2.261	0.128
ENSG00000068438	E018	220.765301	0.0030507768	5.750131e-02	1.223378e-01	X	48481165	48481203	39	+	2.267	2.330	0.212
ENSG00000068438	E019	243.623507	0.0004995175	4.147715e-02	9.376545e-02	X	48481289	48481342	54	+	2.323	2.369	0.155
ENSG00000068438	E020	281.305998	0.0001699734	7.051280e-02	1.441916e-01	X	48481426	48481481	56	+	2.392	2.427	0.115
ENSG00000068438	E021	290.934978	0.0001622982	8.385839e-03	2.475300e-02	X	48481482	48481528	47	+	2.393	2.446	0.175
ENSG00000068438	E022	28.196327	0.0009276920	8.374744e-01	8.984077e-01	X	48481529	48481631	103	+	1.422	1.429	0.025
ENSG00000068438	E023	352.171746	0.0001777292	1.795845e-03	6.586212e-03	X	48481632	48481715	84	+	2.473	2.531	0.192
ENSG00000068438	E024	143.095623	0.0002288137	8.185768e-01	8.853429e-01	X	48482403	48482408	6	+	2.123	2.123	0.001
ENSG00000068438	E025	218.165085	0.0013157302	6.392199e-01	7.526541e-01	X	48482409	48482419	11	+	2.301	2.309	0.026
ENSG00000068438	E026	354.226607	0.0012921275	5.284795e-01	6.613963e-01	X	48482420	48482506	87	+	2.509	2.520	0.034
ENSG00000068438	E027	574.837672	0.0012203135	8.657636e-02	1.699290e-01	X	48482597	48482794	198	+	2.704	2.736	0.106
ENSG00000068438	E028	175.252209	0.0003534379	5.235796e-07	4.612443e-06	X	48482795	48482985	191	+	2.105	2.251	0.489
ENSG00000068438	E029	236.709336	0.0008023346	4.080009e-02	9.251181e-02	X	48482986	48483027	42	+	2.385	2.323	-0.205
ENSG00000068438	E030	6.171116	0.0031187275	4.239900e-05	2.429559e-04	X	48483241	48483252	12	+	1.100	0.586	-2.025
ENSG00000068438	E031	9.851771	0.0145992244	2.258148e-05	1.382853e-04	X	48483253	48483341	89	+	1.275	0.778	-1.834
ENSG00000068438	E032	743.643197	0.0015238839	6.631600e-03	2.026742e-02	X	48485736	48486364	629	+	2.881	2.816	-0.215

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000068438

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3