ENSG00000052841

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-6 / 6
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000039989	ENSG00000052841	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC17	protein_coding	protein_coding	21.61228	10.38088	26.38333	0.442421	0.1515349	1.344856	4.588850	1.4973468	7.416699	0.4586950	1.1173458	2.300710	0.19386250	0.14276667	0.28090000	0.13813333	2.230403e-01	1.849113e-42	FALSE	TRUE
ENST00000299240	ENSG00000052841	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC17	protein_coding	protein_coding	21.61228	10.38088	26.38333	0.442421	0.1515349	1.344856	3.758917	1.7786297	5.469301	0.2247000	0.1566945	1.615137	0.16725417	0.17210000	0.20726667	0.03516667	5.468351e-01	1.849113e-42	FALSE	TRUE
ENST00000418561	ENSG00000052841	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC17	protein_coding	protein_coding	21.61228	10.38088	26.38333	0.442421	0.1515349	1.344856	1.551201	3.4473991	0.000000	0.4684843	0.0000000	-8.433543	0.12160833	0.32976667	0.00000000	-0.32976667	1.849113e-42	1.849113e-42	FALSE	TRUE
ENST00000525029	ENSG00000052841	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC17	protein_coding	non_stop_decay	21.61228	10.38088	26.38333	0.442421	0.1515349	1.344856	1.874780	0.3340855	1.051735	0.1724965	0.6351639	1.625585	0.08222500	0.03116667	0.03976667	0.00860000	1.000000e+00	1.849113e-42	FALSE	FALSE
ENST00000525135	ENSG00000052841	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC17	protein_coding	retained_intron	21.61228	10.38088	26.38333	0.442421	0.1515349	1.344856	1.726485	0.6098224	2.000582	0.2996791	0.2086770	1.697687	0.07903333	0.06006667	0.07573333	0.01566667	7.122453e-01	1.849113e-42	FALSE	FALSE
MSTRG.5401.1	ENSG00000052841	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC17	protein_coding		21.61228	10.38088	26.38333	0.442421	0.1515349	1.344856	5.229555	1.6889975	7.559297	0.2184947	1.2380198	2.155476	0.21791250	0.16450000	0.28683333	0.12233333	1.719425e-01	1.849113e-42	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 49
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000052841	E001	0.5806908	0.8400229652	7.690812e-01	8.508086e-01	11	43358642	43358919	278	+	0.233	0.000	-11.513
ENSG00000052841	E002	0.7279398	0.2707950924	3.154114e-01	4.581744e-01	11	43358920	43358931	12	+	0.277	0.000	-11.724
ENSG00000052841	E003	10.2217230	0.0016049193	4.710338e-03	1.512473e-02	11	43358932	43358953	22	+	1.070	0.711	-1.379
ENSG00000052841	E004	45.5500909	0.0185284358	1.927718e-03	7.001407e-03	11	43358954	43359113	160	+	1.673	1.396	-0.946
ENSG00000052841	E005	1.0340911	0.0117189443	5.274925e-01	6.605514e-01	11	43370079	43370385	307	+	0.317	0.201	-0.866
ENSG00000052841	E006	35.1523139	0.0095531173	5.199636e-03	1.647360e-02	11	43379233	43379257	25	+	1.554	1.327	-0.783
ENSG00000052841	E007	50.1444328	0.0046112000	6.318611e-04	2.650317e-03	11	43379258	43379322	65	+	1.706	1.485	-0.752
ENSG00000052841	E008	82.6431567	0.0014494459	2.813291e-05	1.684267e-04	11	43389652	43389821	170	+	1.916	1.724	-0.647
ENSG00000052841	E009	84.7635385	0.0212323912	2.257175e-02	5.686521e-02	11	43391465	43391576	112	+	1.921	1.758	-0.551
ENSG00000052841	E010	0.2987644	0.0273176773	7.734755e-01		11	43391577	43391788	212	+	0.133	0.000	-10.409
ENSG00000052841	E011	91.3956548	0.0003148923	1.346203e-06	1.087426e-05	11	43391821	43391952	132	+	1.961	1.761	-0.672
ENSG00000052841	E012	3.2479372	0.1461496645	8.002258e-01	8.726457e-01	11	43396136	43396708	573	+	0.609	0.525	-0.382
ENSG00000052841	E013	79.8264198	0.0073106197	1.696329e-02	4.485574e-02	11	43396709	43396818	110	+	1.887	1.757	-0.436
ENSG00000052841	E014	1.7391257	0.0080055542	3.706102e-01	5.150220e-01	11	43396997	43397346	350	+	0.353	0.527	0.912
ENSG00000052841	E015	92.1679362	0.0003030089	2.805278e-02	6.811997e-02	11	43397347	43397491	145	+	1.938	1.864	-0.250
ENSG00000052841	E016	70.6780260	0.0009429570	2.632815e-02	6.460464e-02	11	43397974	43398032	59	+	1.827	1.734	-0.315
ENSG00000052841	E017	75.3504585	0.0011507686	1.342514e-03	5.118132e-03	11	43398033	43398113	81	+	1.864	1.720	-0.487
ENSG00000052841	E018	109.9722608	0.0160290393	1.377990e-01	2.450126e-01	11	43399888	43400048	161	+	2.014	1.928	-0.287
ENSG00000052841	E019	88.3910110	0.0003356778	5.572143e-02	1.192164e-01	11	43401446	43401558	113	+	1.914	1.850	-0.217
ENSG00000052841	E020	2.7529515	0.0128900002	6.227288e-04	2.616008e-03	11	43401559	43401622	64	+	0.317	0.874	2.592
ENSG00000052841	E021	66.3493931	0.0003633760	1.669556e-04	8.220940e-04	11	43403998	43404051	54	+	1.818	1.639	-0.606
ENSG00000052841	E022	90.8517750	0.0003006461	3.123815e-04	1.430119e-03	11	43404052	43404144	93	+	1.944	1.804	-0.474
ENSG00000052841	E023	98.9068702	0.0002999762	1.047154e-02	2.991121e-02	11	43405514	43405629	116	+	1.968	1.881	-0.294
ENSG00000052841	E024	1.1909051	0.0107180627	7.202688e-02	1.467045e-01	11	43405630	43405785	156	+	0.386	0.000	-12.409
ENSG00000052841	E025	112.0196207	0.0002952426	3.907570e-02	8.933536e-02	11	43405786	43405951	166	+	2.018	1.958	-0.202
ENSG00000052841	E026	72.9117885	0.0003788049	2.180013e-02	5.525707e-02	11	43407138	43407215	78	+	1.840	1.748	-0.310
ENSG00000052841	E027	134.8881769	0.0002707611	6.963375e-02	1.427494e-01	11	43407353	43407577	225	+	2.093	2.049	-0.147
ENSG00000052841	E028	144.9962372	0.0002284222	7.705560e-02	1.547724e-01	11	43414590	43414776	187	+	2.124	2.085	-0.133
ENSG00000052841	E029	72.1851261	0.0054121933	8.056805e-01	8.764650e-01	11	43436164	43436221	58	+	1.804	1.835	0.105
ENSG00000052841	E030	99.7173835	0.0098154286	9.521612e-01	9.740488e-01	11	43436222	43436334	113	+	1.948	1.960	0.040
ENSG00000052841	E031	185.0081024	0.0039701812	1.908102e-01	3.147639e-01	11	43443325	43443584	260	+	2.198	2.273	0.249
ENSG00000052841	E032	115.0038816	0.0003466861	2.525910e-02	6.240397e-02	11	43444056	43444209	154	+	1.986	2.087	0.338
ENSG00000052841	E033	5.9290384	0.0026873375	7.684171e-03	2.298663e-02	11	43444210	43444505	296	+	0.872	0.443	-1.864
ENSG00000052841	E034	66.5596836	0.0004030114	2.243876e-09	3.115898e-08	11	43445931	43446719	789	+	1.683	1.972	0.975
ENSG00000052841	E035	14.6764471	0.0452338259	9.748784e-01	9.883540e-01	11	43447584	43448001	418	+	1.138	1.151	0.048
ENSG00000052841	E036	83.5358846	0.0003472183	1.419788e-02	3.867299e-02	11	43448002	43448122	121	+	1.841	1.964	0.413
ENSG00000052841	E037	0.6235652	0.0229257294	1.000000e+00	1.000000e+00	11	43448603	43450081	1479	+	0.187	0.202	0.136
ENSG00000052841	E038	69.2271612	0.0037562046	1.347133e-01	2.407008e-01	11	43450082	43450137	56	+	1.767	1.867	0.336
ENSG00000052841	E039	78.8280088	0.0074603225	3.553662e-01	4.997109e-01	11	43450138	43450241	104	+	1.831	1.905	0.250
ENSG00000052841	E040	0.0000000				11	43451180	43451181	2	+
ENSG00000052841	E041	70.0963223	0.0010844871	9.681673e-02	1.856159e-01	11	43451182	43451265	84	+	1.771	1.871	0.334
ENSG00000052841	E042	0.1817044	0.0401240312	1.445046e-01		11	43468156	43468363	208	+	0.000	0.202	12.575
ENSG00000052841	E043	0.6017953	0.1575673617	3.507721e-01	4.949444e-01	11	43486416	43486451	36	+	0.235	0.000	-11.413
ENSG00000052841	E044	4.4338733	0.0043656248	3.222899e-04	1.470010e-03	11	43489797	43490238	442	+	0.473	0.994	2.169
ENSG00000052841	E045	89.0342048	0.0004289087	3.593890e-02	8.346737e-02	11	43490239	43490358	120	+	1.871	1.977	0.357
ENSG00000052841	E046	5.3043312	0.2413525526	2.046424e-01	3.319567e-01	11	43490718	43492019	1302	+	0.628	0.962	1.330
ENSG00000052841	E047	127.9904491	0.0013314961	2.651656e-03	9.228197e-03	11	43492020	43492163	144	+	2.020	2.152	0.442
ENSG00000052841	E048	0.0000000				11	43492164	43492164	1	+
ENSG00000052841	E049	360.1435804	0.0040516224	1.457016e-16	6.147603e-15	11	43493773	43494933	1161	+	2.407	2.700	0.976

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000052841

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3