• ENSG00000034152
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000034152

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000342679 ENSG00000034152 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP2K3 protein_coding protein_coding 51.78494 92.54426 38.2115 3.52967 1.469907 -1.275915 31.194217 43.742187 28.398867 6.1540451 0.3746392 -0.6230138 0.6227583 0.4688333 0.74566667 0.276833333 1.226871e-03 1.105812e-45 FALSE TRUE
ENST00000361818 ENSG00000034152 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP2K3 protein_coding protein_coding 51.78494 92.54426 38.2115 3.52967 1.469907 -1.275915 12.793471 39.216131 0.000000 2.3147290 0.0000000 -11.9375993 0.2017167 0.4270333 0.00000000 -0.427033333 1.105812e-45 1.105812e-45 FALSE TRUE
ENST00000526076 ENSG00000034152 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP2K3 protein_coding protein_coding 51.78494 92.54426 38.2115 3.52967 1.469907 -1.275915 2.372157 0.000000 5.387197 0.0000000 1.2527404 9.0760666 0.0701625 0.0000000 0.13900000 0.139000000 2.049332e-30 1.105812e-45 FALSE FALSE
MSTRG.13911.10 ENSG00000034152 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP2K3 protein_coding   51.78494 92.54426 38.2115 3.52967 1.469907 -1.275915 3.376161 6.458774 2.969214 0.2320963 0.2651087 -1.1185607 0.0627000 0.0700000 0.07743333 0.007433333 7.167533e-01 1.105812e-45 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000034152 E001 0.2903454 0.3139684026 7.350700e-02   17 21284672 21284709 38 + 0.313 0.000 -12.151
ENSG00000034152 E002 0.2903454 0.3139684026 7.350700e-02   17 21284710 21284710 1 + 0.313 0.000 -13.946
ENSG00000034152 E003 0.6235652 0.0196347489 4.529050e-02 1.007237e-01 17 21284711 21284717 7 + 0.414 0.079 -2.995
ENSG00000034152 E004 83.7619101 0.0580894387 2.742153e-04 1.274860e-03 17 21284718 21284821 104 + 2.123 1.724 -1.340
ENSG00000034152 E005 231.5891195 0.0013911769 3.564501e-12 7.986801e-11 17 21284822 21284969 148 + 2.428 2.241 -0.624
ENSG00000034152 E006 0.0000000       17 21287991 21288035 45 +      
ENSG00000034152 E007 0.0000000       17 21288036 21288045 10 +      
ENSG00000034152 E008 0.0000000       17 21288046 21288091 46 +      
ENSG00000034152 E009 0.4407149 0.0229052002 1.482350e-01 2.592806e-01 17 21291437 21291468 32 + 0.314 0.079 -2.412
ENSG00000034152 E010 0.4417591 0.0972799503 7.720487e-01 8.528840e-01 17 21291469 21291547 79 + 0.185 0.145 -0.425
ENSG00000034152 E011 0.5932745 0.0205900978 3.181011e-01 4.610458e-01 17 21291548 21291717 170 + 0.314 0.146 -1.414
ENSG00000034152 E012 0.7436440 0.2053587091 5.015240e-01 6.376744e-01 17 21295675 21295769 95 + 0.314 0.199 -0.871
ENSG00000034152 E013 1.4822776 0.0143652077 5.000887e-01 6.363577e-01 17 21296086 21296151 66 + 0.414 0.301 -0.669
ENSG00000034152 E014 1.9240246 0.0102412893 5.259111e-02 1.137731e-01 17 21296152 21296210 59 + 0.622 0.301 -1.670
ENSG00000034152 E015 242.9229485 0.0002061489 1.355355e-06 1.094166e-05 17 21298413 21298479 67 + 2.389 2.288 -0.338
ENSG00000034152 E016 252.8896161 0.0014582189 6.949072e-05 3.775397e-04 17 21298878 21298926 49 + 2.403 2.306 -0.325
ENSG00000034152 E017 2.0606776 0.1556428598 8.089741e-02 1.609394e-01 17 21300471 21300544 74 + 0.673 0.307 -1.851
ENSG00000034152 E018 445.6603444 0.0001467696 5.102064e-04 2.197900e-03 17 21300545 21300658 114 + 2.611 2.566 -0.148
ENSG00000034152 E019 553.8394806 0.0003516646 1.646329e-05 1.041063e-04 17 21300874 21300993 120 + 2.714 2.658 -0.188
ENSG00000034152 E020 580.1969126 0.0015608130 2.699144e-02 6.597827e-02 17 21302143 21302259 117 + 2.715 2.685 -0.099
ENSG00000034152 E021 424.9923704 0.0010735365 7.712221e-01 8.522961e-01 17 21303183 21303234 52 + 2.546 2.561 0.052
ENSG00000034152 E022 573.1171257 0.0001698359 8.080738e-01 8.780412e-01 17 21304426 21304553 128 + 2.674 2.691 0.059
ENSG00000034152 E023 515.4957001 0.0001311398 8.652990e-01 9.172148e-01 17 21305051 21305128 78 + 2.627 2.646 0.062
ENSG00000034152 E024 18.2428170 0.0055903594 2.843096e-01 4.245398e-01 17 21311687 21312141 455 + 1.121 1.249 0.455
ENSG00000034152 E025 638.2597992 0.0002943323 2.287070e-03 8.111098e-03 17 21312142 21312281 140 + 2.675 2.751 0.253
ENSG00000034152 E026 435.9299077 0.0003015882 5.614996e-02 1.199693e-01 17 21313492 21313537 46 + 2.521 2.582 0.206
ENSG00000034152 E027 6.4658175 0.0026519797 7.086382e-01 8.062523e-01 17 21313538 21313886 349 + 0.762 0.832 0.277
ENSG00000034152 E028 1995.8473443 0.0023323887 1.765819e-10 2.987133e-09 17 21314147 21315232 1086 + 3.111 3.261 0.499