ENSG00000147162

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373701 ENSG00000147162 HEK293_DMSO_6hB HEK293_TMG_6hB OGT protein_coding protein_coding 30.39283 50.96867 36.08302 3.217625 2.108495 -0.4981739 1.045033 1.040661 0.000000 1.0406611 0.0000000 -6.71515358 0.05921667 0.02336667 0.0000000 -0.02336667 9.762437e-01 3.571236e-35 FALSE TRUE
ENST00000373719 ENSG00000147162 HEK293_DMSO_6hB HEK293_TMG_6hB OGT protein_coding protein_coding 30.39283 50.96867 36.08302 3.217625 2.108495 -0.4981739 15.114987 33.326187 9.303526 1.7400116 0.5263989 -1.83968977 0.53154583 0.65496667 0.2581333 -0.39683333 3.571236e-35 3.571236e-35 FALSE TRUE
ENST00000459760 ENSG00000147162 HEK293_DMSO_6hB HEK293_TMG_6hB OGT protein_coding processed_transcript 30.39283 50.96867 36.08302 3.217625 2.108495 -0.4981739 2.540424 3.381360 3.351687 1.6942209 1.2446379 -0.01267853 0.06507917 0.06236667 0.0897000 0.02733333 9.505325e-01 3.571236e-35 FALSE FALSE
MSTRG.34438.1 ENSG00000147162 HEK293_DMSO_6hB HEK293_TMG_6hB OGT protein_coding   30.39283 50.96867 36.08302 3.217625 2.108495 -0.4981739 1.759288 1.901893 2.595788 0.4774995 0.3169475 0.44671754 0.05898750 0.03886667 0.0732000 0.03433333 7.949447e-01 3.571236e-35 FALSE TRUE
MSTRG.34438.4 ENSG00000147162 HEK293_DMSO_6hB HEK293_TMG_6hB OGT protein_coding   30.39283 50.96867 36.08302 3.217625 2.108495 -0.4981739 5.426363 6.829012 14.095421 0.9450096 0.5128766 1.04438977 0.14157917 0.13270000 0.3921000 0.25940000 5.113612e-13 3.571236e-35 FALSE TRUE
MSTRG.34438.5 ENSG00000147162 HEK293_DMSO_6hB HEK293_TMG_6hB OGT protein_coding   30.39283 50.96867 36.08302 3.217625 2.108495 -0.4981739 2.497522 1.889300 4.402638 0.6633229 0.7510652 1.21617359 0.08895000 0.03843333 0.1223000 0.08386667 7.053845e-01 3.571236e-35 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_6hB HEK293_DMSO_6hB log2fold_HEK293_DMSO_6hB_HEK293_TMG_6hB
ENSG00000147162 E001 9.6915227 2.229768e-02 3.390446e-01 9.404130e-01 X 71533096 71533103 8 + 0.973 1.070 0.357
ENSG00000147162 E002 10.9946034 1.599445e-02 2.108602e-01 9.404130e-01 X 71533104 71533110 7 + 1.007 1.129 0.443
ENSG00000147162 E003 54.6638822 6.814690e-04 1.945273e-01 9.404130e-01 X 71533111 71533122 12 + 1.719 1.759 0.136
ENSG00000147162 E004 59.7873332 6.467846e-04 1.603386e-01 9.404130e-01 X 71533123 71533127 5 + 1.755 1.798 0.144
ENSG00000147162 E005 240.6864343 4.313990e-04 2.886603e-04 2.829822e-01 X 71533128 71533299 172 + 2.341 2.407 0.221
ENSG00000147162 E006 183.2868181 1.098721e-03 4.676455e-02 9.404130e-01 X 71533300 71533336 37 + 2.240 2.277 0.122
ENSG00000147162 E007 0.5175512 2.174769e-02 7.180071e-01   X 71534301 71534373 73 + 0.141 0.195 0.564
ENSG00000147162 E008 159.1472679 3.514761e-04 2.807687e-01 9.404130e-01 X 71536178 71536207 30 + 2.195 2.203 0.026
ENSG00000147162 E009 288.3032730 2.165429e-04 4.194540e-03 6.410252e-01 X 71536208 71536358 151 + 2.433 2.472 0.130
ENSG00000147162 E010 0.9716516 1.537876e-02 7.676316e-01   X 71536359 71536657 299 + 0.332 0.267 -0.434
ENSG00000147162 E011 0.8068277 1.621511e-02 8.627643e-01   X 71537014 71537110 97 + 0.247 0.267 0.150
ENSG00000147162 E012 348.7947194 1.441998e-04 7.846036e-06 3.857532e-02 X 71537829 71538072 244 + 2.501 2.566 0.214
ENSG00000147162 E013 181.0501744 2.499495e-04 1.306014e-08 2.518636e-04 X 71544567 71544635 69 + 2.175 2.309 0.447
ENSG00000147162 E014 640.0015799 6.463660e-03 8.856274e-18 3.820109e-13 X 71544636 71546210 1575 + 2.972 2.604 -1.226
ENSG00000147162 E015 93.4550449 1.226702e-02 1.889369e-09 4.656970e-05 X 71546211 71546280 70 + 2.156 1.741 -1.397
ENSG00000147162 E016 79.4729980 1.815477e-02 1.313782e-08 2.518636e-04 X 71546281 71546343 63 + 2.101 1.638 -1.560
ENSG00000147162 E017 148.1470153 6.835291e-03 2.632571e-17 9.084370e-13 X 71546344 71546489 146 + 2.366 1.914 -1.512
ENSG00000147162 E018 654.8343787 1.495891e-04 9.967072e-134 1.719699e-128 X 71546490 71547906 1417 + 2.988 2.598 -1.296
ENSG00000147162 E019 296.3742475 1.639957e-04 4.220246e-04 3.329546e-01 X 71547907 71548023 117 + 2.438 2.490 0.172
ENSG00000147162 E020 0.5235010 2.659300e-02 5.317648e-02   X 71553621 71553645 25 + 0.333 0.000 -10.596
ENSG00000147162 E021 263.4606089 2.543341e-03 5.566308e-01 9.411945e-01 X 71554513 71554592 80 + 2.419 2.415 -0.014
ENSG00000147162 E022 367.1255258 1.408829e-04 1.127338e-06 1.023729e-02 X 71555190 71555385 196 + 2.520 2.590 0.233
ENSG00000147162 E023 1.1552491 1.369686e-02 4.879225e-01 9.404130e-01 X 71555813 71555953 141 + 0.403 0.267 -0.849
ENSG00000147162 E024 331.6635309 1.890310e-04 1.428383e-02 8.207105e-01 X 71555954 71556094 141 + 2.502 2.528 0.087
ENSG00000147162 E025 0.7042412 6.396525e-02 8.164978e-01   X 71556456 71556679 224 + 0.248 0.195 -0.440
ENSG00000147162 E026 252.6437329 2.185092e-04 6.070770e-03 7.052613e-01 X 71556680 71556780 101 + 2.375 2.415 0.134
ENSG00000147162 E027 294.6877188 2.238317e-04 2.416822e-01 9.404130e-01 X 71556952 71557105 154 + 2.464 2.466 0.004
ENSG00000147162 E028 255.2153955 3.689342e-04 5.345622e-02 9.404130e-01 X 71557195 71557296 102 + 2.390 2.412 0.073
ENSG00000147162 E029 334.1678544 2.033014e-04 8.108063e-04 4.239239e-01 X 71557493 71557672 180 + 2.495 2.539 0.148
ENSG00000147162 E030 365.9603057 1.485718e-04 6.280533e-05 1.197180e-01 X 71559267 71559425 159 + 2.529 2.582 0.177
ENSG00000147162 E031 284.5164699 1.945128e-04 1.627160e-03 5.103705e-01 X 71559588 71559677 90 + 2.424 2.469 0.151
ENSG00000147162 E032 261.8595818 1.817920e-04 1.085129e-01 9.404130e-01 X 71561775 71561900 126 + 2.407 2.420 0.041
ENSG00000147162 E033 351.0723532 1.814882e-04 2.502414e-02 8.866532e-01 X 71562847 71563017 171 + 2.530 2.551 0.068
ENSG00000147162 E034 364.7445100 1.638580e-04 2.971401e-02 9.067556e-01 X 71563130 71563246 117 + 2.547 2.565 0.060
ENSG00000147162 E035 454.0003866 1.061437e-03 2.971694e-01 9.404130e-01 X 71563329 71563499 171 + 2.654 2.652 -0.005
ENSG00000147162 E036 282.0788789 8.564970e-04 3.161485e-01 9.404130e-01 X 71564601 71564663 63 + 2.446 2.447 0.004
ENSG00000147162 E037 313.8702379 2.059060e-04 3.237643e-02 9.175030e-01 X 71564664 71564753 90 + 2.481 2.502 0.070
ENSG00000147162 E038 474.8981354 3.555298e-04 6.806498e-05 1.223312e-01 X 71567500 71567752 253 + 2.645 2.694 0.163
ENSG00000147162 E039 3.3211021 5.901305e-03 5.895064e-01 9.429376e-01 X 71567753 71567973 221 + 0.684 0.584 -0.436
ENSG00000147162 E040 364.1037660 1.680732e-04 1.004926e-03 4.461806e-01 X 71567993 71568116 124 + 2.535 2.575 0.133
ENSG00000147162 E041 1906.8220255 5.687256e-05 2.847852e-22 2.456814e-17 X 71573620 71575892 2273 + 3.244 3.298 0.181