• ENSG00000046653
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000046653

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000316715 ENSG00000046653 HEK293_DMSO_2hB HEK293_TMG_2hB GPM6B protein_coding protein_coding 7.282562 13.98717 12.21112 0.5678724 0.09077589 -0.1957594 0.4822737 0.8210568 0.7466391 0.1896032 0.1455658 -0.13534182 0.10801250 0.05906667 0.06110000 0.002033333 1.000000e+00 3.988499e-15 FALSE TRUE
ENST00000454189 ENSG00000046653 HEK293_DMSO_2hB HEK293_TMG_2hB GPM6B protein_coding protein_coding 7.282562 13.98717 12.21112 0.5678724 0.09077589 -0.1957594 4.1272313 7.1681183 7.3981015 0.1950056 0.5575216 0.04549817 0.58579583 0.51310000 0.60643333 0.093333333 8.535197e-01 3.988499e-15 FALSE TRUE
ENST00000472735 ENSG00000046653 HEK293_DMSO_2hB HEK293_TMG_2hB GPM6B protein_coding processed_transcript 7.282562 13.98717 12.21112 0.5678724 0.09077589 -0.1957594 0.1836437 0.0000000 1.1535607 0.0000000 0.5768802 6.86240272 0.01602917 0.00000000 0.09376667 0.093766667 6.142558e-01 3.988499e-15 FALSE TRUE
MSTRG.33919.2 ENSG00000046653 HEK293_DMSO_2hB HEK293_TMG_2hB GPM6B protein_coding   7.282562 13.98717 12.21112 0.5678724 0.09077589 -0.1957594 0.8678690 1.1840688 1.5696773 0.1629765 0.3355536 0.40374390 0.13124583 0.08553333 0.12826667 0.042733333 9.311750e-01 3.988499e-15 TRUE TRUE
MSTRG.33919.4 ENSG00000046653 HEK293_DMSO_2hB HEK293_TMG_2hB GPM6B protein_coding   7.282562 13.98717 12.21112 0.5678724 0.09077589 -0.1957594 0.7866584 2.5560358 0.7687779 0.3090443 0.4165767 -1.72025739 0.06355833 0.18170000 0.06290000 -0.118800000 9.311750e-01 3.988499e-15 FALSE TRUE
MSTRG.33919.7 ENSG00000046653 HEK293_DMSO_2hB HEK293_TMG_2hB GPM6B protein_coding   7.282562 13.98717 12.21112 0.5678724 0.09077589 -0.1957594 0.3883413 1.5805003 0.0000000 0.2814546 0.0000000 -7.31333680 0.03709583 0.11230000 0.00000000 -0.112300000 3.988499e-15 3.988499e-15 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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©2015-2025 Max Guglielmi
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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_DMSO_2hBColumn filter
log2fold_HEK293_DMSO_2hB_HEK293_TMG_2hBColumn filter
ENSG00000046653 E001 7.0819496 0.0040317273 0.5321422618   X 13770939 13771100 162 - 0.947 0.872 -0.285
ENSG00000046653 E002 39.8285885 0.0181006294 0.2897260422 0.93343795 X 13771101 13771455 355 - 1.655 1.567 -0.301
ENSG00000046653 E003 138.6040197 0.0002738559 0.0001987501 0.05594485 X 13771456 13772100 645 - 2.201 2.089 -0.373
ENSG00000046653 E004 175.5854297 0.0001200704 0.1959324008 0.89200622 X 13772101 13772698 598 - 2.264 2.230 -0.114
ENSG00000046653 E005 89.9671128 0.0002132108 0.9854312838 0.99903573 X 13772699 13772853 155 - 1.959 1.957 -0.005
ENSG00000046653 E006 108.4014178 0.0008606251 0.5925169563 0.97674057 X 13772854 13773030 177 - 2.049 2.029 -0.067
ENSG00000046653 E007 193.3362159 0.0014107140 0.0925860298 0.79124731 X 13773031 13773864 834 - 2.315 2.264 -0.171
ENSG00000046653 E008 59.4566689 0.0061779389 0.1733101316 0.87674103 X 13773865 13773953 89 - 1.823 1.742 -0.275
ENSG00000046653 E009 123.2685643 0.0004670822 0.5379463592 0.97255154 X 13773954 13774308 355 - 2.085 2.104 0.064
ENSG00000046653 E010 52.3130205 0.0003495325 0.1729184562 0.87627065 X 13774309 13774336 28 - 1.692 1.757 0.221
ENSG00000046653 E011 80.7534895 0.0015349887 0.9993065883 0.99995869 X 13774337 13774466 130 - 1.912 1.911 -0.004
ENSG00000046653 E012 109.8611732 0.0033500217 0.4054468842 0.95718333 X 13774467 13774624 158 - 2.063 2.025 -0.127
ENSG00000046653 E013 0.8352301 0.1130556323 0.7891600055   X 13776167 13776237 71 - 0.234 0.284 0.365
ENSG00000046653 E014 112.9050222 0.0001889489 0.7159501152 0.98679464 X 13776238 13776303 66 - 2.049 2.060 0.037
ENSG00000046653 E015 106.7488898 0.0001885094 0.1757065933 0.87836299 X 13777352 13777425 74 - 2.007 2.052 0.151
ENSG00000046653 E016 83.9374168 0.0002687637 0.4177841141 0.95869370 X 13779818 13779852 35 - 1.912 1.942 0.102
ENSG00000046653 E017 94.0339779 0.0002230419 0.8067179942 0.99111030 X 13779853 13779907 55 - 1.972 1.980 0.027
ENSG00000046653 E018 90.0812193 0.0025439628 0.1751409092 0.87779111 X 13779908 13779989 82 - 1.927 1.985 0.194
ENSG00000046653 E019 0.4811529 0.0228761337 0.4841971063   X 13780915 13781005 91 - 0.234 0.116 -1.218
ENSG00000046653 E020 95.2125699 0.0002253266 0.0104839563 0.41908444 X 13783365 13783448 84 - 1.932 2.024 0.307
ENSG00000046653 E021 90.1795937 0.0021308778 0.2105922934 0.90063072 X 13783449 13783521 73 - 1.932 1.986 0.180
ENSG00000046653 E022 0.0000000       X 13783779 13783921 143 -      
ENSG00000046653 E023 130.9500842 0.0057752135 0.3698537010 0.95226864 X 13785622 13785808 187 - 2.098 2.140 0.140
ENSG00000046653 E024 4.3082416 0.0044888551 0.4270604873   X 13807650 13807769 120 - 0.660 0.772 0.461
ENSG00000046653 E025 0.0000000       X 13812871 13812908 38 -      
ENSG00000046653 E026 0.0000000       X 13816844 13817195 352 -      
ENSG00000046653 E027 0.0000000       X 13817196 13817257 62 -      
ENSG00000046653 E028 0.0000000       X 13817258 13817346 89 -      
ENSG00000046653 E029 0.0000000       X 13888981 13889057 77 -      
ENSG00000046653 E030 0.1743023 0.0414608575 0.5547556030   X 13889452 13889612 161 - 0.000 0.116 9.190
ENSG00000046653 E031 0.6162122 0.3452488058 0.8907058845   X 13938327 13938506 180 - 0.233 0.204 -0.239
ENSG00000046653 E032 72.3060896 0.0010257189 0.0924379537 0.79101351 X 13938507 13938797 291 - 1.826 1.899 0.244