ENSG00000244879

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000499624 ENSG00000244879 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 4.539833 6.882916 3.697827 1.366382 0.5779598 -0.8945405 0.9164373 1.3673712 0.5284722 0.43244327 0.27155143 -1.3549735 0.19621250 0.19516667 0.13023333 -0.06493333 0.7404031273 0.0002724453 FALSE FALSE
ENST00000558593 ENSG00000244879 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 4.539833 6.882916 3.697827 1.366382 0.5779598 -0.8945405 0.2633281 0.9414182 0.3415898 0.08327734 0.02656277 -1.4361863 0.05505000 0.14256667 0.09536667 -0.04720000 0.6801191154 0.0002724453   FALSE
ENST00000560359 ENSG00000244879 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 4.539833 6.882916 3.697827 1.366382 0.5779598 -0.8945405 0.3433037 0.5994962 0.0000000 0.14845096 0.00000000 -5.9295454 0.07001667 0.08593333 0.00000000 -0.08593333 0.0002724453 0.0002724453   FALSE
ENST00000619314 ENSG00000244879 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 4.539833 6.882916 3.697827 1.366382 0.5779598 -0.8945405 0.8984801 1.3510613 0.6954551 0.21951376 0.69545507 -0.9481059 0.19248333 0.19880000 0.14813333 -0.05066667 0.4686255456 0.0002724453   FALSE
ENST00000687003 ENSG00000244879 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 4.539833 6.882916 3.697827 1.366382 0.5779598 -0.8945405 0.6264689 0.0000000 1.2996567 0.00000000 0.67583937 7.0330449 0.17460417 0.00000000 0.40580000 0.40580000 0.1899903922 0.0002724453 FALSE FALSE
ENST00000689965 ENSG00000244879 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 4.539833 6.882916 3.697827 1.366382 0.5779598 -0.8945405 0.5715878 0.9038578 0.0000000 0.48456827 0.00000000 -6.5138978 0.11992917 0.16083333 0.00000000 -0.16083333 0.3195660442 0.0002724453   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000244879 E001 2.985527 0.0091024854 0.0500655383 0.34427103 15 50354950 50354958 9 + 0.733 0.478 -1.138
ENSG00000244879 E002 3.521443 0.0615240275 0.1286587285 0.50814685 15 50354959 50354964 6 + 0.765 0.546 -0.941
ENSG00000244879 E003 3.810730 0.0579928135 0.0615168558 0.37564567 15 50354965 50354970 6 + 0.821 0.546 -1.161
ENSG00000244879 E004 21.765511 0.0321991148 0.0221899852 0.24649364 15 50354971 50355248 278 + 1.450 1.257 -0.674
ENSG00000244879 E005 13.264392 0.0199965838 0.0172469682 0.22197886 15 50355249 50355327 79 + 1.260 1.052 -0.742
ENSG00000244879 E006 17.835093 0.0389725574 0.0040632092 0.11406240 15 50355328 50355459 132 + 1.416 1.139 -0.974
ENSG00000244879 E007 7.317314 0.0247513438 0.0030054788 0.09870156 15 50355460 50355465 6 + 1.087 0.760 -1.237
ENSG00000244879 E008 6.577037 0.0071837711 0.0019987346 0.07961738 15 50355466 50355466 1 + 1.042 0.721 -1.236
ENSG00000244879 E009 6.464521 0.0049622375 0.0029837160 0.09825688 15 50355467 50355467 1 + 1.027 0.721 -1.178
ENSG00000244879 E010 7.670292 0.0309539720 0.0038483312 0.11100901 15 50355468 50355475 8 + 1.101 0.779 -1.216
ENSG00000244879 E011 10.238345 0.0430562421 0.0034728234 0.10605194 15 50355476 50355492 17 + 1.212 0.889 -1.181
ENSG00000244879 E012 21.837547 0.0270021525 0.0012806418 0.06245258 15 50355493 50355544 52 + 1.494 1.224 -0.936
ENSG00000244879 E013 18.236595 0.0267289930 0.0072245337 0.14963208 15 50355545 50355545 1 + 1.399 1.170 -0.806
ENSG00000244879 E014 14.579723 0.0024031049 0.0005490862 0.03818234 15 50355546 50355552 7 + 1.315 1.071 -0.869
ENSG00000244879 E015 44.321604 0.0175539480 0.0607127143 0.37334928 15 50355553 50355765 213 + 1.696 1.607 -0.303
ENSG00000244879 E016 12.995211 0.0047630178 0.1126916713 0.48036199 15 50355766 50355783 18 + 1.189 1.089 -0.358
ENSG00000244879 E017 10.046716 0.0028294769 0.2210753776 0.62568217 15 50355784 50355788 5 + 1.073 1.001 -0.264
ENSG00000244879 E018 22.482454 0.0179585441 0.1244926023 0.50138643 15 50355789 50355932 144 + 1.406 1.322 -0.290
ENSG00000244879 E019 19.164516 0.0946635066 0.2712813009 0.67538692 15 50355933 50356099 167 + 1.351 1.253 -0.340
ENSG00000244879 E020 30.814031 0.1254071019 0.5993760365 0.87528495 15 50356100 50356257 158 + 1.494 1.483 -0.035
ENSG00000244879 E021 10.372256 0.0749806769 0.5349245646 0.84742469 15 50356258 50356307 50 + 1.051 1.023 -0.103
ENSG00000244879 E022 12.647522 0.0023054159 0.1995586521 0.60282676 15 50356308 50356470 163 + 0.992 1.177 0.667
ENSG00000244879 E023 33.924863 0.0074807589 0.0375330405 0.30571263 15 50356471 50356918 448 + 1.382 1.584 0.696
ENSG00000244879 E024 105.376751 0.0999471448 0.0837802849 0.42533101 15 50356919 50360328 3410 + 1.901 2.057 0.525
ENSG00000244879 E025 60.282528 0.0779317022 0.1183045673 0.49063072 15 50360329 50361963 1635 + 1.662 1.816 0.520
ENSG00000244879 E026 11.646380 0.0174817750 0.4990716627 0.82907665 15 50361964 50362081 118 + 0.993 1.136 0.522
ENSG00000244879 E027 153.154786 0.0501864936 0.0639619738 0.38148560 15 50362082 50367380 5299 + 2.055 2.221 0.553
ENSG00000244879 E028 149.914662 0.0084002064 0.0007002219 0.04440607 15 50367381 50370329 2949 + 2.018 2.219 0.672
ENSG00000244879 E029 5.617607 0.0041590731 0.8035594034 0.94939913 15 50370330 50370331 2 + 0.794 0.813 0.078
ENSG00000244879 E030 84.360429 0.0004072238 0.0069565830 0.14711185 15 50370332 50372202 1871 + 1.798 1.965 0.563