ENSG00000232098

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000593393 ENSG00000232098 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 10.68216 11.49561 17.11032 1.118516 1.617907 0.5733722 4.9658648 5.2269762 8.5886299 0.1152676 0.85639362 0.7153728 0.45054583 0.46260000 0.50143333 0.03883333 0.75353540 0.04919408 FALSE  
ENST00000597980 ENSG00000232098 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA lncRNA 10.68216 11.49561 17.11032 1.118516 1.617907 0.5733722 2.2050353 2.2410907 3.4535145 0.6533937 0.22213474 0.6216125 0.20296250 0.18873333 0.20490000 0.01616667 0.88158444 0.04919408    
MSTRG.17850.2 ENSG00000232098 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA   10.68216 11.49561 17.11032 1.118516 1.617907 0.5733722 0.6690877 0.6059621 1.4108172 0.3589509 0.25433467 1.2058074 0.06028333 0.04900000 0.08473333 0.03573333 0.73928378 0.04919408 FALSE  
MSTRG.17850.4 ENSG00000232098 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA   10.68216 11.49561 17.11032 1.118516 1.617907 0.5733722 0.9899062 1.6035931 1.1290081 0.1126330 0.06645517 -0.5024988 0.09290417 0.14026667 0.06680000 -0.07346667 0.04919408 0.04919408 FALSE  
MSTRG.17850.5 ENSG00000232098 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA   10.68216 11.49561 17.11032 1.118516 1.617907 0.5733722 0.6837396 0.5759733 1.1670586 0.2880986 0.47335912 1.0062793 0.07804167 0.05550000 0.06490000 0.00940000 0.85285141 0.04919408 FALSE  
MSTRG.17850.6 ENSG00000232098 HEK293_DMSO_6hA HEK293_OSMI2_6hA   lncRNA   10.68216 11.49561 17.11032 1.118516 1.617907 0.5733722 0.6871459 0.8427058 0.7674686 0.1824300 0.11220215 -0.1332635 0.06916667 0.07296667 0.04470000 -0.02826667 0.64043324 0.04919408 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000232098 E001 17.54924 0.0153344863 0.606736332 0.87834963 19 58404235 58404237 3 - 1.301 1.245 -0.197
ENSG00000232098 E002 46.94972 0.0006678167 0.575459182 0.86459800 19 58404238 58404311 74 - 1.693 1.663 -0.101
ENSG00000232098 E003 40.54809 0.0006550940 0.838722591 0.95978041 19 58404312 58404391 80 - 1.621 1.609 -0.041
ENSG00000232098 E004 22.90283 0.0023607086 0.886174835 0.97277786 19 58404392 58404409 18 - 1.373 1.381 0.028
ENSG00000232098 E005 19.67492 0.0167450096 0.820294287 0.95459165 19 58404410 58404429 20 - 1.326 1.295 -0.108
ENSG00000232098 E006 26.10978 0.0012633099 0.275262281 0.67898282 19 58404430 58404542 113 - 1.469 1.394 -0.259
ENSG00000232098 E007 79.29638 0.0010456854 0.255276912 0.66105674 19 58404543 58404719 177 - 1.926 1.878 -0.161
ENSG00000232098 E008 82.01819 0.0004322070 0.048142652 0.33922995 19 58404720 58404825 106 - 1.952 1.874 -0.261
ENSG00000232098 E009 29.48716 0.0020773100 0.001824251 0.07599024 19 58404826 58404830 5 - 1.565 1.354 -0.726
ENSG00000232098 E010 72.22250 0.0003938524 0.001797060 0.07537239 19 58404831 58405006 176 - 1.916 1.786 -0.439
ENSG00000232098 E011 43.62575 0.0007866238 0.013945536 0.20256845 19 58405007 58405137 131 - 1.705 1.572 -0.449
ENSG00000232098 E012 29.21935 0.0060399285 0.013709636 0.20133105 19 58405138 58405231 94 - 1.554 1.375 -0.615
ENSG00000232098 E013 54.94229 0.0067841869 0.023969776 0.25419222 19 58405232 58405407 176 - 1.805 1.671 -0.455
ENSG00000232098 E014 257.54571 0.0042533078 0.651060057 0.89698372 19 58405408 58406395 988 - 2.419 2.404 -0.049
ENSG00000232098 E015 84.57219 0.0075048808 0.691638731 0.91233235 19 58406396 58406558 163 - 1.917 1.936 0.063
ENSG00000232098 E016 166.97140 0.0018172251 0.207380293 0.61129292 19 58406559 58406770 212 - 2.201 2.240 0.131
ENSG00000232098 E017 205.07304 0.0006757852 0.189012925 0.59038651 19 58406771 58407129 359 - 2.292 2.325 0.113
ENSG00000232098 E018 129.26865 0.0007169794 0.054303099 0.35670164 19 58407130 58407320 191 - 2.080 2.141 0.203
ENSG00000232098 E019 115.74401 0.0003333513 0.103837249 0.46430737 19 58407414 58407576 163 - 2.042 2.093 0.170
ENSG00000232098 E020 104.16453 0.0003377243 0.001090236 0.05684768 19 58407902 58408058 157 - 1.964 2.073 0.368
ENSG00000232098 E021 58.50983 0.0005124267 0.006688513 0.14422209 19 58408059 58408126 68 - 1.707 1.830 0.415
ENSG00000232098 E022 29.59207 0.0043293579 0.046911580 0.33573227 19 58408127 58408144 18 - 1.413 1.551 0.476
ENSG00000232098 E023 79.93124 0.0055953779 0.478958375 0.81865428 19 58408145 58408347 203 - 1.885 1.926 0.140
ENSG00000232098 E024 33.25690 0.0007921524 0.871314176 0.96851055 19 58408348 58408365 18 - 1.534 1.524 -0.036
ENSG00000232098 E025 39.99648 0.0007942491 0.331758994 0.72591144 19 58408366 58408484 119 - 1.635 1.581 -0.184