ENSG00000231584

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000467292 ENSG00000231584 HEK293_DMSO_6hA HEK293_OSMI2_6hA   transcribed_unprocessed_pseudogene processed_transcript 16.04071 17.99259 23.39111 1.389409 2.16195 0.3783725 2.8111542 3.2594915 4.685608 0.7923796 0.7440963 0.5222457 0.16623750 0.17850000 0.19843333 0.01993333 8.147655e-01 2.317134e-09   FALSE
ENST00000686031 ENSG00000231584 HEK293_DMSO_6hA HEK293_OSMI2_6hA   transcribed_unprocessed_pseudogene processed_transcript 16.04071 17.99259 23.39111 1.389409 2.16195 0.3783725 1.1609457 0.0000000 1.840991 0.0000000 0.6166370 7.5321542 0.06761667 0.00000000 0.07666667 0.07666667 2.317134e-09 2.317134e-09   FALSE
ENST00000686623 ENSG00000231584 HEK293_DMSO_6hA HEK293_OSMI2_6hA   transcribed_unprocessed_pseudogene processed_transcript 16.04071 17.99259 23.39111 1.389409 2.16195 0.3783725 0.8771577 0.6891389 1.198669 0.2125930 0.6129969 0.7897682 0.05221250 0.03690000 0.04770000 0.01080000 9.687817e-01 2.317134e-09   FALSE
ENST00000687200 ENSG00000231584 HEK293_DMSO_6hA HEK293_OSMI2_6hA   transcribed_unprocessed_pseudogene processed_transcript 16.04071 17.99259 23.39111 1.389409 2.16195 0.3783725 0.8727930 0.5015795 1.204484 0.5015795 0.8057250 1.2473127 0.05248750 0.02503333 0.04913333 0.02410000 7.103764e-01 2.317134e-09 FALSE TRUE
ENST00000689315 ENSG00000231584 HEK293_DMSO_6hA HEK293_OSMI2_6hA   transcribed_unprocessed_pseudogene processed_transcript 16.04071 17.99259 23.39111 1.389409 2.16195 0.3783725 1.3814391 2.5998707 2.905654 0.3530975 0.2683453 0.1598412 0.08370000 0.14393333 0.12660000 -0.01733333 7.789671e-01 2.317134e-09   FALSE
ENST00000690531 ENSG00000231584 HEK293_DMSO_6hA HEK293_OSMI2_6hA   transcribed_unprocessed_pseudogene processed_transcript 16.04071 17.99259 23.39111 1.389409 2.16195 0.3783725 1.1526469 2.9082151 1.471024 0.1381587 0.7730587 -0.9784912 0.07796250 0.16493333 0.06726667 -0.09766667 6.452819e-01 2.317134e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000231584 E001 0.0000000       2 96010526 96010531 6 +      
ENSG00000231584 E002 0.0000000       2 96010532 96010534 3 +      
ENSG00000231584 E003 0.1812101 0.0374840826 0.514700665   2 96010535 96010542 8 + 0.116 0.000 -8.524
ENSG00000231584 E004 0.3529782 0.0289857983 0.966181907   2 96010543 96010544 2 + 0.116 0.123 0.096
ENSG00000231584 E005 0.5074389 0.0218998763 0.532682759   2 96010545 96010547 3 + 0.116 0.219 1.096
ENSG00000231584 E006 0.6886490 0.1772697162 0.954475797   2 96010548 96010550 3 + 0.211 0.219 0.060
ENSG00000231584 E007 0.6886490 0.1772697162 0.954475797   2 96010551 96010552 2 + 0.211 0.219 0.060
ENSG00000231584 E008 0.6886490 0.1772697162 0.954475797   2 96010553 96010553 1 + 0.211 0.219 0.060
ENSG00000231584 E009 0.6886490 0.1772697162 0.954475797   2 96010554 96010556 3 + 0.211 0.219 0.060
ENSG00000231584 E010 0.6886490 0.1772697162 0.954475797   2 96010557 96010557 1 + 0.211 0.219 0.060
ENSG00000231584 E011 1.2010903 0.2391467740 0.822685916   2 96010558 96010562 5 + 0.360 0.296 -0.406
ENSG00000231584 E012 1.3136069 0.0607417044 0.559726593   2 96010563 96010563 1 + 0.406 0.297 -0.658
ENSG00000231584 E013 5.8405106 0.0038553409 0.054100040 0.35616730 2 96010564 96010592 29 + 0.938 0.693 -0.960
ENSG00000231584 E014 6.1745441 0.0035989644 0.123479441 0.49967468 2 96010593 96010595 3 + 0.938 0.748 -0.738
ENSG00000231584 E015 8.0093892 0.0030049452 0.467299090 0.81258896 2 96010596 96010601 6 + 0.995 0.915 -0.299
ENSG00000231584 E016 13.3500237 0.0019429698 0.063713118 0.38101180 2 96010602 96010612 11 + 1.229 1.061 -0.602
ENSG00000231584 E017 25.9111976 0.0010621576 0.003177225 0.10150274 2 96010613 96010624 12 + 1.520 1.322 -0.684
ENSG00000231584 E018 54.8002907 0.0116323185 0.033083223 0.29103800 2 96010625 96010722 98 + 1.814 1.670 -0.488
ENSG00000231584 E019 36.1591539 0.0148166292 0.267081666 0.67167237 2 96010723 96010732 10 + 1.609 1.527 -0.279
ENSG00000231584 E020 3.2892287 0.0066554689 0.023130724 0.25058637 2 96010733 96010851 119 + 0.771 0.422 -1.581
ENSG00000231584 E021 5.7831499 0.0044651250 0.066362546 0.38747300 2 96013724 96013729 6 + 0.697 0.932 0.923
ENSG00000231584 E022 17.7846006 0.0751993354 0.210729062 0.61506515 2 96013730 96013921 192 + 1.178 1.347 0.594
ENSG00000231584 E023 9.6707360 0.1229626707 0.230717972 0.63565398 2 96013922 96013971 50 + 0.926 1.106 0.660
ENSG00000231584 E024 32.4567075 0.0016107053 0.363919892 0.74964763 2 96015109 96015325 217 + 1.545 1.489 -0.189
ENSG00000231584 E025 38.2356669 0.0063128905 0.118429917 0.49089082 2 96019201 96019260 60 + 1.531 1.634 0.352
ENSG00000231584 E026 19.4430693 0.0079195246 0.049719546 0.34370242 2 96019261 96019274 14 + 1.219 1.386 0.585
ENSG00000231584 E027 51.6067193 0.0008653743 0.001764103 0.07462059 2 96019275 96019459 185 + 1.627 1.783 0.529
ENSG00000231584 E028 25.9341771 0.0363555774 0.028860555 0.27508779 2 96019460 96019480 21 + 1.292 1.522 0.794
ENSG00000231584 E029 46.2102173 0.0024054901 0.023801190 0.25368079 2 96019481 96019537 57 + 1.602 1.726 0.422
ENSG00000231584 E030 58.8264412 0.0008134354 0.036973819 0.30383807 2 96019538 96019627 90 + 1.720 1.817 0.329
ENSG00000231584 E031 64.1757825 0.0057839788 0.030019331 0.27966975 2 96019628 96019700 73 + 1.744 1.863 0.402
ENSG00000231584 E032 131.4853837 0.0003085383 0.792444439 0.94576729 2 96021125 96021195 71 + 2.113 2.123 0.032
ENSG00000231584 E033 114.0119855 0.0022364212 0.727377033 0.92484996 2 96021196 96021233 38 + 2.049 2.066 0.057
ENSG00000231584 E034 39.5383207 0.0023840722 0.294157415 0.69476287 2 96021234 96021367 134 + 1.628 1.570 -0.199
ENSG00000231584 E035 149.2946001 0.0002686587 0.098093060 0.45370756 2 96021368 96021465 98 + 2.196 2.152 -0.150
ENSG00000231584 E036 23.2177725 0.0036632550 0.403368623 0.77577115 2 96021598 96021834 237 + 1.346 1.409 0.219
ENSG00000231584 E037 147.1398234 0.0004261727 0.166478488 0.56252898 2 96022674 96022753 80 + 2.187 2.149 -0.128
ENSG00000231584 E038 161.3983018 0.0002132170 0.146254511 0.53390807 2 96022754 96022893 140 + 2.224 2.187 -0.124
ENSG00000231584 E039 106.8989883 0.0003131192 0.690530556 0.91196738 2 96022894 96022929 36 + 2.018 2.033 0.051
ENSG00000231584 E040 126.1956121 0.0002901626 0.998424794 0.99954674 2 96022930 96022991 62 + 2.096 2.098 0.007
ENSG00000231584 E041 177.4151887 0.0042362113 0.538112529 0.84890747 2 96022992 96023398 407 + 2.261 2.241 -0.067