ENSG00000197879

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361007 ENSG00000197879 HEK293_DMSO_6hA HEK293_OSMI2_6hA MYO1C protein_coding protein_coding 27.24635 22.48152 38.11172 1.772315 6.451119 0.761232 15.5048936 11.034747 25.3597873 1.3905188 3.7707671 1.1997511 0.5811542 0.48946667 0.67156667 0.1821 0.009640017 0.009640017 FALSE TRUE
ENST00000574308 ENSG00000197879 HEK293_DMSO_6hA HEK293_OSMI2_6hA MYO1C protein_coding retained_intron 27.24635 22.48152 38.11172 1.772315 6.451119 0.761232 0.8371631 1.676651 0.8767787 0.5212039 0.2374978 -0.9275159 0.0387375 0.07893333 0.02733333 -0.0516 0.360260338 0.009640017 FALSE FALSE
ENST00000648446 ENSG00000197879 HEK293_DMSO_6hA HEK293_OSMI2_6hA MYO1C protein_coding protein_coding 27.24635 22.48152 38.11172 1.772315 6.451119 0.761232 9.1669273 7.048367 10.6329315 1.0483779 3.2043693 0.5924893 0.3041375 0.31120000 0.26310000 -0.0481 0.747961452 0.009640017 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000197879 E001 17.9882168 0.0084578687 0.1463399467 0.53411106 17 1464186 1464211 26 - 1.213 1.342 0.451
ENSG00000197879 E002 654.9684615 0.0005573523 0.9437201851 0.98688369 17 1464212 1464841 630 - 2.807 2.809 0.006
ENSG00000197879 E003 278.8899754 0.0001705353 0.0784166747 0.41450600 17 1464842 1465016 175 - 2.454 2.414 -0.131
ENSG00000197879 E004 491.0247412 0.0021183226 0.6189701596 0.88352177 17 1465017 1465374 358 - 2.676 2.691 0.049
ENSG00000197879 E005 144.3069824 0.0096932040 0.3661083634 0.75093702 17 1465375 1465412 38 - 2.132 2.183 0.169
ENSG00000197879 E006 398.8301233 0.0019205999 0.8033894133 0.94929743 17 1465413 1465752 340 - 2.589 2.597 0.026
ENSG00000197879 E007 213.9107116 0.0001624561 0.9684361058 0.99270704 17 1467242 1467327 86 - 2.324 2.324 0.002
ENSG00000197879 E008 146.9775118 0.0002766752 0.1309417695 0.51167829 17 1467328 1467341 14 - 2.144 2.189 0.149
ENSG00000197879 E009 141.4056962 0.0004982288 0.5570611618 0.85692051 17 1467480 1467490 11 - 2.137 2.156 0.063
ENSG00000197879 E010 223.1847762 0.0001646330 0.2619941811 0.66725804 17 1467491 1467577 87 - 2.332 2.358 0.089
ENSG00000197879 E011 208.6047311 0.0002057929 0.0732016210 0.40268789 17 1467840 1467910 71 - 2.292 2.337 0.150
ENSG00000197879 E012 282.4215310 0.0011184243 0.2271761542 0.63216009 17 1467988 1468123 136 - 2.426 2.463 0.122
ENSG00000197879 E013 6.7957274 0.1059312450 0.0996564688 0.45665161 17 1468223 1468252 30 - 0.733 1.040 1.177
ENSG00000197879 E014 153.6691905 0.0002426232 0.6888018199 0.91134619 17 1468253 1468308 56 - 2.174 2.186 0.040
ENSG00000197879 E015 10.4902589 0.1054884023 0.0040591876 0.11400744 17 1468309 1468402 94 - 0.773 1.285 1.891
ENSG00000197879 E016 180.5034111 0.0002258252 0.9292805041 0.98315850 17 1468403 1468496 94 - 2.249 2.251 0.008
ENSG00000197879 E017 2.1842706 0.0089172179 0.5405680497 0.85012218 17 1468497 1468499 3 - 0.532 0.427 -0.524
ENSG00000197879 E018 8.9927794 0.0732783560 0.0219163752 0.24490931 17 1468790 1469530 741 - 0.803 1.172 1.375
ENSG00000197879 E019 179.2719940 0.0005285362 0.8783569981 0.97086836 17 1469531 1469614 84 - 2.249 2.245 -0.013
ENSG00000197879 E020 166.0275506 0.0016910525 0.6953501345 0.91352667 17 1470175 1470239 65 - 2.219 2.209 -0.034
ENSG00000197879 E021 190.0895163 0.0020084426 0.4609525192 0.80901951 17 1470240 1470334 95 - 2.279 2.260 -0.064
ENSG00000197879 E022 178.0845771 0.0007729535 0.1949145263 0.59767472 17 1470435 1470519 85 - 2.255 2.219 -0.122
ENSG00000197879 E023 114.9534097 0.0011637027 0.9277369077 0.98286180 17 1470621 1470630 10 - 2.051 2.056 0.017
ENSG00000197879 E024 170.0634072 0.0002640146 0.7213226556 0.92264615 17 1470631 1470689 59 - 2.216 2.226 0.035
ENSG00000197879 E025 2.6826532 0.1533867967 0.3301302019 0.72474487 17 1470690 1470787 98 - 0.433 0.682 1.153
ENSG00000197879 E026 173.2488564 0.0002127511 0.9844042436 0.99621886 17 1471071 1471133 63 - 2.229 2.229 0.002
ENSG00000197879 E027 107.6003747 0.0005693479 0.6989768684 0.91467786 17 1471134 1471147 14 - 2.031 2.017 -0.046
ENSG00000197879 E028 206.8928191 0.0017305565 0.4115388320 0.78140304 17 1471223 1471336 114 - 2.316 2.293 -0.077
ENSG00000197879 E029 200.8832865 0.0023528615 0.3868353546 0.76498717 17 1471907 1472024 118 - 2.304 2.279 -0.084
ENSG00000197879 E030 188.3897481 0.0001729456 0.2431868952 0.64825715 17 1472123 1472228 106 - 2.280 2.248 -0.105
ENSG00000197879 E031 3.0395491 0.1299132786 0.0002291753 0.02223444 17 1472229 1472355 127 - 0.167 0.907 3.910
ENSG00000197879 E032 181.8892554 0.0007114808 0.8302823810 0.95690313 17 1474610 1474690 81 - 2.247 2.255 0.026
ENSG00000197879 E033 184.4368994 0.0009213873 0.6886577043 0.91134619 17 1474812 1474858 47 - 2.258 2.249 -0.032
ENSG00000197879 E034 2.3855004 0.0112080623 0.1313815458 0.51236979 17 1474859 1474931 73 - 0.388 0.638 1.212
ENSG00000197879 E035 220.6593566 0.0020534803 0.8013442360 0.94873609 17 1474938 1475032 95 - 2.327 2.342 0.050
ENSG00000197879 E036 2.3432615 0.0870957567 0.4978994473 0.82837771 17 1477290 1477504 215 - 0.464 0.594 0.616
ENSG00000197879 E037 205.1091112 0.0001728344 0.1384644272 0.52300613 17 1477505 1477596 92 - 2.288 2.325 0.124
ENSG00000197879 E038 173.4988465 0.0002178568 0.9505672676 0.98843434 17 1477891 1477971 81 - 2.234 2.231 -0.009
ENSG00000197879 E039 139.2234136 0.0010026817 0.2173030935 0.62188218 17 1478087 1478192 106 - 2.154 2.111 -0.144
ENSG00000197879 E040 141.2715061 0.0004761902 0.2882891846 0.69015998 17 1478410 1478492 83 - 2.161 2.126 -0.116
ENSG00000197879 E041 147.0422761 0.0002470301 0.4579149608 0.80748127 17 1478616 1478676 61 - 2.173 2.150 -0.077
ENSG00000197879 E042 150.5232823 0.0002496076 0.2937268770 0.69444240 17 1478677 1478735 59 - 2.183 2.151 -0.106
ENSG00000197879 E043 162.9160609 0.0008732499 0.1717670837 0.56925377 17 1479431 1479502 72 - 2.222 2.180 -0.139
ENSG00000197879 E044 200.9923260 0.0014866983 0.6322627078 0.88888101 17 1479592 1479685 94 - 2.299 2.287 -0.039
ENSG00000197879 E045 117.2739587 0.0002922447 0.3800039294 0.76016552 17 1479686 1479705 20 - 2.049 2.078 0.099
ENSG00000197879 E046 197.3760653 0.0001669160 0.8968058267 0.97547436 17 1480527 1480606 80 - 2.286 2.289 0.010
ENSG00000197879 E047 119.3251186 0.0002495805 0.7228541270 0.92315298 17 1480607 1480625 19 - 2.077 2.065 -0.041
ENSG00000197879 E048 241.7554201 0.0001482053 0.6174165527 0.88291331 17 1480706 1480885 180 - 2.379 2.367 -0.040
ENSG00000197879 E049 0.8852955 0.0197758049 0.1369428527   17 1480886 1480984 99 - 0.170 0.427 1.804
ENSG00000197879 E050 0.3340335 0.0265284958 0.0902663652   17 1480985 1481158 174 - 0.000 0.264 12.208
ENSG00000197879 E051 0.8056957 0.0905985453 0.0635089181   17 1481159 1481238 80 - 0.093 0.428 2.816
ENSG00000197879 E052 98.8770478 0.0003000689 0.9590094615 0.99057832 17 1482478 1482488 11 - 1.988 1.990 0.005
ENSG00000197879 E053 124.8213192 0.0002667428 0.5255866803 0.84287600 17 1482489 1482532 44 - 2.100 2.078 -0.072
ENSG00000197879 E054 96.9872176 0.0003332080 0.3711298809 0.75401613 17 1482533 1482558 26 - 1.996 1.963 -0.113
ENSG00000197879 E055 84.0298662 0.0003661947 0.3761172724 0.75738637 17 1482861 1482888 28 - 1.934 1.899 -0.120
ENSG00000197879 E056 207.2443639 0.0003491932 0.6613084531 0.90093117 17 1482889 1483059 171 - 2.302 2.314 0.041
ENSG00000197879 E057 170.2828680 0.0002025070 0.4128452142 0.78227240 17 1483610 1483725 116 - 2.213 2.236 0.076
ENSG00000197879 E058 152.4738319 0.0003271361 0.5236389413 0.84189929 17 1484148 1484303 156 - 2.181 2.162 -0.063
ENSG00000197879 E059 0.5419930 0.2980432277 0.9768856850   17 1484590 1484657 68 - 0.176 0.153 -0.246
ENSG00000197879 E060 1.1369270 0.0616066998 0.0789255440   17 1485122 1485367 246 - 0.170 0.490 2.125
ENSG00000197879 E061 9.0622526 0.0282162128 0.7654244853 0.93776000 17 1485694 1485762 69 - 1.011 0.973 -0.140
ENSG00000197879 E062 1.0052485 0.0724885632 0.0445345613   17 1486055 1486201 147 - 0.392 0.000 -13.021
ENSG00000197879 E063 0.1795728 0.0329889968 0.2870813181   17 1486880 1486951 72 - 0.000 0.152 11.129
ENSG00000197879 E064 3.3494942 0.0280969538 0.2757185639 0.67938452 17 1486952 1487098 147 - 0.535 0.715 0.786
ENSG00000197879 E065 2.8144218 0.0076502618 0.0375669886 0.30581696 17 1490928 1491237 310 - 0.428 0.748 1.456
ENSG00000197879 E066 48.7947105 0.0022481073 0.0891205779 0.43674460 17 1491600 1491682 83 - 1.721 1.628 -0.315
ENSG00000197879 E067 0.0000000       17 1492010 1492040 31 -      
ENSG00000197879 E068 0.9517497 0.5738360667 0.9149712293   17 1492413 1492686 274 - 0.300 0.259 -0.284