ENSG00000197122

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373567 ENSG00000197122 HEK293_DMSO_6hA HEK293_OSMI2_6hA SRC protein_coding protein_coding 9.675989 9.126351 14.14527 0.8994672 1.787033 0.6316489 0.5607879 0.7308669 0.0000000 0.7308669 0.0000000 -6.2111425 0.06737917 0.08286667 0.0000000 -0.082866667 0.7517378183 0.0006821964 FALSE  
ENST00000373578 ENSG00000197122 HEK293_DMSO_6hA HEK293_OSMI2_6hA SRC protein_coding protein_coding 9.675989 9.126351 14.14527 0.8994672 1.787033 0.6316489 5.5735136 3.9779968 9.0123669 0.6286889 1.9423064 1.1778417 0.57211250 0.43090000 0.6206333 0.189733333 0.2108037801 0.0006821964 FALSE  
ENST00000467556 ENSG00000197122 HEK293_DMSO_6hA HEK293_OSMI2_6hA SRC protein_coding retained_intron 9.675989 9.126351 14.14527 0.8994672 1.787033 0.6316489 0.4644209 0.9716432 0.6127666 0.1656913 0.2217402 -0.6565071 0.05700417 0.11000000 0.0496000 -0.060400000 0.4375874385 0.0006821964 FALSE  
ENST00000489153 ENSG00000197122 HEK293_DMSO_6hA HEK293_OSMI2_6hA SRC protein_coding retained_intron 9.675989 9.126351 14.14527 0.8994672 1.787033 0.6316489 0.1450657 0.5478247 0.0000000 0.2508950 0.0000000 -5.8017399 0.01672917 0.05783333 0.0000000 -0.057833333 0.0006821964 0.0006821964 FALSE  
MSTRG.20680.2 ENSG00000197122 HEK293_DMSO_6hA HEK293_OSMI2_6hA SRC protein_coding   9.675989 9.126351 14.14527 0.8994672 1.787033 0.6316489 1.7611615 1.6060603 2.5517176 0.2854496 0.3418552 0.6646304 0.16727917 0.17470000 0.1803333 0.005633333 0.9652039691 0.0006821964 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000197122 E001 0.0000000       20 37344685 37344887 203 +      
ENSG00000197122 E002 9.0310510 0.0031644338 0.094935234 0.44796465 20 37346087 37346108 22 + 1.060 0.880 -0.668
ENSG00000197122 E003 14.7570866 0.0019030211 0.196568504 0.59978771 20 37346109 37346139 31 + 1.232 1.126 -0.378
ENSG00000197122 E004 42.0204020 0.0006851782 0.034032663 0.29398522 20 37346140 37346255 116 + 1.663 1.557 -0.363
ENSG00000197122 E005 2.6649602 0.0112410203 0.772371310 0.94008340 20 37347118 37347236 119 + 0.536 0.589 0.241
ENSG00000197122 E006 48.1578998 0.0005965797 0.032486012 0.28906323 20 37365204 37365277 74 + 1.721 1.621 -0.339
ENSG00000197122 E007 62.1391449 0.0004530319 0.021699284 0.24394618 20 37382619 37382786 168 + 1.828 1.734 -0.317
ENSG00000197122 E008 0.4979971 0.0252391259 0.032349176   20 37382787 37382787 1 + 0.000 0.350 13.684
ENSG00000197122 E009 0.1795728 0.0335753759 0.302247438   20 37383668 37383702 35 + 0.000 0.150 12.011
ENSG00000197122 E010 0.9349177 0.1388294583 0.309204236   20 37383757 37383874 118 + 0.347 0.150 -1.563
ENSG00000197122 E011 50.5560165 0.0047829045 0.077917002 0.41338398 20 37384150 37384322 173 + 1.732 1.643 -0.302
ENSG00000197122 E012 41.0896448 0.0061916571 0.385780695 0.76435187 20 37384323 37384403 81 + 1.625 1.582 -0.148
ENSG00000197122 E013 74.2207971 0.0004433715 0.435023188 0.79442794 20 37386075 37386174 100 + 1.875 1.854 -0.071
ENSG00000197122 E014 1.2295676 0.1331676262 0.833879455   20 37386460 37386477 18 + 0.303 0.350 0.299
ENSG00000197122 E015 4.0059437 0.0055915607 0.540238469 0.85000478 20 37387431 37387801 371 + 0.645 0.743 0.411
ENSG00000197122 E016 0.0000000       20 37392983 37393015 33 +      
ENSG00000197122 E017 1.9706558 0.0095600922 0.001418236 0.06607096 20 37393745 37393894 150 + 0.172 0.709 3.080
ENSG00000197122 E018 83.3352821 0.0004131493 0.938996369 0.98565489 20 37393895 37393993 99 + 1.916 1.924 0.027
ENSG00000197122 E019 0.3513410 0.0244411696 0.098569423   20 37393994 37394173 180 + 0.000 0.261 13.124
ENSG00000197122 E020 87.1279449 0.0006279252 0.321726837 0.71811735 20 37394174 37394277 104 + 1.917 1.966 0.167
ENSG00000197122 E021 101.6633331 0.0009396981 0.854146800 0.96393040 20 37396162 37396311 150 + 2.002 2.007 0.018
ENSG00000197122 E022 0.1544607 0.0538621110 0.302566994   20 37396426 37396774 349 + 0.000 0.150 11.805
ENSG00000197122 E023 114.9341527 0.0003414575 0.988404062 0.99714743 20 37397699 37397854 156 + 2.048 2.060 0.042
ENSG00000197122 E024 67.3657967 0.0086980103 0.634594966 0.88998065 20 37400115 37400148 34 + 1.801 1.856 0.186
ENSG00000197122 E025 104.2114812 0.0003316566 0.353035838 0.74189281 20 37400149 37400250 102 + 1.990 2.034 0.148
ENSG00000197122 E026 87.9169843 0.0012068087 0.778087462 0.94178116 20 37400251 37400294 44 + 1.933 1.935 0.005
ENSG00000197122 E027 89.0272576 0.0003265544 0.889951300 0.97360107 20 37401602 37401678 77 + 1.938 1.955 0.054
ENSG00000197122 E028 7.5280161 0.3136200313 0.098438092 0.45441340 20 37401679 37401829 151 + 0.703 1.119 1.586
ENSG00000197122 E029 16.6668481 0.2060196770 0.055225958 0.35897848 20 37401830 37402292 463 + 1.051 1.419 1.300
ENSG00000197122 E030 6.3830644 0.4436690686 0.221270933 0.62573480 20 37402313 37402434 122 + 0.760 0.969 0.803
ENSG00000197122 E031 104.2681882 0.0005662665 0.391743225 0.76805531 20 37402435 37402588 154 + 2.018 2.000 -0.062
ENSG00000197122 E032 102.5805065 0.0014041638 0.348124273 0.73798213 20 37402749 37402880 132 + 2.012 1.987 -0.083
ENSG00000197122 E033 5.2502915 0.0387748854 0.081570026 0.42094013 20 37402881 37403031 151 + 0.648 0.925 1.104
ENSG00000197122 E034 820.4254242 0.0037109785 0.379041129 0.75943247 20 37403171 37406050 2880 + 2.891 2.925 0.112