ENSG00000184007

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-8 / 8
Columns:
Select all:
isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000457805	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	protein_coding	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	28.428967	9.803384	3.184006	3.629218	1.861439	-1.6193836	0.15851250	0.12593333	0.03273333	-0.09320000	5.924820e-01	2.089506e-06	FALSE	TRUE
ENST00000468531	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	protein_coding	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	2.865961	0.000000	4.918026	0.000000	2.865997	8.9448659	0.01726667	0.00000000	0.05060000	0.05060000	3.559576e-01	2.089506e-06		FALSE
ENST00000528840	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	processed_transcript	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	10.633684	5.018966	0.000000	2.557649	0.000000	-8.9741181	0.05915000	0.07176667	0.00000000	-0.07176667	3.983205e-01	2.089506e-06		FALSE
ENST00000529477	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	processed_transcript	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	15.283671	7.911730	0.000000	4.414684	0.000000	-9.6296716	0.07765833	0.09013333	0.00000000	-0.09013333	3.750417e-01	2.089506e-06		FALSE
ENST00000602683	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	protein_coding	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	19.288976	5.458789	12.046228	1.393273	2.322116	1.1404852	0.12518750	0.07376667	0.15793333	0.08416667	2.089506e-06	2.089506e-06	FALSE	TRUE
ENST00000602725	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	protein_coding	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	31.735706	27.234121	18.474545	6.968569	5.033318	-0.5596254	0.22407917	0.36830000	0.23163333	-0.13666667	1.546068e-01	2.089506e-06	FALSE	TRUE
ENST00000647444	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding	protein_coding	157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	29.954887	7.797963	10.697072	1.748265	2.053292	0.4555459	0.18012917	0.10950000	0.13953333	0.03003333	5.855622e-01	2.089506e-06	FALSE	TRUE
MSTRG.747.5	ENSG00000184007	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	PTP4A2	protein_coding		157.2186	74.22953	78.83451	19.41217	18.22844	0.08682261	9.615138	8.503111	23.012748	1.241147	3.637150	1.4353018	0.09719583	0.12466667	0.31073333	0.18606667	3.223585e-03	2.089506e-06	FALSE	FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 41
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_OSMI2_6hA
HEK293_DMSO_6hA
log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_OSMI2_6hA	HEK293_DMSO_6hA	log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA

ENSG00000184007	E001	1649.8220422	0.0061611246	3.343041e-07	0.0002552867	1	31906421	31908262	1842	-	3.102	3.306	0.678
ENSG00000184007	E002	305.2265057	0.0001676142	1.369856e-07	0.0001289758	1	31908263	31908533	271	-	2.414	2.552	0.459
ENSG00000184007	E003	135.7837017	0.0066585011	1.590338e-02	0.2143348030	1	31908534	31908585	52	-	2.056	2.202	0.488
ENSG00000184007	E004	163.8629557	0.0066492143	2.317804e-02	0.2508154079	1	31908586	31908652	67	-	2.141	2.280	0.465
ENSG00000184007	E005	99.7178484	0.0005160183	1.731351e-03	0.0738955271	1	31908653	31908657	5	-	1.926	2.069	0.481
ENSG00000184007	E006	276.3091610	0.0006607423	2.255122e-02	0.2479128593	1	31908658	31908707	50	-	2.399	2.483	0.280
ENSG00000184007	E007	555.2775769	0.0000992763	4.190408e-01	0.7856041834	1	31908708	31908838	131	-	2.727	2.769	0.140
ENSG00000184007	E008	689.1131446	0.0001254095	4.906959e-01	0.8248354122	1	31908839	31908960	122	-	2.832	2.853	0.070
ENSG00000184007	E009	429.4815328	0.0001243522	3.682112e-01	0.7522611932	1	31910038	31910068	31	-	2.631	2.645	0.048
ENSG00000184007	E010	441.9827847	0.0001107044	1.656910e-02	0.2180297248	1	31910069	31910112	44	-	2.656	2.645	-0.035
ENSG00000184007	E011	5.7680162	0.0212803783	1.960927e-01	0.5992151541	1	31910113	31911280	1168	-	0.719	0.919	0.787
ENSG00000184007	E012	694.0698648	0.0004095158	5.736523e-03	0.1350767247	1	31911696	31911826	131	-	2.853	2.838	-0.050
ENSG00000184007	E013	1.6504427	0.0120886095	5.148736e-01	0.8375541167	1	31912981	31913023	43	-	0.345	0.475	0.712
ENSG00000184007	E014	1.2439656	0.0507868205	3.555836e-02		1	31913787	31913843	57	-	0.114	0.520	2.937
ENSG00000184007	E015	1.7607199	0.0171613303	3.796089e-01	0.7599286488	1	31915540	31915894	355	-	0.495	0.366	-0.683
ENSG00000184007	E016	353.7943216	0.0006918710	4.065277e-02	0.3164175306	1	31915895	31915987	93	-	2.562	2.546	-0.052
ENSG00000184007	E017	320.0490824	0.0007535862	2.509704e-02	0.2590919372	1	31918970	31918999	30	-	2.522	2.499	-0.077
ENSG00000184007	E018	477.8496221	0.0010677405	4.956103e-04	0.0358582397	1	31919000	31919093	94	-	2.708	2.660	-0.162
ENSG00000184007	E019	300.9050061	0.0009610028	7.777534e-05	0.0117388228	1	31919094	31919129	36	-	2.519	2.450	-0.230
ENSG00000184007	E020	344.3888892	0.0015404644	9.142559e-06	0.0028639021	1	31919130	31919228	99	-	2.585	2.497	-0.293
ENSG00000184007	E021	191.9364883	0.0006838560	7.398059e-06	0.0024766160	1	31919229	31919243	15	-	2.336	2.241	-0.317
ENSG00000184007	E022	171.3325466	0.0007499579	2.348611e-05	0.0054179995	1	31919244	31919246	3	-	2.286	2.192	-0.314
ENSG00000184007	E023	163.0633663	0.0019281058	2.320343e-04	0.0224330088	1	31919247	31919259	13	-	2.265	2.170	-0.318
ENSG00000184007	E024	482.8945301	0.0003340044	6.015838e-03	0.1375812724	1	31919260	31919423	164	-	2.697	2.679	-0.060
ENSG00000184007	E025	479.1472152	0.0002226642	6.053842e-03	0.1381214567	1	31919424	31919562	139	-	2.693	2.677	-0.054
ENSG00000184007	E026	174.8774665	0.0084686427	3.046634e-01	0.7035829713	1	31919563	31919568	6	-	2.257	2.239	-0.058
ENSG00000184007	E027	231.8333003	0.0049027471	8.597866e-02	0.4299296295	1	31919569	31919658	90	-	2.387	2.351	-0.120
ENSG00000184007	E028	1.2073187	0.0724604626	2.747735e-01		1	31924018	31924165	148	-	0.207	0.425	1.439
ENSG00000184007	E029	0.3340335	0.0274424043	2.012164e-01		1	31930039	31930334	296	-	0.000	0.221	13.108
ENSG00000184007	E030	3.9441892	0.0072389510	7.278505e-01	0.9249765547	1	31930933	31931142	210	-	0.694	0.667	-0.114
ENSG00000184007	E031	0.6602624	0.0186694085	3.692599e-02		1	31932672	31932700	29	-	0.000	0.366	14.108
ENSG00000184007	E032	2.3196058	0.1282573546	9.319770e-01	0.9838019876	1	31935589	31935659	71	-	0.504	0.519	0.069
ENSG00000184007	E033	0.1767706	0.0739448135	4.937248e-01		1	31937755	31937777	23	-	0.115	0.000	-12.021
ENSG00000184007	E034	0.1767706	0.0739448135	4.937248e-01		1	31937778	31937841	64	-	0.115	0.000	-12.021
ENSG00000184007	E035	0.3624201	0.3911194051	3.008826e-01		1	31937842	31937986	145	-	0.214	0.000	-13.065
ENSG00000184007	E036	143.7323887	0.0002208621	1.729548e-05	0.0044629940	1	31937987	31938059	73	-	2.209	2.113	-0.323
ENSG00000184007	E037	53.5194268	0.0056692050	4.763208e-02	0.3374959065	1	31938060	31938118	59	-	1.780	1.693	-0.296
ENSG00000184007	E038	48.0872268	0.0088178789	1.615786e-03	0.0711534308	1	31938119	31938262	144	-	1.785	1.592	-0.657
ENSG00000184007	E039	30.2722875	0.0033976075	7.008554e-05	0.0109979210	1	31938263	31938368	106	-	1.611	1.366	-0.842
ENSG00000184007	E040	0.0000000				1	31942529	31942576	48	-
ENSG00000184007	E041	0.2892872	0.0260983465	2.071968e-01		1	31944593	31944856	264	-	0.206	0.000	-13.015

Isoforom Switch Analysis

WANG Ziyi

Date: 18 5月 2022

ENSG00000184007

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3