ENSG00000179832

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000326134 ENSG00000179832 HEK293_DMSO_6hA HEK293_OSMI2_6hA MROH1 protein_coding protein_coding 5.044279 5.537516 7.141614 0.2773757 0.5931692 0.3664269 0.8643727 0.7396406 1.3551365 0.11269041 0.28254146 0.8647741 0.19002917 0.13353333 0.18613333 0.05260000 0.7248157 0.043742 FALSE TRUE
ENST00000423230 ENSG00000179832 HEK293_DMSO_6hA HEK293_OSMI2_6hA MROH1 protein_coding protein_coding 5.044279 5.537516 7.141614 0.2773757 0.5931692 0.3664269 1.3301853 0.9923811 1.8929172 0.15811316 0.45417051 0.9247816 0.28985833 0.17823333 0.26450000 0.08626667 0.7250794 0.043742 FALSE TRUE
ENST00000527071 ENSG00000179832 HEK293_DMSO_6hA HEK293_OSMI2_6hA MROH1 protein_coding processed_transcript 5.044279 5.537516 7.141614 0.2773757 0.5931692 0.3664269 0.3384288 0.3936609 0.6677365 0.13652689 0.27478590 0.7475807 0.06510000 0.07293333 0.08880000 0.01586667 0.8751117 0.043742   FALSE
ENST00000528664 ENSG00000179832 HEK293_DMSO_6hA HEK293_OSMI2_6hA MROH1 protein_coding retained_intron 5.044279 5.537516 7.141614 0.2773757 0.5931692 0.3664269 0.4484000 0.8684139 0.2243912 0.15638599 0.07638479 -1.9059824 0.05927500 0.15656667 0.03240000 -0.12416667 0.0437420 0.043742 FALSE FALSE
ENST00000532255 ENSG00000179832 HEK293_DMSO_6hA HEK293_OSMI2_6hA MROH1 protein_coding retained_intron 5.044279 5.537516 7.141614 0.2773757 0.5931692 0.3664269 0.7616702 1.1059168 1.2045191 0.10098837 0.13227615 0.1221558 0.17125833 0.19900000 0.16850000 -0.03050000 0.7570140 0.043742 FALSE TRUE
MSTRG.32248.21 ENSG00000179832 HEK293_DMSO_6hA HEK293_OSMI2_6hA MROH1 protein_coding   5.044279 5.537516 7.141614 0.2773757 0.5931692 0.3664269 0.1764423 0.1364054 0.5489006 0.06892137 0.04268439 1.9326235 0.04805417 0.02430000 0.07716667 0.05286667 0.3406878 0.043742 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000179832 E001 0.5136063 0.0437299164 0.0623588447   8 144148016 144148016 1 + 0.000 0.312 13.135
ENSG00000179832 E002 0.6261229 0.0299059392 0.2352099673   8 144148017 144148018 2 + 0.109 0.312 1.877
ENSG00000179832 E003 0.7386395 0.0961180272 0.5169516489   8 144148019 144148026 8 + 0.194 0.312 0.898
ENSG00000179832 E004 1.9992232 0.0092399822 0.5406897516 0.85024538 8 144148027 144148029 3 + 0.434 0.538 0.513
ENSG00000179832 E005 2.1709914 0.0090409342 0.3817986865 0.76141480 8 144148030 144148030 1 + 0.434 0.580 0.705
ENSG00000179832 E006 2.6320467 0.0078095413 0.5334549629 0.84693416 8 144148031 144148035 5 + 0.517 0.618 0.460
ENSG00000179832 E007 2.9900274 0.0066686454 0.8586861416 0.96531136 8 144148036 144148037 2 + 0.587 0.618 0.137
ENSG00000179832 E008 2.9900274 0.0066686454 0.8586861416 0.96531136 8 144148038 144148040 3 + 0.587 0.618 0.137
ENSG00000179832 E009 16.1512781 0.0015752515 0.2712403934 0.67538654 8 144148041 144148076 36 + 1.274 1.186 -0.309
ENSG00000179832 E010 1.2744650 0.0504373397 0.6631854525   8 144148645 144148712 68 + 0.387 0.312 -0.453
ENSG00000179832 E011 0.1767706 0.0331461533 0.5719013309   8 144148810 144148882 73 + 0.110 0.000 -11.179
ENSG00000179832 E012 9.2193373 0.0028325053 0.4003592895 0.77353196 8 144160970 144160995 26 + 0.969 1.061 0.337
ENSG00000179832 E013 13.6493729 0.0020960515 0.4499357750 0.80347790 8 144160996 144161024 29 + 1.134 1.206 0.256
ENSG00000179832 E014 16.1883497 0.0017430941 0.6478061508 0.89564692 8 144161025 144161089 65 + 1.217 1.259 0.149
ENSG00000179832 E015 33.1798477 0.0009155128 0.2800560854 0.68321969 8 144163771 144163848 78 + 1.553 1.493 -0.206
ENSG00000179832 E016 44.8224550 0.0027873152 0.0756698844 0.40830062 8 144168295 144168440 146 + 1.698 1.605 -0.316
ENSG00000179832 E017 45.7965120 0.0029033515 0.1955161888 0.59843721 8 144179455 144179586 132 + 1.701 1.634 -0.226
ENSG00000179832 E018 43.8054066 0.0082784406 0.0033159612 0.10370907 8 144180178 144180340 163 + 1.732 1.540 -0.651
ENSG00000179832 E019 33.6016922 0.0016107760 0.0003593710 0.02942243 8 144180425 144180523 99 + 1.624 1.407 -0.744
ENSG00000179832 E020 52.6759812 0.0006552461 0.0110000279 0.18155415 8 144190784 144190935 152 + 1.779 1.661 -0.399
ENSG00000179832 E021 46.6929633 0.0022418344 0.0907644381 0.43989897 8 144191715 144191855 141 + 1.718 1.631 -0.297
ENSG00000179832 E022 39.7034538 0.0013789933 0.0147327164 0.20698124 8 144192309 144192401 93 + 1.668 1.535 -0.453
ENSG00000179832 E023 1.8984096 0.0097811804 0.8030353796 0.94918977 8 144192402 144193282 881 + 0.478 0.439 -0.198
ENSG00000179832 E024 0.6697652 0.0793607801 0.0315117383   8 144199119 144199121 3 + 0.000 0.380 13.583
ENSG00000179832 E025 30.7036750 0.0071302249 0.0823935354 0.42270982 8 144199122 144199200 79 + 1.550 1.431 -0.410
ENSG00000179832 E026 33.7868231 0.0237511096 0.1861681597 0.58690372 8 144200428 144200541 114 + 1.589 1.475 -0.389
ENSG00000179832 E027 0.4688600 0.0217681645 0.6841477759   8 144200542 144201179 638 + 0.197 0.130 -0.711
ENSG00000179832 E028 21.6067999 0.0470239331 0.8855364191 0.97266854 8 144212994 144213467 474 + 1.350 1.352 0.009
ENSG00000179832 E029 6.7293959 0.1137377339 0.7938525394 0.94612670 8 144214006 144214489 484 + 0.934 0.861 -0.276
ENSG00000179832 E030 21.5760067 0.0020313253 0.2290826660 0.63423400 8 144220600 144220673 74 + 1.385 1.299 -0.299
ENSG00000179832 E031 25.7211404 0.0010779012 0.4925436268 0.82572305 8 144223108 144223230 123 + 1.442 1.401 -0.143
ENSG00000179832 E032 22.7481117 0.0013050348 0.0932898893 0.44459389 8 144238756 144238863 108 + 1.424 1.307 -0.407
ENSG00000179832 E033 18.9335546 0.0125565019 0.0686751947 0.39287640 8 144239035 144239111 77 + 1.363 1.196 -0.583
ENSG00000179832 E034 20.6880473 0.0353289700 0.7966732372 0.94718587 8 144239112 144239179 68 + 1.353 1.300 -0.184
ENSG00000179832 E035 20.1691128 0.0395823858 0.8373061583 0.95945154 8 144239323 144239363 41 + 1.330 1.303 -0.095
ENSG00000179832 E036 29.3134084 0.0206082501 0.8860674910 0.97277786 8 144239614 144239755 142 + 1.467 1.485 0.063
ENSG00000179832 E037 2.1803432 0.0090703950 0.0223674917 0.24730137 8 144239756 144239766 11 + 0.270 0.654 2.024
ENSG00000179832 E038 21.4316816 0.0370334740 0.7723639317 0.94008340 8 144240101 144240153 53 + 1.370 1.328 -0.145
ENSG00000179832 E039 29.9147557 0.0131137781 0.8205567251 0.95461840 8 144240570 144240677 108 + 1.498 1.478 -0.066
ENSG00000179832 E040 32.8772263 0.0209990192 0.6857129938 0.91019870 8 144240992 144241111 120 + 1.512 1.544 0.107
ENSG00000179832 E041 28.3084427 0.0010037269 0.6096645956 0.87980255 8 144241395 144241517 123 + 1.481 1.452 -0.099
ENSG00000179832 E042 3.9096935 0.1770498952 0.0990414522 0.45544776 8 144242211 144242368 158 + 0.496 0.818 1.388
ENSG00000179832 E043 31.7904328 0.0010791511 0.1915518616 0.59367754 8 144242369 144242515 147 + 1.472 1.557 0.289
ENSG00000179832 E044 1.0064135 0.0197526707 0.5567774576   8 144242602 144242628 27 + 0.333 0.231 -0.715
ENSG00000179832 E045 32.4086307 0.0010967903 0.3021802937 0.70157728 8 144243494 144243616 123 + 1.489 1.557 0.232
ENSG00000179832 E046 26.9828270 0.0035126216 0.9001964131 0.97623958 8 144243863 144243942 80 + 1.443 1.441 -0.005
ENSG00000179832 E047 33.8941824 0.0043210192 0.4513929825 0.80431623 8 144244222 144244336 115 + 1.555 1.512 -0.146
ENSG00000179832 E048 31.2371758 0.0010303820 0.8353834000 0.95866406 8 144244444 144244539 96 + 1.490 1.507 0.061
ENSG00000179832 E049 33.8344054 0.0009742977 0.0854548234 0.42909628 8 144245156 144245260 105 + 1.577 1.478 -0.339
ENSG00000179832 E050 40.5846569 0.0007232189 0.1249882069 0.50236904 8 144247301 144247436 136 + 1.652 1.573 -0.270
ENSG00000179832 E051 41.4730006 0.0009384828 0.3640367276 0.74968953 8 144247567 144247679 113 + 1.605 1.658 0.179
ENSG00000179832 E052 46.3616634 0.0006643894 0.4393542143 0.79726059 8 144248877 144249029 153 + 1.652 1.696 0.149
ENSG00000179832 E053 45.3927956 0.0007891070 0.0373185970 0.30493494 8 144250212 144250366 155 + 1.608 1.720 0.378
ENSG00000179832 E054 80.5206156 0.0003542700 0.0006697489 0.04336984 8 144250367 144252668 2302 + 1.837 1.972 0.454
ENSG00000179832 E055 8.0911719 0.0596643128 0.0015936211 0.07042181 8 144254422 144254812 391 + 0.653 1.143 1.882
ENSG00000179832 E056 30.5444750 0.0209419200 0.1404383271 0.52589146 8 144254813 144254978 166 + 1.424 1.563 0.478
ENSG00000179832 E057 4.2355647 0.0056740913 0.9312738159 0.98362396 8 144254979 144255508 530 + 0.724 0.716 -0.034
ENSG00000179832 E058 25.2463281 0.0011732906 0.1206582624 0.49492945 8 144255509 144255705 197 + 1.358 1.468 0.379
ENSG00000179832 E059 6.7306476 0.0186135344 0.0018816236 0.07714051 8 144255706 144256521 816 + 0.647 1.060 1.610
ENSG00000179832 E060 12.7411685 0.1433628292 0.0269912128 0.26688268 8 144256522 144258373 1852 + 0.904 1.294 1.412
ENSG00000179832 E061 5.3361461 0.1274193091 0.3186713814 0.71560507 8 144258374 144258776 403 + 0.709 0.880 0.676
ENSG00000179832 E062 21.8972657 0.0063753653 0.3741444538 0.75601812 8 144258777 144258914 138 + 1.313 1.390 0.265
ENSG00000179832 E063 6.3507888 0.0043591688 0.0017329464 0.07391630 8 144258915 144259239 325 + 0.619 1.019 1.582
ENSG00000179832 E064 20.1806946 0.0082448090 0.2188822533 0.62354071 8 144259240 144259354 115 + 1.262 1.370 0.377
ENSG00000179832 E065 7.2852415 0.2423244901 0.6045667021 0.87741898 8 144259355 144259822 468 + 0.890 0.930 0.150
ENSG00000179832 E066 2.0542300 0.1960232168 0.3262381763 0.72173205 8 144259823 144259910 88 + 0.572 0.313 -1.369
ENSG00000179832 E067 21.3400894 0.0023275375 0.1432528252 0.52987238 8 144259911 144260057 147 + 1.287 1.401 0.396
ENSG00000179832 E068 3.3028836 0.0556332225 0.0063546419 0.14098467 8 144260058 144260185 128 + 0.333 0.819 2.275
ENSG00000179832 E069 22.5254690 0.0151542174 0.3401366813 0.73203571 8 144260186 144260374 189 + 1.316 1.409 0.322
ENSG00000179832 E070 6.6422370 0.2274736966 0.3479051016 0.73776290 8 144260375 144260462 88 + 0.831 0.923 0.353
ENSG00000179832 E071 4.2063640 0.2215741478 0.7328399243 0.92665574 8 144260463 144260482 20 + 0.712 0.714 0.008
ENSG00000179832 E072 8.0179713 0.2225177990 0.2240360199 0.62887124 8 144260483 144260676 194 + 0.831 1.058 0.853
ENSG00000179832 E073 22.3126779 0.0387865417 0.2391632666 0.64439352 8 144260677 144260832 156 + 1.286 1.439 0.529
ENSG00000179832 E074 3.6053923 0.0064111012 0.2032947144 0.60717525 8 144260833 144260906 74 + 0.554 0.744 0.817
ENSG00000179832 E075 18.3170869 0.0015622511 0.1522837773 0.54235713 8 144260907 144261041 135 + 1.218 1.336 0.415
ENSG00000179832 E076 0.1717682 0.0323400037 0.4142936140   8 144261042 144261113 72 + 0.000 0.130 11.583
ENSG00000179832 E077 12.2912295 0.0402519228 0.6842934538 0.90972330 8 144261114 144261216 103 + 1.157 1.101 -0.203
ENSG00000179832 E078 3.0722783 0.0066374397 0.1245602644 0.50146381 8 144261217 144261283 67 + 0.478 0.716 1.065
ENSG00000179832 E079 13.1397020 0.0219110318 0.5438093726 0.85162878 8 144261284 144261349 66 + 1.194 1.123 -0.254
ENSG00000179832 E080 2.7061686 0.2208892924 0.3933655534 0.76901214 8 144261350 144261654 305 + 0.466 0.681 0.981
ENSG00000179832 E081 21.6978411 0.0075396638 0.5487249805 0.85339766 8 144261655 144261927 273 + 1.377 1.336 -0.143