ENSG00000178234

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000430044 ENSG00000178234 HEK293_DMSO_6hA HEK293_OSMI2_6hA GALNT11 protein_coding protein_coding 20.17907 15.87588 12.73015 2.941374 0.5469714 -0.318362 14.274025 9.7834337 10.3131968 2.6388233 0.4297344 0.07600312 0.71462917 0.59683333 0.81073333 0.21390000 0.008636143 0.008636143 FALSE TRUE
MSTRG.30952.1 ENSG00000178234 HEK293_DMSO_6hA HEK293_OSMI2_6hA GALNT11 protein_coding   20.17907 15.87588 12.73015 2.941374 0.5469714 -0.318362 2.216351 1.6512368 0.8996564 0.4505657 0.2939064 -0.86886414 0.10508333 0.11066667 0.07150000 -0.03916667 0.743241066 0.008636143 FALSE TRUE
MSTRG.30952.5 ENSG00000178234 HEK293_DMSO_6hA HEK293_OSMI2_6hA GALNT11 protein_coding   20.17907 15.87588 12.73015 2.941374 0.5469714 -0.318362 1.420233 1.0629114 0.4270051 0.4055874 0.1821943 -1.29580883 0.06649583 0.06390000 0.03283333 -0.03106667 0.619879767 0.008636143 FALSE TRUE
MSTRG.30952.9 ENSG00000178234 HEK293_DMSO_6hA HEK293_OSMI2_6hA GALNT11 protein_coding   20.17907 15.87588 12.73015 2.941374 0.5469714 -0.318362 0.330512 0.9449227 0.0000000 0.4745984 0.0000000 -6.57731200 0.01542083 0.05396667 0.00000000 -0.05396667 0.237661894 0.008636143 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000178234 E001 0.5247464 0.4204902670 0.8007672610   7 152025663 152025673 11 + 0.135 0.195 0.637
ENSG00000178234 E002 3.3626034 0.0065307596 0.0020129169 0.07994824 7 152025674 152025694 21 + 0.848 0.383 -2.095
ENSG00000178234 E003 3.8342656 0.0063716489 0.0062653591 0.14022507 7 152025695 152025697 3 + 0.869 0.474 -1.691
ENSG00000178234 E004 8.0908566 0.0308164008 0.0038952442 0.11159700 7 152025698 152025713 16 + 1.138 0.744 -1.487
ENSG00000178234 E005 14.7211046 0.0019308658 0.0018984325 0.07752276 7 152025714 152025741 28 + 1.327 1.059 -0.954
ENSG00000178234 E006 21.9406822 0.0012654369 0.0027610787 0.09427892 7 152025742 152025775 34 + 1.469 1.254 -0.746
ENSG00000178234 E007 26.9114311 0.0011527671 0.0458174168 0.33227445 7 152025776 152025797 22 + 1.509 1.378 -0.451
ENSG00000178234 E008 48.4175972 0.0005426052 0.0011505403 0.05868110 7 152025798 152025884 87 + 1.773 1.614 -0.539
ENSG00000178234 E009 4.3484217 0.0295618667 0.1370044021 0.52089641 7 152027597 152027669 73 + 0.583 0.821 0.993
ENSG00000178234 E010 5.5167058 0.0105987869 0.7294212109 0.92541394 7 152027670 152027718 49 + 0.777 0.823 0.181
ENSG00000178234 E011 0.0000000       7 152074298 152074403 106 +      
ENSG00000178234 E012 0.0000000       7 152074986 152075009 24 +      
ENSG00000178234 E013 0.2842848 0.0288101402 0.8691679379   7 152075010 152075180 171 + 0.132 0.108 -0.327
ENSG00000178234 E014 0.0000000       7 152079275 152079286 12 +      
ENSG00000178234 E015 10.8295564 0.0570239541 0.2242983528 0.62920822 7 152079287 152079408 122 + 0.941 1.122 0.663
ENSG00000178234 E016 1.8263264 0.0099426141 0.0007391188 0.04575220 7 152093966 152093990 25 + 0.000 0.614 12.745
ENSG00000178234 E017 3.4723906 0.0067156899 0.0038519600 0.11104302 7 152093991 152094083 93 + 0.315 0.784 2.253
ENSG00000178234 E018 3.9334460 0.0088282799 0.0194348429 0.23288328 7 152094084 152094189 106 + 0.444 0.804 1.594
ENSG00000178234 E019 86.9666720 0.0005974163 0.0338421190 0.29347248 7 152094190 152094319 130 + 1.981 1.902 -0.265
ENSG00000178234 E020 134.5395792 0.0027503852 0.8696427465 0.96804239 7 152094320 152094522 203 + 2.127 2.121 -0.022
ENSG00000178234 E021 55.1426509 0.0005167278 0.5232708894 0.84173692 7 152100798 152100824 27 + 1.757 1.729 -0.096
ENSG00000178234 E022 94.9487722 0.0003638131 0.6521028345 0.89737673 7 152100825 152100921 97 + 1.967 1.985 0.059
ENSG00000178234 E023 106.8452752 0.0004011080 0.3276754887 0.72283826 7 152103112 152103278 167 + 2.008 2.044 0.119
ENSG00000178234 E024 11.1508056 0.1876965822 0.9378509054 0.98544339 7 152103279 152104892 1614 + 1.075 1.091 0.057
ENSG00000178234 E025 99.3363892 0.0026533428 0.8643896178 0.96696158 7 152105245 152105370 126 + 2.001 1.996 -0.017
ENSG00000178234 E026 0.2842848 0.0288101402 0.8691679379   7 152107250 152108037 788 + 0.132 0.108 -0.327
ENSG00000178234 E027 39.9321838 0.0008174172 0.2295194127 0.63458650 7 152108038 152108040 3 + 1.644 1.580 -0.217
ENSG00000178234 E028 155.0104436 0.0002403326 0.8584617967 0.96527075 7 152108041 152108287 247 + 2.190 2.187 -0.010
ENSG00000178234 E029 138.6786885 0.0002519348 0.9039030675 0.97723922 7 152110528 152110645 118 + 2.142 2.140 -0.006
ENSG00000178234 E030 0.1812101 0.0415337058 0.3916230761   7 152113245 152113245 1 + 0.132 0.000 -10.120
ENSG00000178234 E031 164.4405625 0.0002096149 0.2245361348 0.62940819 7 152113246 152113398 153 + 2.192 2.227 0.116
ENSG00000178234 E032 3.6479995 0.0468007852 0.0203475026 0.23776816 7 152116904 152117038 135 + 0.384 0.786 1.847
ENSG00000178234 E033 192.1993638 0.0001932500 0.1497677928 0.53912046 7 152117157 152117375 219 + 2.257 2.294 0.125
ENSG00000178234 E034 1.5508551 0.2232038769 0.3129186333   7 152117376 152118677 1302 + 0.238 0.476 1.444
ENSG00000178234 E035 122.4478710 0.0002886457 0.1110798573 0.47749441 7 152118678 152118782 105 + 2.056 2.108 0.174
ENSG00000178234 E036 3.8791968 0.0058316717 0.1376974951 0.52173856 7 152118783 152119710 928 + 0.543 0.764 0.949
ENSG00000178234 E037 166.8695156 0.0002224534 0.1158240601 0.48590099 7 152120831 152120968 138 + 2.194 2.238 0.147
ENSG00000178234 E038 397.8647396 0.0049383483 0.9713331457 0.99327255 7 152121546 152122493 948 + 2.595 2.592 -0.008