• ENSG00000172663
  • Isoform Switch

ENSG00000172663

Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000393877 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding protein_coding 50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 4.411741 2.299345 7.078173 0.6072088 2.133459 1.6179300 0.08656250 0.05606667 0.08656667 0.030500000 5.082827e-01 6.209243e-35 FALSE  
ENST00000535175 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding retained_intron 50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 3.063418 4.553070 2.914867 0.4117346 1.059962 -0.6416337 0.07573750 0.11473333 0.04826667 -0.066466667 2.890933e-01 6.209243e-35    
ENST00000537601 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding processed_transcript 50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 0.995014 2.791396 0.000000 0.4051013 0.000000 -8.1300023 0.02826667 0.06760000 0.00000000 -0.067600000 6.209243e-35 6.209243e-35 FALSE  
ENST00000545682 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding nonsense_mediated_decay 50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 5.281868 3.370166 10.378821 0.3527509 2.317986 1.6198661 0.09622083 0.08236667 0.13256667 0.050200000 2.098112e-03 6.209243e-35 TRUE  
MSTRG.5827.5 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding   50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 17.013541 11.784792 27.978298 1.9196707 6.722528 1.2466738 0.32378333 0.28653333 0.35383333 0.067300000 4.597640e-01 6.209243e-35 FALSE  
MSTRG.5827.6 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding   50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 4.433906 2.251417 5.831811 0.8910862 3.610428 1.3691885 0.07392917 0.05150000 0.05986667 0.008366667 9.395385e-01 6.209243e-35 TRUE  
MSTRG.5827.7 ENSG00000172663 HEK293_DMSO_6hA HEK293_OSMI2_6hA TMEM134 protein_coding   50.9336 41.10452 78.04057 4.937801 17.1212 0.9247611 8.280272 5.124965 14.205033 1.0881630 2.611869 1.4689912 0.14794583 0.12263333 0.18653333 0.063900000 1.581599e-01 6.209243e-35 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.