ENSG00000169660

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-8 / 8
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000337014	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding	protein_coding	20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	4.5061312	6.513044	7.052525	0.75746049	0.22858009	0.11463883	0.21394167	0.22486667	0.2455333	0.020666667	7.779970e-01	1.342807e-14	FALSE	TRUE
ENST00000581482	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding	nonsense_mediated_decay	20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	0.5323073	1.791094	0.000000	0.30784692	0.00000000	-7.49273004	0.03325833	0.06160000	0.0000000	-0.061600000	1.342807e-14	1.342807e-14	FALSE	FALSE
ENST00000583978	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding	retained_intron	20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	3.3994518	2.814468	3.612086	0.31131426	0.52671916	0.35884148	0.18894167	0.09683333	0.1257667	0.028933333	7.302989e-01	1.342807e-14		FALSE
ENST00000585077	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding	retained_intron	20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	1.4470536	4.180556	1.852513	0.92628076	1.12411677	-1.16989134	0.07899583	0.14383333	0.0656000	-0.078233333	7.438047e-01	1.342807e-14	FALSE	TRUE
ENST00000644009	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding	protein_coding	20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	3.1236233	2.493365	5.840914	1.12354335	2.00461370	1.22479324	0.11083333	0.08593333	0.2037000	0.117766667	5.018812e-01	1.342807e-14	FALSE	TRUE
ENST00000644886	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding	retained_intron	20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	2.4051815	4.795088	3.258526	0.49088176	0.90589367	-0.55592282	0.13043750	0.16530000	0.1133667	-0.051933333	5.939637e-01	1.342807e-14	FALSE	TRUE
MSTRG.15351.14	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding		20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	1.2136011	2.028067	2.128209	0.49448068	1.07979970	0.06920134	0.06177500	0.06976667	0.0734000	0.003633333	8.809326e-01	1.342807e-14	TRUE	TRUE
MSTRG.15351.23	ENSG00000169660	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	HEXD	protein_coding		20.39204	29.02606	28.70815	0.2493279	0.5618042	-0.01588284	1.1881383	2.544214	1.420552	0.07865831	0.09419748	-0.83630719	0.05751250	0.08760000	0.0494000	-0.038200000	1.035429e-01	1.342807e-14	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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HEK293_OSMI2_6hA
HEK293_DMSO_6hA
log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_OSMI2_6hA	HEK293_DMSO_6hA	log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA

ENSG00000169660	E001	0.000000				17	82418318	82418346	29	+
ENSG00000169660	E002	43.133023	0.0066027321	2.578630e-02	0.261375428	17	82418347	82418660	314	+	1.701	1.576	-0.424
ENSG00000169660	E003	9.988771	0.0510393041	4.772907e-01	0.817937633	17	82418661	82418672	12	+	1.071	1.010	-0.223
ENSG00000169660	E004	11.359722	0.0382167599	9.725606e-02	0.452384683	17	82418673	82418686	14	+	1.182	0.995	-0.677
ENSG00000169660	E005	10.969929	0.0185254290	1.488419e-01	0.537633428	17	82418687	82418689	3	+	1.154	1.007	-0.531
ENSG00000169660	E006	13.235476	0.0205342435	6.851716e-01	0.909995179	17	82418690	82418696	7	+	1.171	1.145	-0.092
ENSG00000169660	E007	14.851238	0.0156625296	4.404244e-01	0.798022345	17	82418697	82418712	16	+	1.233	1.174	-0.211
ENSG00000169660	E008	15.379350	0.0119177683	4.770626e-01	0.817808813	17	82418713	82418715	3	+	1.242	1.192	-0.178
ENSG00000169660	E009	20.593955	0.0038198005	3.344455e-01	0.727923756	17	82418716	82418740	25	+	1.366	1.307	-0.205
ENSG00000169660	E010	45.709921	0.0012877942	4.302935e-02	0.323700542	17	82419749	82419799	51	+	1.715	1.624	-0.308
ENSG00000169660	E011	109.010211	0.0066316766	2.006484e-01	0.604136314	17	82419800	82419883	84	+	2.062	2.018	-0.147
ENSG00000169660	E012	51.634879	0.0270356728	4.326881e-01	0.793294253	17	82419884	82420296	413	+	1.748	1.694	-0.182
ENSG00000169660	E013	31.908149	0.0127763275	5.270732e-01	0.843464671	17	82420297	82420496	200	+	1.528	1.497	-0.108
ENSG00000169660	E014	8.089498	0.0099609603	1.450629e-01	0.532342506	17	82423310	82423599	290	+	0.848	1.033	0.692
ENSG00000169660	E015	74.630135	0.0150336440	6.382175e-01	0.891432454	17	82424394	82424418	25	+	1.878	1.869	-0.031
ENSG00000169660	E016	138.573391	0.0037467392	5.092153e-01	0.834349876	17	82424419	82424503	85	+	2.143	2.135	-0.028
ENSG00000169660	E017	3.540663	0.0136112219	2.530211e-01	0.658822288	17	82428030	82428127	98	+	0.550	0.734	0.794
ENSG00000169660	E018	164.794840	0.0001968188	4.794432e-01	0.818841013	17	82428558	82428645	88	+	2.217	2.214	-0.010
ENSG00000169660	E019	190.313673	0.0003158906	9.425872e-01	0.986566745	17	82433658	82433799	142	+	2.268	2.286	0.061
ENSG00000169660	E020	105.633624	0.0008116045	3.280658e-01	0.723080131	17	82433800	82433822	23	+	2.033	2.015	-0.062
ENSG00000169660	E021	219.117849	0.0019434973	2.109624e-01	0.615258429	17	82435689	82435872	184	+	2.349	2.329	-0.066
ENSG00000169660	E022	129.963626	0.0050495150	1.298214e-02	0.196109349	17	82436667	82436728	62	+	2.159	2.066	-0.310
ENSG00000169660	E023	81.593656	0.0046303242	6.121565e-02	0.374703923	17	82436729	82436738	10	+	1.950	1.874	-0.255
ENSG00000169660	E024	78.745781	0.0435002300	6.216144e-02	0.377406509	17	82436739	82437126	388	+	1.799	1.973	0.587
ENSG00000169660	E025	32.759578	0.0270779986	9.425671e-02	0.446679123	17	82437127	82437167	41	+	1.429	1.594	0.565
ENSG00000169660	E026	122.731102	0.0003084944	7.362890e-06	0.002472398	17	82437168	82437214	47	+	2.148	2.021	-0.424
ENSG00000169660	E027	187.518311	0.0024813253	5.903452e-03	0.136699894	17	82437215	82437363	149	+	2.311	2.236	-0.249
ENSG00000169660	E028	142.153397	0.0015851263	1.256354e-01	0.503462359	17	82439631	82439713	83	+	2.170	2.135	-0.117
ENSG00000169660	E029	86.436892	0.0969586780	1.498841e-01	0.539360294	17	82439714	82439999	286	+	1.858	2.002	0.482
ENSG00000169660	E030	63.485023	0.0994110764	1.335781e-01	0.515595565	17	82440000	82440113	114	+	1.707	1.881	0.589
ENSG00000169660	E031	52.104961	0.1305545876	2.558576e-01	0.661573948	17	82440114	82440173	60	+	1.659	1.774	0.388
ENSG00000169660	E032	50.016565	0.0693106577	9.513743e-02	0.448438527	17	82440174	82440262	89	+	1.592	1.788	0.664
ENSG00000169660	E033	44.269624	0.0466696473	6.807088e-02	0.391436343	17	82440263	82440334	72	+	1.541	1.732	0.653
ENSG00000169660	E034	53.504853	0.0354672164	4.520629e-02	0.330528085	17	82440335	82440472	138	+	1.627	1.809	0.615
ENSG00000169660	E035	67.625492	0.0203154030	1.704551e-02	0.220862355	17	82440473	82440613	141	+	1.722	1.909	0.631
ENSG00000169660	E036	176.221892	0.0006150580	6.927096e-01	0.912693439	17	82440997	82441070	74	+	2.243	2.247	0.015
ENSG00000169660	E037	105.349431	0.0004144038	2.762292e-01	0.679961728	17	82441071	82441075	5	+	1.992	2.045	0.179
ENSG00000169660	E038	91.993622	0.0033346247	6.137875e-03	0.138980156	17	82441076	82441152	77	+	1.885	2.024	0.467
ENSG00000169660	E039	61.728824	0.0116846796	8.502121e-02	0.428074253	17	82441153	82441164	12	+	1.716	1.855	0.469
ENSG00000169660	E040	203.931382	0.0002427844	2.825603e-01	0.685473604	17	82441165	82441266	102	+	2.284	2.327	0.142
ENSG00000169660	E041	25.633686	0.0067267061	3.907235e-03	0.111794347	17	82441744	82441799	56	+	1.282	1.521	0.826
ENSG00000169660	E042	118.721788	0.0003872616	8.471681e-01	0.962188762	17	82441800	82441820	21	+	2.067	2.076	0.032
ENSG00000169660	E043	180.236960	0.0003240879	5.777433e-01	0.865805142	17	82441821	82441889	69	+	2.252	2.253	0.005
ENSG00000169660	E044	300.077556	0.0055443688	8.457150e-01	0.961784575	17	82442177	82442645	469	+	2.468	2.484	0.054

Isoforom Switch Analysis

WANG Ziyi

Date: 18 5月 2022

ENSG00000169660

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3