ENSG00000165119

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000351839 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding protein_coding 611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 72.74896 4.958913 14.255357 2.481555 8.500762 1.5215136 0.10880417 0.01866667 0.02686667 0.00820000 9.834137e-01 7.571065e-88 FALSE TRUE
ENST00000360384 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding protein_coding 611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 81.52137 35.815285 68.612998 6.947863 19.305749 0.9377140 0.13423750 0.11410000 0.16706667 0.05296667 1.004675e-06 7.571065e-88 FALSE TRUE
ENST00000376281 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding protein_coding 611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 40.31980 10.889223 20.787138 2.210124 7.463977 0.9321598 0.06291667 0.03563333 0.04713333 0.01150000 6.718620e-01 7.571065e-88 FALSE TRUE
MSTRG.32917.11 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding   611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 19.63190 37.940941 2.135425 6.393964 2.135425 -4.1448000 0.04245000 0.12176667 0.01120000 -0.11056667 2.052414e-01 7.571065e-88 FALSE TRUE
MSTRG.32917.13 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding   611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 81.66799 0.000000 47.987586 0.000000 18.526671 12.2287461 0.11522083 0.00000000 0.10616667 0.10616667 1.286750e-69 7.571065e-88 FALSE TRUE
MSTRG.32917.14 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding   611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 90.60344 19.946978 70.481965 4.459462 16.578222 1.8205655 0.13794583 0.06443333 0.17843333 0.11400000 1.099990e-07 7.571065e-88 FALSE TRUE
MSTRG.32917.5 ENSG00000165119 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPK protein_coding   611.2141 315.6015 408.1148 61.91603 112.2336 0.3708609 157.73387 149.075903 124.897283 28.879137 34.972618 -0.2552862 0.28487083 0.47246667 0.30603333 -0.16643333 8.139305e-14 7.571065e-88 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000165119 E001 53.56080 9.710242e-03 7.339514e-02 4.030300e-01 9 83968083 83968196 114 - 1.802 1.664 -0.468
ENSG00000165119 E002 1127.03517 4.950772e-03 3.151179e-01 7.124051e-01 9 83968197 83968908 712 - 3.071 3.032 -0.128
ENSG00000165119 E003 2277.45149 5.615709e-05 1.033683e-12 8.156697e-09 9 83968909 83969197 289 - 3.330 3.387 0.187
ENSG00000165119 E004 2848.87228 8.263011e-04 2.448156e-03 8.863480e-02 9 83969198 83969380 183 - 3.434 3.476 0.140
ENSG00000165119 E005 978.34710 4.914116e-03 3.722739e-01 7.548780e-01 9 83969381 83969415 35 - 2.981 3.001 0.065
ENSG00000165119 E006 862.06880 4.707471e-03 3.240234e-01 7.201150e-01 9 83969416 83969440 25 - 2.924 2.948 0.078
ENSG00000165119 E007 21.91871 1.105147e-01 4.532224e-02 3.310108e-01 9 83969496 83969747 252 - 1.146 1.504 1.250
ENSG00000165119 E008 26.96449 1.110498e-01 1.169814e-02 1.870044e-01 9 83969748 83970161 414 - 1.166 1.621 1.580
ENSG00000165119 E009 3604.98530 1.899588e-04 6.599038e-02 3.867205e-01 9 83970162 83970312 151 - 3.550 3.565 0.050
ENSG00000165119 E010 2106.95006 3.739376e-04 1.351592e-01 5.181154e-01 9 83970313 83970331 19 - 3.314 3.333 0.064
ENSG00000165119 E011 27.26380 1.218451e-01 2.033262e-02 2.376427e-01 9 83970332 83970736 405 - 1.166 1.630 1.611
ENSG00000165119 E012 2833.76515 4.022064e-04 8.035952e-01 9.494143e-01 9 83970737 83970819 83 - 3.449 3.455 0.020
ENSG00000165119 E013 1680.21543 6.514412e-04 3.340031e-01 7.276333e-01 9 83970897 83970912 16 - 3.230 3.220 -0.034
ENSG00000165119 E014 288.05936 9.812358e-04 5.773255e-01 8.655367e-01 9 83970913 83971146 234 - 2.457 2.471 0.049
ENSG00000165119 E015 2532.13110 8.736179e-04 6.413035e-02 3.819488e-01 9 83971273 83971356 84 - 3.415 3.391 -0.078
ENSG00000165119 E016 2165.97386 5.339122e-04 1.579584e-01 5.511947e-01 9 83971672 83971726 55 - 3.343 3.327 -0.052
ENSG00000165119 E017 4630.28501 3.949806e-05 8.195227e-01 9.543897e-01 9 83971882 83972189 308 - 3.667 3.666 -0.005
ENSG00000165119 E018 3002.61302 4.226148e-05 2.417563e-01 6.467956e-01 9 83972844 83972972 129 - 3.476 3.483 0.024
ENSG00000165119 E019 1511.27083 1.111360e-04 2.604812e-01 6.659030e-01 9 83973286 83973291 6 - 3.176 3.187 0.035
ENSG00000165119 E020 2794.33807 8.346850e-05 4.390447e-01 7.971013e-01 9 83973292 83973399 108 - 3.445 3.450 0.016
ENSG00000165119 E021 1911.74196 4.865122e-05 9.139677e-01 9.794206e-01 9 83973902 83973973 72 - 3.284 3.282 -0.006
ENSG00000165119 E022 2096.69325 2.391614e-04 3.633711e-02 3.017417e-01 9 83974517 83974589 73 - 3.334 3.311 -0.079
ENSG00000165119 E023 1852.27200 4.909848e-04 1.324829e-01 5.141051e-01 9 83975462 83975505 44 - 3.279 3.258 -0.069
ENSG00000165119 E024 28.03037 2.108997e-01 1.662535e-01 5.622402e-01 9 83975506 83975770 265 - 1.271 1.602 1.145
ENSG00000165119 E025 31.44308 1.164455e-01 4.060520e-02 3.162107e-01 9 83976508 83976994 487 - 1.287 1.664 1.297
ENSG00000165119 E026 2148.08729 6.195514e-04 5.298695e-01 8.448637e-01 9 83976995 83977051 57 - 3.336 3.330 -0.023
ENSG00000165119 E027 2763.88906 3.133998e-04 1.409907e-01 5.266421e-01 9 83977689 83977786 98 - 3.448 3.436 -0.042
ENSG00000165119 E028 2418.73647 9.864530e-05 2.274592e-02 2.489402e-01 9 83978195 83978279 85 - 3.394 3.375 -0.062
ENSG00000165119 E029 1709.11635 1.323320e-04 2.672109e-05 5.864802e-03 9 83978373 83978452 80 - 3.255 3.213 -0.140
ENSG00000165119 E030 18.86544 5.193428e-02 8.741896e-01 9.695857e-01 9 83979601 83979659 59 - 1.293 1.309 0.054
ENSG00000165119 E031 120.19757 4.682971e-03 4.758656e-03 1.239083e-01 9 83980119 83980152 34 - 2.148 2.013 -0.456
ENSG00000165119 E032 503.72854 1.481006e-03 4.662060e-10 1.589473e-06 9 83980153 83980502 350 - 2.775 2.615 -0.532
ENSG00000165119 E033 514.92797 1.725597e-04 8.280603e-02 4.236133e-01 9 83980503 83980696 194 - 2.701 2.729 0.095