ENSG00000165097

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000449850 ENSG00000165097 HEK293_DMSO_6hA HEK293_OSMI2_6hA KDM1B protein_coding protein_coding 10.44141 3.407786 5.304234 0.7813844 1.366732 0.6367999 0.8938271 0.2624656 0.1756982 0.1992020 0.03439207 -0.5531146 0.07823750 0.08906667 0.03483333 -0.05423333 1.000000e+00 1.214661e-23 FALSE TRUE
ENST00000546309 ENSG00000165097 HEK293_DMSO_6hA HEK293_OSMI2_6hA KDM1B protein_coding protein_coding 10.44141 3.407786 5.304234 0.7813844 1.366732 0.6367999 0.2993390 0.0000000 0.2712900 0.0000000 0.27128997 4.8139862 0.05656250 0.00000000 0.03920000 0.03920000 7.700337e-01 1.214661e-23 FALSE TRUE
ENST00000650836 ENSG00000165097 HEK293_DMSO_6hA HEK293_OSMI2_6hA KDM1B protein_coding protein_coding 10.44141 3.407786 5.304234 0.7813844 1.366732 0.6367999 5.5775935 0.0000000 3.1151661 0.0000000 0.85933194 8.2877891 0.44057917 0.00000000 0.58406667 0.58406667 1.214661e-23 1.214661e-23 FALSE TRUE
MSTRG.27699.2 ENSG00000165097 HEK293_DMSO_6hA HEK293_OSMI2_6hA KDM1B protein_coding   10.44141 3.407786 5.304234 0.7813844 1.366732 0.6367999 1.1680794 0.0000000 0.3550926 0.0000000 0.35509262 5.1901906 0.08812917 0.00000000 0.05540000 0.05540000 7.568901e-01 1.214661e-23 FALSE TRUE
MSTRG.27699.5 ENSG00000165097 HEK293_DMSO_6hA HEK293_OSMI2_6hA KDM1B protein_coding   10.44141 3.407786 5.304234 0.7813844 1.366732 0.6367999 1.0382375 1.1257588 0.9699761 0.4409226 0.64946790 -0.2128380 0.13320417 0.30860000 0.19723333 -0.11136667 7.503656e-01 1.214661e-23 FALSE TRUE
MSTRG.27699.7 ENSG00000165097 HEK293_DMSO_6hA HEK293_OSMI2_6hA KDM1B protein_coding   10.44141 3.407786 5.304234 0.7813844 1.366732 0.6367999 0.8168206 1.5497529 0.1626024 0.3223485 0.16260237 -3.1757933 0.13805000 0.46840000 0.02536667 -0.44303333 9.618482e-03 1.214661e-23 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000165097 E001 0.0000000       6 18155329 18155404 76 +      
ENSG00000165097 E002 0.0000000       6 18155405 18155413 9 +      
ENSG00000165097 E003 0.0000000       6 18155414 18155421 8 +      
ENSG00000165097 E004 0.2937266 0.0274424043 0.3283626314   6 18155422 18155443 22 + 0.183 0.000 -9.424
ENSG00000165097 E005 0.2937266 0.0274424043 0.3283626314   6 18155444 18155451 8 + 0.183 0.000 -11.898
ENSG00000165097 E006 5.0486459 0.0048443620 0.0002042119 0.02068522 6 18155452 18155571 120 + 0.958 0.404 -2.393
ENSG00000165097 E007 8.6079758 0.0059391503 0.0386777468 0.30964314 6 18155883 18155926 44 + 1.068 0.830 -0.892
ENSG00000165097 E008 0.2250332 0.0513514683 0.3412398431   6 18156278 18156377 100 + 0.181 0.000 -11.715
ENSG00000165097 E009 21.4287110 0.0297858468 0.2916969290 0.69281173 6 18159883 18159982 100 + 1.390 1.295 -0.331
ENSG00000165097 E010 33.3991434 0.0176729182 0.7226648129 0.92304396 6 18161327 18161454 128 + 1.547 1.530 -0.058
ENSG00000165097 E011 25.2447500 0.0015516506 0.4685997952 0.81326822 6 18162835 18162924 90 + 1.407 1.457 0.175
ENSG00000165097 E012 32.2536096 0.0009444855 0.9252618752 0.98226819 6 18166267 18166378 112 + 1.520 1.527 0.024
ENSG00000165097 E013 35.7803839 0.0013022093 0.7854142216 0.94372352 6 18171363 18171479 117 + 1.572 1.556 -0.053
ENSG00000165097 E014 15.9038253 0.0195084149 0.9102446443 0.97856319 6 18185772 18185810 39 + 1.234 1.215 -0.066
ENSG00000165097 E015 26.0885632 0.0029035080 0.1197926266 0.49314874 6 18187792 18188002 211 + 1.486 1.374 -0.385
ENSG00000165097 E016 28.9735263 0.0187640500 0.2962714265 0.69669907 6 18191197 18191381 185 + 1.524 1.421 -0.352
ENSG00000165097 E017 45.7234367 0.0007412760 0.3166011954 0.71374284 6 18197057 18197233 177 + 1.697 1.648 -0.168
ENSG00000165097 E018 28.3734326 0.0011824751 0.9678217045 0.99256772 6 18197587 18197661 75 + 1.469 1.469 -0.002
ENSG00000165097 E019 40.0658157 0.0008752682 0.9344870044 0.98464682 6 18200439 18200576 138 + 1.610 1.616 0.023
ENSG00000165097 E020 44.4270520 0.0007710117 0.4659887502 0.81182813 6 18201486 18201657 172 + 1.642 1.680 0.131
ENSG00000165097 E021 42.7132939 0.0009773662 0.8330584127 0.95792266 6 18205537 18205664 128 + 1.644 1.655 0.039
ENSG00000165097 E022 40.2374800 0.0006792294 0.5993134942 0.87525526 6 18207398 18207529 132 + 1.607 1.636 0.101
ENSG00000165097 E023 0.9841036 0.0156845648 0.6474725014   6 18208129 18208131 3 + 0.252 0.333 0.556
ENSG00000165097 E024 24.1306149 0.0034533287 0.3566500605 0.74446533 6 18208132 18208206 75 + 1.361 1.433 0.249
ENSG00000165097 E025 7.7547508 0.1555034930 0.0433622049 0.32461758 6 18211495 18212487 993 + 0.704 1.123 1.597
ENSG00000165097 E026 35.0224769 0.0081397213 0.2703576378 0.67466860 6 18212488 18212604 117 + 1.513 1.606 0.318
ENSG00000165097 E027 32.8920071 0.0010927566 0.3485713698 0.73833486 6 18213656 18213781 126 + 1.506 1.565 0.201
ENSG00000165097 E028 30.3535547 0.0012049865 0.5002269802 0.82976437 6 18215007 18215129 123 + 1.516 1.475 -0.143
ENSG00000165097 E029 38.7587288 0.0009102406 0.9931006435 0.99833918 6 18217733 18217880 148 + 1.609 1.608 -0.001
ENSG00000165097 E030 20.2731952 0.0015033261 0.8907151489 0.97383497 6 18217881 18217885 5 + 1.334 1.345 0.037
ENSG00000165097 E031 237.2048229 0.0059406565 0.5380732380 0.84888589 6 18221909 18223854 1946 + 2.367 2.386 0.066