ENSG00000155893

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000286353 ENSG00000155893 HEK293_DMSO_6hA HEK293_OSMI2_6hA PXYLP1 protein_coding protein_coding 6.414944 3.57684 5.196168 0.5902784 0.8198009 0.5375086 3.4575699 1.8238988 2.35583970 0.7481129 0.34472516 0.3674383 0.53222083 0.4808000 0.470966667 -0.009833333 1.00000000 0.01606031 FALSE TRUE
ENST00000502783 ENSG00000155893 HEK293_DMSO_6hA HEK293_OSMI2_6hA PXYLP1 protein_coding protein_coding 6.414944 3.57684 5.196168 0.5902784 0.8198009 0.5375086 0.8086484 0.0000000 0.57619357 0.0000000 0.37182785 5.8733052 0.10562500 0.0000000 0.102366667 0.102366667 0.01606031 0.01606031 FALSE TRUE
ENST00000504264 ENSG00000155893 HEK293_DMSO_6hA HEK293_OSMI2_6hA PXYLP1 protein_coding protein_coding 6.414944 3.57684 5.196168 0.5902784 0.8198009 0.5375086 0.1858058 0.3064280 0.05198398 0.3064280 0.05198398 -2.3519100 0.03671667 0.1002000 0.008266667 -0.091933333 0.97978361 0.01606031 FALSE TRUE
ENST00000505502 ENSG00000155893 HEK293_DMSO_6hA HEK293_OSMI2_6hA PXYLP1 protein_coding processed_transcript 6.414944 3.57684 5.196168 0.5902784 0.8198009 0.5375086 1.0513515 0.6196768 1.56851112 0.1785606 0.41744979 1.3258809 0.17712917 0.1941333 0.289633333 0.095500000 0.72399747 0.01606031   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000155893 E001 0.0000000       3 141228726 141228803 78 +      
ENSG00000155893 E002 0.5830138 0.0193118314 7.252619e-02   3 141231784 141231824 41 + 0.319 0.000 -10.550
ENSG00000155893 E003 0.7597844 0.0172111373 3.773889e-02   3 141231825 141231828 4 + 0.372 0.000 -12.880
ENSG00000155893 E004 1.0938179 0.0139082065 4.480707e-01   3 141231829 141231839 11 + 0.372 0.241 -0.875
ENSG00000155893 E005 3.6689860 0.0139254943 1.133209e-01 0.48149595 3 141231840 141231860 21 + 0.750 0.508 -1.059
ENSG00000155893 E006 3.8940192 0.0063088151 5.672817e-02 0.36303694 3 141231861 141231866 6 + 0.789 0.508 -1.215
ENSG00000155893 E007 4.4237680 0.0054835648 5.651797e-02 0.36242933 3 141231867 141231875 9 + 0.826 0.555 -1.138
ENSG00000155893 E008 4.4237680 0.0054835648 5.651797e-02 0.36242933 3 141231876 141231878 3 + 0.826 0.555 -1.138
ENSG00000155893 E009 4.4237680 0.0054835648 5.651797e-02 0.36242933 3 141231879 141231881 3 + 0.826 0.555 -1.138
ENSG00000155893 E010 6.1078414 0.0072510994 3.363955e-02 0.29284873 3 141231882 141231911 30 + 0.948 0.672 -1.089
ENSG00000155893 E011 0.1544607 0.0315862126 3.704343e-01   3 141231914 141231980 67 + 0.000 0.137 10.261
ENSG00000155893 E012 0.9495495 0.0149376927 2.423028e-01   3 141232333 141232435 103 + 0.188 0.394 1.448
ENSG00000155893 E013 5.4726370 0.0325298628 2.908806e-01 0.69222267 3 141234216 141234318 103 + 0.863 0.706 -0.628
ENSG00000155893 E014 6.6277286 0.1492118529 1.556059e-01 0.54743953 3 141234886 141234956 71 + 0.988 0.675 -1.223
ENSG00000155893 E015 1.7964999 0.0120350531 4.301281e-01 0.79192469 3 141234957 141235397 441 + 0.372 0.508 0.711
ENSG00000155893 E016 8.9489829 0.0627522130 3.647194e-01 0.75012183 3 141235398 141235554 157 + 1.053 0.908 -0.542
ENSG00000155893 E017 4.5230657 0.1168673044 1.411753e-01 0.52692783 3 141236272 141236389 118 + 0.854 0.556 -1.240
ENSG00000155893 E018 10.5608592 0.0111554412 2.024660e-01 0.60621812 3 141260123 141260254 132 + 1.134 0.995 -0.506
ENSG00000155893 E019 1.0432724 0.3121435171 9.492646e-01   3 141261866 141262005 140 + 0.350 0.322 -0.176
ENSG00000155893 E020 0.7762952 0.2156282612 8.451081e-01   3 141262006 141262049 44 + 0.306 0.240 -0.472
ENSG00000155893 E021 2.7283016 0.2276658492 1.765611e-01 0.57480856 3 141262243 141262340 98 + 0.732 0.325 -1.983
ENSG00000155893 E022 0.6378259 0.0301827882 4.773658e-01   3 141262341 141262613 273 + 0.259 0.137 -1.139
ENSG00000155893 E023 0.5735719 0.0198552846 4.776543e-01   3 141262614 141262723 110 + 0.258 0.137 -1.134
ENSG00000155893 E024 16.0567400 0.0837249530 4.579316e-02 0.33222444 3 141272665 141274623 1959 + 1.071 1.367 1.050
ENSG00000155893 E025 22.1503769 0.0012948240 3.728682e-01 0.75525624 3 141278342 141278500 159 + 1.395 1.337 -0.203
ENSG00000155893 E026 22.0956740 0.0013968241 1.135991e-01 0.48182826 3 141279378 141279504 127 + 1.414 1.306 -0.375
ENSG00000155893 E027 18.0090522 0.0203535866 9.178477e-01 0.98030932 3 141287314 141287358 45 + 1.275 1.279 0.015
ENSG00000155893 E028 23.6849509 0.0200789211 7.493157e-01 0.93242650 3 141287359 141287453 95 + 1.399 1.383 -0.056
ENSG00000155893 E029 0.8190360 0.0178208141 2.925069e-01   3 141287454 141287454 1 + 0.320 0.137 -1.555
ENSG00000155893 E030 1.7462756 0.0101448899 4.365298e-01 0.79552614 3 141291588 141291732 145 + 0.372 0.508 0.710
ENSG00000155893 E031 242.1223669 0.0009717018 6.949743e-05 0.01095752 3 141292268 141294924 2657 + 2.355 2.424 0.231
ENSG00000155893 E032 0.6010108 0.0191750579 1.957629e-01   3 141305756 141307776 2021 + 0.104 0.324 2.034
ENSG00000155893 E033 0.0000000       3 141308204 141308407 204 +      
ENSG00000155893 E034 0.0000000       3 141311637 141311756 120 +      
ENSG00000155893 E035 2.1765025 0.0094249914 2.106376e-03 0.08185126 3 141316255 141317922 1668 + 0.188 0.705 2.905
ENSG00000155893 E036 1.8789893 0.0122480853 2.919452e-01 0.69292495 3 141321012 141321722 711 + 0.372 0.555 0.931
ENSG00000155893 E037 0.0000000       3 141366246 141367753 1508 +