ENSG00000147162

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373701 ENSG00000147162 HEK293_DMSO_6hA HEK293_OSMI2_6hA OGT protein_coding protein_coding 30.39283 38.3439 11.82128 11.37478 2.890181 -1.696767 1.045033 2.095710 1.0551792 0.6386295 1.05517916 -0.9832109 0.05921667 0.06723333 0.06120000 -0.006033333 0.53124016 0.01604106 FALSE TRUE
ENST00000373719 ENSG00000147162 HEK293_DMSO_6hA HEK293_OSMI2_6hA OGT protein_coding protein_coding 30.39283 38.3439 11.82128 11.37478 2.890181 -1.696767 15.114987 19.995565 9.3120120 6.7174255 2.26865424 -1.1016881 0.53154583 0.50963333 0.78586667 0.276233333 0.08676692 0.01604106 FALSE TRUE
ENST00000459760 ENSG00000147162 HEK293_DMSO_6hA HEK293_OSMI2_6hA OGT protein_coding processed_transcript 30.39283 38.3439 11.82128 11.37478 2.890181 -1.696767 2.540424 0.000000 0.0000000 0.0000000 0.00000000 0.0000000 0.06507917 0.00000000 0.00000000 0.000000000   0.01604106 FALSE FALSE
MSTRG.34438.1 ENSG00000147162 HEK293_DMSO_6hA HEK293_OSMI2_6hA OGT protein_coding   30.39283 38.3439 11.82128 11.37478 2.890181 -1.696767 1.759288 3.848454 0.3820930 0.6154973 0.12487163 -3.2987553 0.05898750 0.10800000 0.03340000 -0.074600000 0.01604106 0.01604106 FALSE TRUE
MSTRG.34438.4 ENSG00000147162 HEK293_DMSO_6hA HEK293_OSMI2_6hA OGT protein_coding   30.39283 38.3439 11.82128 11.37478 2.890181 -1.696767 5.426363 2.408136 0.1562738 2.0299761 0.07894512 -3.8622627 0.14157917 0.04653333 0.01463333 -0.031900000 0.84417310 0.01604106 FALSE TRUE
MSTRG.34438.5 ENSG00000147162 HEK293_DMSO_6hA HEK293_OSMI2_6hA OGT protein_coding   30.39283 38.3439 11.82128 11.37478 2.890181 -1.696767 2.497522 6.594929 0.4098774 0.2759318 0.40987740 -3.9755031 0.08895000 0.20063333 0.05566667 -0.144966667 0.32918381 0.01604106 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000147162 E001 6.2741469 0.0455505321 3.722688e-01 0.7548780192 X 71533096 71533103 8 + 0.866 0.737 -0.512
ENSG00000147162 E002 7.0262532 0.0233286848 3.705802e-01 0.7538403355 X 71533104 71533110 7 + 0.901 0.784 -0.456
ENSG00000147162 E003 17.3099091 0.0057668096 2.191488e-01 0.6237389132 X 71533111 71533122 12 + 1.242 1.141 -0.360
ENSG00000147162 E004 24.5234823 0.0011792140 7.884807e-02 0.4150670962 X 71533123 71533127 5 + 1.399 1.280 -0.413
ENSG00000147162 E005 103.6556564 0.0003511012 5.383554e-04 0.0376414922 X 71533128 71533299 172 + 2.005 1.887 -0.395
ENSG00000147162 E006 77.1918324 0.0004961360 5.041918e-04 0.0362311845 X 71533300 71533336 37 + 1.894 1.753 -0.474
ENSG00000147162 E007 0.1767706 0.0411982473 1.009727e-01   X 71534301 71534373 73 + 0.214 0.000 -18.863
ENSG00000147162 E008 61.6725413 0.0007842667 2.578131e-03 0.0909558374 X 71536178 71536207 30 + 1.796 1.658 -0.464
ENSG00000147162 E009 117.1117109 0.0002781641 4.602714e-07 0.0003231827 X 71536208 71536358 151 + 2.095 1.929 -0.556
ENSG00000147162 E010 1.7337931 0.3044940056 9.868023e-01 0.9967318082 X 71536359 71536657 299 + 0.364 0.359 -0.029
ENSG00000147162 E011 0.5203070 0.5216173642 5.822271e-01   X 71537014 71537110 97 + 0.218 0.120 -1.031
ENSG00000147162 E012 135.4492807 0.0002769349 1.340311e-07 0.0001272472 X 71537829 71538072 244 + 2.155 1.994 -0.539
ENSG00000147162 E013 74.5418268 0.0004525299 1.361883e-03 0.0645831654 X 71544567 71544635 69 + 1.875 1.747 -0.434
ENSG00000147162 E014 318.4671428 0.2619077069 2.213496e-02 0.2461554705 X 71544636 71546210 1575 + 1.929 2.452 1.749
ENSG00000147162 E015 50.9277984 0.3636303589 7.173102e-03 0.1491344762 X 71546211 71546280 70 + 0.934 1.675 2.611
ENSG00000147162 E016 37.0976971 0.1687715598 1.022959e-02 0.1753706103 X 71546281 71546343 63 + 0.992 1.531 1.901
ENSG00000147162 E017 74.0332316 0.4076794393 5.466460e-02 0.3574976251 X 71546344 71546489 146 + 1.380 1.818 1.492
ENSG00000147162 E018 395.6653396 0.1859881362 5.138633e-03 0.1284252720 X 71546490 71547906 1417 + 2.005 2.547 1.811
ENSG00000147162 E019 150.9303535 0.0003481640 6.226865e-01 0.8852349872 X 71547907 71548023 117 + 2.068 2.076 0.025
ENSG00000147162 E020 0.7990528 0.3296789531 8.018523e-01   X 71553621 71553645 25 + 0.217 0.209 -0.066
ENSG00000147162 E021 148.9421027 0.0009732536 9.520154e-01 0.9887842145 X 71554513 71554592 80 + 2.049 2.070 0.070
ENSG00000147162 E022 183.8364225 0.0001790411 3.117150e-02 0.2840315599 X 71555190 71555385 196 + 2.194 2.151 -0.144
ENSG00000147162 E023 1.2831075 0.1790869478 8.081638e-01   X 71555813 71555953 141 + 0.215 0.320 0.768
ENSG00000147162 E024 179.0132005 0.0002017502 9.656685e-01 0.9921009013 X 71555954 71556094 141 + 2.127 2.151 0.081
ENSG00000147162 E025 0.5136063 0.0348328355 6.565417e-01   X 71556456 71556679 224 + 0.000 0.169 16.283
ENSG00000147162 E026 144.4725003 0.0002456690 1.282285e-01 0.5075749970 X 71556680 71556780 101 + 2.077 2.048 -0.099
ENSG00000147162 E027 167.8137941 0.0002349701 7.826587e-01 0.9430053915 X 71556952 71557105 154 + 2.089 2.124 0.118
ENSG00000147162 E028 147.5724920 0.0002262732 9.708780e-02 0.4519953560 X 71557195 71557296 102 + 1.991 2.080 0.299
ENSG00000147162 E029 212.9010864 0.0041144404 8.658436e-01 0.9672440589 X 71557493 71557672 180 + 2.201 2.223 0.072
ENSG00000147162 E030 237.1491381 0.0060669156 9.012178e-01 0.9765729245 X 71559267 71559425 159 + 2.236 2.272 0.121
ENSG00000147162 E031 180.5529576 0.0016295640 4.179152e-01 0.7851975577 X 71559588 71559677 90 + 2.152 2.150 -0.008
ENSG00000147162 E032 177.2028005 0.0003296640 5.837777e-01 0.8684240193 X 71561775 71561900 126 + 2.137 2.145 0.027
ENSG00000147162 E033 254.3560874 0.0014988937 7.228865e-01 0.9231529823 X 71562847 71563017 171 + 2.286 2.301 0.052
ENSG00000147162 E034 272.5823687 0.0002177982 1.153856e-01 0.4852657152 X 71563130 71563246 117 + 2.272 2.342 0.234
ENSG00000147162 E035 349.6841021 0.0001445898 7.550301e-02 0.4080172100 X 71563329 71563499 171 + 2.380 2.448 0.229
ENSG00000147162 E036 227.1839175 0.0001563605 4.319096e-01 0.7930565284 X 71564601 71564663 63 + 2.209 2.258 0.164
ENSG00000147162 E037 269.2688960 0.0001496626 7.800736e-01 0.9422476452 X 71564664 71564753 90 + 2.295 2.328 0.110
ENSG00000147162 E038 408.5001164 0.0011775896 6.213674e-01 0.8845951457 X 71567500 71567752 253 + 2.476 2.506 0.099
ENSG00000147162 E039 2.8231464 0.0074247887 1.220996e-01 0.4973954021 X 71567753 71567973 221 + 0.682 0.438 -1.126
ENSG00000147162 E040 312.9653818 0.0009250385 6.772186e-01 0.9071046688 X 71567993 71568116 124 + 2.380 2.387 0.024
ENSG00000147162 E041 2044.1764681 0.0114060522 3.730775e-02 0.3049343868 X 71573620 71575892 2273 + 3.268 3.181 -0.288