ENSG00000131652

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000326266	ENSG00000131652	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	THOC6	protein_coding	protein_coding	82.85724	74.70361	117.4021	8.660824	20.62019	0.6521379	52.249416	44.224810	89.910774	6.7093933	16.577453	1.0234723	0.62605417	0.58633333	0.76480000	0.17846667	7.309314e-06	7.309314e-06	FALSE	TRUE
ENST00000574957	ENSG00000131652	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	THOC6	protein_coding	retained_intron	82.85724	74.70361	117.4021	8.660824	20.62019	0.6521379	3.346625	5.155761	3.691575	0.2281241	1.101767	-0.4808418	0.05285833	0.07096667	0.03760000	-0.03336667	3.445877e-01	7.309314e-06		FALSE
MSTRG.11906.7	ENSG00000131652	HEK293_DMSO_6hA	HEK293_OSMI2_6hA	THOC6	protein_coding		82.85724	74.70361	117.4021	8.660824	20.62019	0.6521379	17.760724	14.230260	11.539244	1.2456216	5.209014	-0.3021771	0.19548333	0.19253333	0.09026667	-0.10226667	2.535834e-01	7.309314e-06	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
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HEK293_OSMI2_6hA
HEK293_DMSO_6hA
log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_OSMI2_6hA	HEK293_DMSO_6hA	log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA

ENSG00000131652	E001	3.433775	6.283034e-03	0.6408477909	0.89262866	16	3024027	3024030	4	+	0.615	0.687	0.308
ENSG00000131652	E002	3.259205	7.035719e-03	0.8300136044	0.95688932	16	3024031	3024034	4	+	0.642	0.612	-0.130
ENSG00000131652	E003	8.881242	3.173434e-03	0.2405253283	0.64560721	16	3024035	3024040	6	+	1.047	0.921	-0.465
ENSG00000131652	E004	9.925312	4.561138e-03	0.1223698240	0.49784639	16	3024041	3024042	2	+	1.103	0.941	-0.596
ENSG00000131652	E005	22.176219	3.282861e-03	0.0001328306	0.01599653	16	3024043	3024053	11	+	1.477	1.173	-1.060
ENSG00000131652	E006	26.399842	1.391754e-03	0.0003062872	0.02682587	16	3024054	3024059	6	+	1.534	1.282	-0.872
ENSG00000131652	E007	27.898266	1.179728e-03	0.0002354338	0.02258264	16	3024060	3024060	1	+	1.557	1.308	-0.860
ENSG00000131652	E008	32.991785	1.328177e-02	0.0089477221	0.16469156	16	3024061	3024063	3	+	1.617	1.398	-0.750
ENSG00000131652	E009	67.483275	1.691263e-02	0.0958290863	0.44973971	16	3024064	3024086	23	+	1.887	1.757	-0.438
ENSG00000131652	E010	119.094912	1.081348e-02	0.0429667301	0.32357634	16	3024087	3024137	51	+	2.125	2.006	-0.398
ENSG00000131652	E011	297.169334	1.612958e-04	0.2297582002	0.63475103	16	3024138	3024192	55	+	2.481	2.461	-0.068
ENSG00000131652	E012	650.404637	2.232079e-04	0.1618331858	0.55662908	16	3024193	3024365	173	+	2.818	2.803	-0.049
ENSG00000131652	E013	256.200233	2.672497e-04	0.7878410893	0.94450451	16	3025708	3025711	4	+	2.405	2.416	0.036
ENSG00000131652	E014	680.870673	1.620436e-03	0.8187521904	0.95414007	16	3025712	3025823	112	+	2.820	2.842	0.073
ENSG00000131652	E015	31.422318	2.195433e-02	0.0030959521	0.10008854	16	3025824	3025923	100	+	1.353	1.645	1.003
ENSG00000131652	E016	549.378338	2.025473e-03	0.5691696963	0.86202692	16	3025924	3025988	65	+	2.722	2.754	0.107
ENSG00000131652	E017	77.496750	6.110656e-02	0.0261287387	0.26288811	16	3025989	3026062	74	+	1.746	2.026	0.945
ENSG00000131652	E018	734.785423	1.003421e-03	0.7552256056	0.93432738	16	3026063	3026166	104	+	2.854	2.872	0.062
ENSG00000131652	E019	82.881998	8.810501e-02	0.0285848885	0.27396536	16	3026167	3026250	84	+	1.759	2.067	1.036
ENSG00000131652	E020	562.359258	2.447148e-04	0.6037567508	0.87722437	16	3026251	3026288	38	+	2.740	2.755	0.048
ENSG00000131652	E021	61.777726	1.209909e-01	0.0579980862	0.36622773	16	3026289	3026364	76	+	1.641	1.936	0.996
ENSG00000131652	E022	667.607705	6.851427e-04	0.8959809503	0.97510299	16	3026365	3026413	49	+	2.816	2.827	0.037
ENSG00000131652	E023	38.395700	9.423727e-02	0.0544679219	0.35699228	16	3026414	3026515	102	+	1.445	1.728	0.965
ENSG00000131652	E024	830.121425	1.334753e-04	0.2042486112	0.60817928	16	3026516	3026587	72	+	2.907	2.929	0.072
ENSG00000131652	E025	886.840765	3.390076e-04	0.6440054944	0.89394320	16	3026679	3026781	103	+	2.947	2.946	-0.002
ENSG00000131652	E026	716.100590	3.296401e-04	0.3575108119	0.74512683	16	3026867	3026916	50	+	2.857	2.849	-0.026
ENSG00000131652	E027	675.366889	2.806787e-04	0.0197629907	0.23442415	16	3027011	3027073	63	+	2.840	2.811	-0.097
ENSG00000131652	E028	868.473874	9.864519e-05	0.1807294332	0.58027850	16	3027170	3027280	111	+	2.942	2.931	-0.038
ENSG00000131652	E029	766.021703	1.353438e-04	0.6339334247	0.88955529	16	3027366	3027500	135	+	2.877	2.889	0.040
ENSG00000131652	E030	485.350651	2.644238e-04	0.9106410804	0.97861488	16	3027577	3027814	238	+	2.684	2.687	0.013

Isoforom Switch Analysis

WANG Ziyi

Date: 18 5月 2022

ENSG00000131652

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3