ENSG00000092199

Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000553753 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding protein_coding 1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 49.47502 49.07674 22.01698 12.085589 3.593392 -1.1560615 0.05014167 0.05033333 0.04646667 -0.003866667 0.85318124 0.01171624 FALSE TRUE
ENST00000554455 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding protein_coding 1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 174.67803 199.30418 74.88592 33.258151 12.029685 -1.4120854 0.17744583 0.20823333 0.15800000 -0.050233333 0.01171624 0.01171624 FALSE TRUE
ENST00000555914 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding protein_coding 1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 84.63499 82.54262 42.34425 12.709934 8.242522 -0.9628072 0.08400000 0.08656667 0.08860000 0.002033333 0.97088877 0.01171624 FALSE TRUE
ENST00000556897 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding protein_coding 1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 103.01679 112.90370 56.17757 10.255837 6.465300 -1.0068978 0.11069167 0.12046667 0.12096667 0.000500000 1.00000000 0.01171624 FALSE TRUE
ENST00000557157 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding protein_coding 1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 114.95740 110.62110 46.92847 16.171222 15.505863 -1.2369142 0.10227500 0.11620000 0.09476667 -0.021433333 0.62651827 0.01171624 FALSE FALSE
ENST00000557201 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding protein_coding 1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 212.11650 188.22928 107.68071 19.493624 19.327942 -0.8056739 0.20485000 0.20006667 0.22530000 0.025233333 0.35794277 0.01171624 FALSE TRUE
MSTRG.9165.28 ENSG00000092199 HEK293_DMSO_6hA HEK293_OSMI2_6hA HNRNPC protein_coding   1037.607 946.1533 478.4774 116.5338 86.26408 -0.9836081 145.94434 120.91916 78.49031 7.186098 19.210503 -0.6233920 0.13210000 0.13016667 0.15903333 0.028866667 0.50681930 0.01171624 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.