ENSG00000007264

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000310132 ENSG00000007264 HEK293_DMSO_6hA HEK293_OSMI2_6hA MATK protein_coding protein_coding 44.80419 32.19915 67.26458 3.588724 14.93389 1.062591 20.207227 12.600798 31.146373 1.1334230 7.6333510 1.3048677 0.46047500 0.39503333 0.45586667 0.06083333 0.473911715 0.009658657 FALSE TRUE
ENST00000395040 ENSG00000007264 HEK293_DMSO_6hA HEK293_OSMI2_6hA MATK protein_coding protein_coding 44.80419 32.19915 67.26458 3.588724 14.93389 1.062591 8.209056 8.427066 13.901695 2.3146878 2.6031657 0.7214849 0.16892083 0.25173333 0.21276667 -0.03896667 0.759054738 0.009658657 FALSE TRUE
MSTRG.16185.15 ENSG00000007264 HEK293_DMSO_6hA HEK293_OSMI2_6hA MATK protein_coding   44.80419 32.19915 67.26458 3.588724 14.93389 1.062591 4.132433 3.062510 5.579499 0.1802164 0.7202251 0.8633012 0.10281250 0.09920000 0.08773333 -0.01146667 0.851075999 0.009658657 FALSE TRUE
MSTRG.16185.17 ENSG00000007264 HEK293_DMSO_6hA HEK293_OSMI2_6hA MATK protein_coding   44.80419 32.19915 67.26458 3.588724 14.93389 1.062591 2.940389 1.217283 6.427973 0.1930138 1.9783596 2.3911384 0.05891667 0.03773333 0.09040000 0.05266667 0.009658657 0.009658657 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_OSMI2_6hA HEK293_DMSO_6hA log2fold_HEK293_DMSO_6hA_HEK293_OSMI2_6hA
ENSG00000007264 E001 0.3340335 0.0265465949 0.082062427   19 3777970 3777972 3 - 0.000 0.270 11.378
ENSG00000007264 E002 2.0669934 0.0089700448 0.939488698 0.98577039 19 3777973 3777974 2 - 0.490 0.499 0.044
ENSG00000007264 E003 5.1920884 0.0107838115 0.128825707 0.50844446 19 3777975 3777976 2 - 0.873 0.648 -0.906
ENSG00000007264 E004 8.7071331 0.0102678079 0.155500933 0.54737815 19 3777977 3777983 7 - 1.055 0.873 -0.677
ENSG00000007264 E005 15.9136342 0.0276322203 0.208632912 0.61271336 19 3777984 3777985 2 - 1.280 1.118 -0.572
ENSG00000007264 E006 31.8318976 0.0009594546 0.254189159 0.65988154 19 3777986 3777994 9 - 1.540 1.463 -0.266
ENSG00000007264 E007 442.8907517 0.0001180947 0.268784412 0.67332391 19 3777995 3778422 428 - 2.634 2.649 0.051
ENSG00000007264 E008 308.7770664 0.0001237984 0.337916433 0.73039580 19 3778509 3778592 84 - 2.475 2.491 0.053
ENSG00000007264 E009 209.6815678 0.0002012577 0.482725130 0.82085068 19 3778593 3778595 3 - 2.308 2.323 0.048
ENSG00000007264 E010 416.7616035 0.0001131961 0.028668775 0.27441509 19 3778992 3779132 141 - 2.597 2.632 0.117
ENSG00000007264 E011 290.0264046 0.0001704378 0.072075663 0.40007992 19 3779133 3779187 55 - 2.438 2.474 0.118
ENSG00000007264 E012 208.3607834 0.0002024758 0.179462274 0.57859282 19 3779378 3779388 11 - 2.298 2.329 0.102
ENSG00000007264 E013 306.9309718 0.0001385910 0.149317899 0.53849528 19 3779389 3779451 63 - 2.469 2.495 0.087
ENSG00000007264 E014 190.7724537 0.0014989350 0.499293639 0.82925449 19 3779533 3779541 9 - 2.262 2.286 0.081
ENSG00000007264 E015 346.6404992 0.0019727414 0.239019978 0.64428328 19 3779542 3779617 76 - 2.511 2.554 0.143
ENSG00000007264 E016 385.8342303 0.0002107303 0.033874741 0.29353916 19 3779698 3779788 91 - 2.562 2.600 0.126
ENSG00000007264 E017 190.6755826 0.0007891122 0.306396225 0.70495714 19 3779789 3779797 9 - 2.263 2.291 0.093
ENSG00000007264 E018 307.4514166 0.0001855008 0.114937277 0.48417211 19 3781607 3781672 66 - 2.467 2.497 0.099
ENSG00000007264 E019 29.4120237 0.0981835773 0.089094417 0.43666805 19 3782292 3782426 135 - 1.346 1.616 0.928
ENSG00000007264 E020 85.3270996 0.0144895563 0.976523419 0.99454151 19 3782427 3782671 245 - 1.928 1.922 -0.020
ENSG00000007264 E021 48.8065911 0.0122871231 0.265408793 0.67026267 19 3782787 3782817 31 - 1.725 1.634 -0.308
ENSG00000007264 E022 77.8502356 0.0118627364 0.177300661 0.57593644 19 3782818 3782937 120 - 1.928 1.819 -0.368
ENSG00000007264 E023 376.2346686 0.0001011266 0.294804441 0.69522825 19 3783126 3783219 94 - 2.576 2.553 -0.078
ENSG00000007264 E024 20.5887126 0.0168002894 0.280187328 0.68326210 19 3783220 3783297 78 - 1.280 1.386 0.368
ENSG00000007264 E025 291.2271240 0.0001332104 0.476483983 0.81744252 19 3783814 3783871 58 - 2.463 2.444 -0.063
ENSG00000007264 E026 387.3719638 0.0004563014 0.388845694 0.76626165 19 3783872 3784020 149 - 2.586 2.567 -0.065
ENSG00000007264 E027 178.4874091 0.0002251484 0.377668935 0.75847855 19 3784021 3784033 13 - 2.235 2.255 0.069
ENSG00000007264 E028 361.6774863 0.0001487477 0.376439862 0.75762830 19 3784124 3784239 116 - 2.557 2.536 -0.068
ENSG00000007264 E029 355.7696325 0.0003353464 0.103061744 0.46288816 19 3784338 3784451 114 - 2.557 2.521 -0.121
ENSG00000007264 E030 8.4988709 0.0029295361 0.001692347 0.07300598 19 3784452 3784573 122 - 0.803 1.144 1.272
ENSG00000007264 E031 228.5352465 0.0012772780 0.031145048 0.28396230 19 3784825 3784884 60 - 2.376 2.309 -0.224
ENSG00000007264 E032 101.8800647 0.0067097205 0.012119132 0.19015711 19 3785064 3785096 33 - 2.053 1.906 -0.492
ENSG00000007264 E033 170.6911193 0.0037203142 0.034826163 0.29699217 19 3785097 3785246 150 - 2.259 2.166 -0.311
ENSG00000007264 E034 84.1443591 0.0005053481 0.024254182 0.25539405 19 3785247 3785279 33 - 1.960 1.863 -0.324
ENSG00000007264 E035 56.8704714 0.0029321220 0.848845916 0.96276422 19 3785280 3785286 7 - 1.756 1.760 0.015
ENSG00000007264 E036 3.1274362 0.3505410894 0.720631981 0.92248843 19 3785613 3786024 412 - 0.623 0.556 -0.303
ENSG00000007264 E037 5.4941143 0.0303346930 0.433636879 0.79372028 19 3786025 3786168 144 - 0.834 0.727 -0.429
ENSG00000007264 E038 210.3538329 0.0021730072 0.021810800 0.24440260 19 3786169 3786413 245 - 2.344 2.267 -0.255
ENSG00000007264 E039 0.0000000       19 3787460 3787715 256 -      
ENSG00000007264 E040 0.0000000       19 3789273 3789404 132 -      
ENSG00000007264 E041 0.0000000       19 3793074 3793129 56 -      
ENSG00000007264 E042 0.0000000       19 3793130 3793398 269 -      
ENSG00000007264 E043 0.0000000       19 3793399 3793401 3 -      
ENSG00000007264 E044 0.1125166 0.0326491905 0.849387628   19 3801532 3801686 155 - 0.091 0.000 -8.796
ENSG00000007264 E045 0.0000000       19 3801687 3801812 126 -      
ENSG00000007264 E046 0.0000000       19 3801895 3802129 235 -